Hysingla Experience (Page 2)

This is day 3 of me taking Hysingla 20mg after taking Norco 10/325mg three to four times a day. So far I've noticed some wacky side effects. The pill seems to kick in at around 8hrs, and I can't keep my eyes open, I get a rush of anxiety and nausea. I've taken EVERY other ER opiate in the world and none of them did this to me. I do notice that it has lessened my extreme pain already and I have taken a few norcos on top of it thru out the day, but the 8hr mark seems to be like a different world kicking in. Has anyone been on this for awhile, went thru these side effects and then came out the other end actually liking this med? I can find NOTHING on the internet regarding much experience or reviews out there on people who are taking this med. I've woken up in the middle of the night with abdominal pains, anxiety and an overall feeling of weird. Then it passes and I fall back to sleep, and I just feel so hungover. Also it's like every three hours or so it will ''kick in'' again with the can't keep my eye open thing, the nausea, etc. I started out the first two days not eating much (took away my will to eat) so today I made sure I ate a large meal before the 8 hr mark kicked in, but still feel so freaking weird! Please, can anyone out there give me some feedback?

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Hi donna. I hope your finding relief. When you went back to doctor, what did they do? I'm still experiencing the headaches, cramping and just really tired all the time? Do the side effects get any better? Thank you

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I also have no side affects and it seems to be working. I do still have some pain, but I take it at night and when I wake up I feel so much better. I was taking morphine sulfate 30 mg. 3 times a day but the constipation was just too much for me. I actually like the idea of just taking one pill a day. I did have nausea and headaches in the beginning but that has all gone away. A little constipation and not hungry but try to eat. I think I'll stick with this one. So tired of trying all these different medications.

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Hi Ruth,
Sorry to hear your having such problems :( . I am so happy I stuck it out because now I hardly remember the problems I had in the beginning. My doctor asked me to try and stick with it for at least 4 to 6 weeks and things did get better. It has been about 8 months or so now and I am more stable then ever before. My pain relief has been amazing and I haven't had to increase the Hysingla or my break through Norco. But of course if your side effects do not get better then I'm sure your doctor will advise you as to what you should do. I wish you the very best as I know first hand the disappointment of trying a new pain med only to feel so sick due to side effects _ I have been through so many that didn't work for me. Please feel free to write me anytime.

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Took hysingla for 3 MO.
Quit working after about 8hr. Took 5mg hydrocodone to get by. Now wants me to take lyrica and opana.. Really scares me cause I have bad reaction to morphine.. Also added claritin D.. Any ideas to help?

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I have just started on HYD 20 I have been on NORCO-10 for a long time and they helped the pain but for only 3 hours I have 9 chronic pain diseases...The first time I took this I felt relief and relaxed....I have norco 7.5 for breakthrough I hope this med works

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I read seratonin syndrome can happen. The anxiety u are experiEncino should b told to doc. I take hysingla for many mo.s now. No real s.e. noted. It takes 3 days to get a normal plasma level in the blood stream. Depending on your metabolism.

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Was on hysingla ER 20 mg , Horizont ER 300 mg and tramadol for breakthrough for 6 months. The hysingla ER would get a fair blood level at the 8th hour and would cover my pain fair until the 18th hour. So I was having to go to the tramdol several times a day and running out way to early. Upped my Horizont , but was having cognitive problems and returned to the 300 mg dose. Just went back to immediate release norco instead of hysingla since it failed to cover my pain for the 24 hours.

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It was absolutely the worst med I have ever taken. Side effects were awful.

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My Doctor recently took me off 20 mg twice a day of OxyContin and put me on Zohydro 10 mg twice a day. The Oxy was no longer taking my chronic pain away even with taking 3 Norco 10s a day. Even though the Zo is 12 hrs and twice daily, even with the Norcos still having lots of breakthrough. Have an appointment with her this Tuesday and going to see if she will bump the Zo up to 15 or 20 mg. It is my understanding anyway that OxyContin is stronger than hydrocodone.

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Was on hysingla ER for 6 months.. Would only cover my pain moderately from hour 8 to hour 15 when blood levels were highest and provided almost no relief for the remainder of the 24 hours. Went back to norco IR and notice that ny tolerance is much higher! Before he started me on hysingla I could take a norco 7.5 and I would cover my pain for 4 hours ... Now it takes 1 1/2 to cover with added ibuprofen ...

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I have been on Hysingla 40 mg now for about 2 years and it has changed my life. I had been taking Hydrocodone 10/325 4 x daily for several years and it just wasn't helping as much as my body became so used to it, I had tried several other pain meds but had allergic reactions and so was limited in my choices. I did have some side effects when I first started it and did call my doctor about them_ which I urge everyone to do when in doubt. He told me to try and hang in there for a month and that did it :) after that it worked better and better. Yes I suffer from constipation but that was also a problem on Hydrocodone _ which I still can take one or two for break through pain. Yes my appetite went way down, but I just eat smaller little meals throughout the day and they put me on Linzess to help with the constipation. After trying taking Hysingla at different times of the day I found that when I get up in a.m. I take one Hydrocodone as it works fast and then two hours into that is when I take the Hysingla which then pretty much keeps me pain free for the day, occasionally I do have to take the second Hydrocodone that I am allowed. As to some people saying they can't sleep I never had that problem but that maybe due to the fact I have to take a muscle relaxer each night before bed. Here is the thing if you have been taking Hydrocodone without any problems then the Hysingla is basically the same thing just without the Acetaminophen which of course is bad for your liver. I am so thankful to have found this drug, but everyone is different _ wishing everyone the best.

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I'AM ON 30MG OF HYSINGULAR AND I FEEL LIKE MY LEGS ARE VERY HEAVY DO ANY OF YOU HAVE THAT SIDE EFFECT?

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So sorry Susie. I had a terrible time with that med. Tired, nausea, not eating. My body felt like cement. They did not help. It was absolutely the worst med I have ever taken.

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I have been on hysingla 30mg for about 6months. It has helped me to start taking it at around 10pm, that way when I get up in the morning I feel pretty good so I can go to work. my doctor will not give me any breakthrough pain medicine which would help some. I have to say this medicine has really worked well for me.Hang in there maybe it will do the same for you. Remember take before bed time

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I've been on Norco for years...Hated Lortab, so when i found Norco I felt safer....high heart rate with Lortab...I suffer from a family curse of severe arthritis of the spine for not only a DNA issue but because we were very hard workers without college education....and a few very serious falls...and no food in cabinets or fridge as a kid for a better chance....I went days if not weeks without eating....watched my brother who had 6 discs in his neck fixed...He replaced windshields the old way...He died misusing his meds...OXY plus....Since bam Norco was considered a rating as a class A overnight...I've been put through pain management....my new Dr. since my other Dr. had to go on medical leave...same office..only going over medical reports....bogus!!! The last day to see her i showed her a picture of just my upper back/head....her head bowed as she finally realized I'm in trouble....see my mid back everybody wants to ignore....lower back surgery? Pain is even worse....shots haven't worked yet and if they don't work for my lower back....I can't do it on my neck knowing the pain that comes with it...

My mid back - they tell me nothing is wrong..LIARS...I get stabbings daily!!!! What a joke!!!! Went to physical therapy and was mocked by a EDUCATED(?) 20 year old that would rather talk to her fellow therapist than pay attention to me....I'm 55 and I can't stand disrespect from someone I'm suppose to count on!...DONE with her!!!! She even had the balls to mock me saying you're walking better already....It's not even a joke when you can't stay on your feet for 15 to 20 minutes without severe pain...Thanks for putting everybody in the same box!!!!

My complaint - Why pick on someone who has been on Disability for at least 15 years?... I can't use my arms or legs....Norco was my lifesaver to at least get something done!!! Now I'm stuck in a recliner all dam day....crying every day... Since my new Dr. screamed DEA....Judging me by the cover!!! Now let me tell you what I think of HYSINGLA.... VERY DANGEROUS!!! Turned my finger nails blue...couldn't breath...lost the urge to go #2 without knowing it landed in my pants....had electric shocks from the top of my head...down my legs to my fingertips.... It's DANGEROUS!!!! Get it OFF the market ASAP!

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I have been on hysingla w Norco 10's twice a day for break thru pain. I haven't had any extreme side effects or pain relief either. It is a time release hydrocodone, which is the same ingredient as in Norco. Hysingla has no added tylenol. Lortab was hydrocodone w 500mg of tylenol, Norco is lortab only w less tylenol, 325mg. Hysingla works vert subtly on me. I have to supplement it w ibuprofen. The break through medicine isn't enough either. I exercise, and ice my back. I practice meditation. I know Alabama is suffering from an opioid epidemic as dr. Are prescribing the highest per pt. In the country. I feel I can't ask for an increase in hysingla 30 mg. As in your situation I might get ALL my medicine discontinued. I hope u can find a better long acting med for ur pain.

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My Dr had me on 10,325 excuse my writing IV got a broken hand and wrist now was in severe bad car wreck my back body totally in severe pain did several m r I s Dr put me on 4 of them a day have to have back surgery I can't even hardly walk now pain goes from my neck down my back both hips both legs feet goes numb that's why my bone is sticking up out of my hand fell couldn't walk back to my bed before this my hand he had me taking four a day than he put me on percocet ten three 25 than they was break me out so he put me on hydrodone ten three 25 twice a day than prescribed me this hysingla forty milgram once a day told me if not working Dr would take me off of the forty than put me on sixty if they was not working would put me on eighty if them didn't work wood put me on hundred milg well none of them work just like taking baby aspirin to me didn't get to try the hundred milg out had my records on line every one goes to that clinic has on line well IV had my Dr over five years and someone hacked my account and acted like me try get refill two weeks early on both ofmy pain medicine now I have no Dr at all hurt cry every day plus I have copd can't get none of my medicines

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Hi. My name is Cynthia. I just took my first 30mg dose yesterday. I felt ok at first but last night I started itching and I couldnt.. at about 6 am I felt real bad I started w anxiety and pain in my left arm and chest. And nausea also couldn't keep my eyes open.. I am discontinuing this med..i hope I'm ok after it wears off.. good luck to u

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I've been taking Hysingla for about 8 months now. I have very few problems with it and it seems to help my back pain. I do take Norco 5/325 twice daily for breakthrough pain. The one that I do notice is that it takes maybe 5 or 6 hours before the Hysingla starts to work. I pleased with it, taking it only once in 24 hours is a plus. I have no complaints. I wish you the best with this medication.

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Re: SUSIE (# 34)

Thank you so much for your positive post! I just took my first 30 mg Hysingla today, and I took it right when I got it at 1:30 today. But if that doesn’t work out I will take your advice and try taking it at night. I am only wanting to read positive posts as I’m hoping this new med. helps me.

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