Linzess

Active Ingredient(s): Linaclotide
FDA Approved: * August 30, 2012
Pharm Company: * FOREST LABS INC
Category: Laxative

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Linzess Overview

Linaclotide (marketed under the trade name Linzess in the US and Mexico, and as Constella elsewhere)[2] is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause.[3][4] It has a black box warning about the risk of serious dehydration in children in the US; the most common adverse effects in others are gastrointestinal.[3] It is an oligo-peptide agonist of guanylate cyclase 2C ...

Read more Linzess Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Linaclotide

Recent Linzess Forums: RSS Feed

Excessive Bloating on Linzess

I've been on Linzess for about a week now and the bloating is unbearable. The medication has produced several BM's and I had severe diarrhea the first two days on the medication. The diarrhea has subsided but the bloating continues to get worse. I is painful and it looks like I am 6 months pregnant. My clothes don't fit anymore and I can't find any helpful solutions to the distention. Has anyone had these similar symptoms and do they typically go away? ## Hello, Kristy! How are you? I'm sorry about the problem you're having. Yes, that has been reported by many people and is a known side effect as listed by the FDA. You may also experience weight changes, nausea and dizziness. Can anyone that's taken in chime in on whether or not it's gone away as your bod...

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Passing Parrasites

I've been taking Linzess for a few months now and I must say it gets the job done. Sometimes after taking Linzess I have diarrhea. I've noticed that when I do have diarrhea I pass parasites! Has anyone else experienced this? I have detoxed before with natural herbs and didnt pass a thing. I know Linzess itself kill off parasites but there is def something in it that pushes them out. Has anyone else experienced this? ## I’m taking linzess About three months. And I have had leaky gut whenever I take it two days. Three times I’ve had leaky gut Had pads on and it was covered with parasites , disgusting.! What does this mean? Are they dead or alive???? ## Hello christy, It makes sense to me that it would be a lot easier to pass a dead parasite than to pass a live one sinc...

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On Linzess for a week, NOT "Working" - HELP!

Hi all! I'm new here, but not new to constipation... However, I only got my first *prescription* medication to treat it a week ago when my new PCP finally related enough to my digestive woes and the frustration that comes from years of living through the futile cycle of Miralax, MoM bombs, evil teas, and throwing my hands in the air. She gave me samples of Linzess (low and high dose) and thoroughly educated me on how to take it properly, along with a fair warning to remain near the bathroom those first few days. Honestly, I was pumped! And I know beyond a shadow of a doubt I've taken, and stored, this medicine correctly because I was all in on making this work, as gruesome as those first days might be. But alas, radio silence. I started with the low dose a week ago (a Wednesday)...

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took 2 Linzess capsules by accident

Hello. I forgot I had taken a pill earlier and just took another, will this hurt me? I have been on this medication for a while and just totally forgot I had already taken one. Thanks! ## Were you ok in the end? I'm getting tired of it not working and am considering doubling my 290 dose so I'd like to know what you experienced... ## A single occasion of a double dose could possibly mean an increased risk of it's typical side effects in that moment; but I have my doubts that anything serious or long term would manifest as a result of this one time mishap. However, I too would be interested in hearing how things turned out for you Liz? Hopefully all is good! Have any other patients here had a similar experience on Linzess? For any newcomers on this medication, I see there are ...

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Itching and Rash Treatment

I started taking Linzess in early August and around the end of August I broke out with a rash and had severe itching and had to go to a dermatologist. She thinks I had a allergic reaction so I am taking the linzess twice a week. Its not working as well as before, but I was miserable for a month with the itching. ## Hello, Lulu! How are you? The problem is that even just taking it twice a week may not be safe, if you are allergic to it, because such reactions tend to get worse with time. Have you consulted an allergist or immunologist? That might be a good idea, in order to get a better idea of what's going on. ## Thanks Verwon, I will talk to my doctor about seeing a allergist. I am allergic to aspirin, penicillin, so I need to check into this. again thanks! ## My body itches me and...

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What is meant by being inpacted?

Hi, I know this may sound like a stupid question but I have suffered from Opiate-Induced Constipation for 15 years and have followed several different VA doctors recommendations, none of which really worked or else the VA pharmacy would fill their recommended prescription. My civilian doctor got me approved for Linzess which I have read great things about. By inpacted, I think it means where the stool is backed up and is blocking evacuation but now I am thinking that since opiates cause slow transit of stool through the G.I. tract, that might be the inpaction they are talking about. I have never had a complete evacuation of my G.I. tract (colon), only partial. So which is it? The inpaction around the evacuation point or up through the colon? ## Hello Lartomar, According to Harvard Healt...

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How many days should you take Linzess to 1st bowel movement

I am on Linzess 7 days now had 1 bowel movement after 1sst dose of 290 mg Is it save to continue taking it ## Hello, Sheila! How are you? It would be best to follow your doctor's instructions for whether or not to continue it. Most people do experience bowel movements, shortly after taking it, but it does not work for everyone. Have you made sure to take it on an empty stomach, at least a half hour, before eating or drinking anything else? The FDA lists its typical side effects as possibly including nausea, dizziness, headache, bloating, and diarrhea. ## I have been taking 290 mg linzess for15 days and still nothing should I keep taking it

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Linzess Patient Reviews

I've been taking Linzess (290mg) since May 8th, 2018 and it has really helped me have a complete bowel movement. Now I'm so glad for this medicine, I should've been on it. I can deal with diarrhea ok, don't like it but it beat not being constipated & not being able to completely empty your bowel properly like it should be done. I suffered from not having a complete bowel movement for 6yrs now, due to the fact that my spinal cord was damaged severely in car wreck damages. This causes my bowels to not function properly like it should and stools were not passing through the rectum. My colon was storing up stools in the rectum. Whenever I have a bowel movement I could still feel stools in the rectum and the urge to go was always there. That feeling that I had to go. This...

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linzess weight loss

how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss, so there is no time frame I can give you for this. It is used to treat symptoms of IBS that are associated with constipation. And while that may cause weight loss, in some instances, it can be dangerous to try to lose weight via giving yourself diarrhea, since it creates the risk of malnourishment and dehydration. Common side effects to this drug may include nausea, dizziness and stomach pain. Was it prescribed for weight loss? ## I just received a sample from the dr to help with my weight loss, however, I am shocked at ALL the side affects from people of.horrible weight gain! I am confused, can you please help explain? ## I have IBS. Been taking linzesss for a month....

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Drinking coffee with Linzess

I have been taken my linzess 290 mcg with coffee every day and then I continue to drink my full cup of coffee. My question is can that hurt me? I just read I should take this med with a full glass of water. Have I cause any damage by taking this med with warm coffee? Maybe that's why It has not been working and I am feeling some abdominal pain. thank you for replying back. ## Hello Tawanna, When taking any medication it is best to administer the medication as it is instructed. Linzess is a medication used to treat constipation and irritable bowel syndrome. According to the NIH this medication contains the active ingredient linaclotide (NDC 0456-1202) which lists Diarrhea, Abdominal pain, Flatulence and Abdominal distension as common side effects. It is instructed to have this medica...

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Possible Dosages for this and Related Drugs:

Linaclotide
  • Capsule: 145mcg, 290mcg, 72mcg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Linzess: (5 results)

Sorted by National Drug Code
  • 0456-1201 Linzess 0.145 mg Oral Capsule by Forest Laboratories, Inc.
  • 0456-1202 Linzess 0.29 mg Oral Capsule by Forest Laboratories, Inc.
  • 0456-1203 Linzess 72 ug/1 Oral Capsule, Gelatin Coated by Allergan, Inc
  • 55700-409 Linzess 145 ug/1 Oral Capsule, Gelatin Coated by Lake Erie Medical Dba Quality Care Products LLC
  • 69189-1202 Linzess 145 ug/1 Oral Capsule, Gelatin Coated by Avera Mckennan Hospital

Other drugs which contain Linaclotide or a similar ingredient: (1 result)

Related Linzess Topics:

Linzess weight gain
I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Act... 89 replies
Linzess stopped working
I have been on the 145 dose of Linzess for several years now, and it was like a miracle drug. No side effects, and for t... 31 replies
Linzess Issues
Chronic constipation with 40-50 lbs weight gain... Linzess works with explosive diarrhea within an hour of taking it but... 13 replies
linzess causes weight gain
I am the same. I have lost 85 lbs over the last 1 year. I have gastroparesis. After 120 days on linzess I am up 15 lbs. ... 9 replies
Linzess Allergy
I've been on Linzess for constipation for two weeks. While it has only produced one bowel movement during this time,... 8 replies
linzess prescribed to help with weight loss
Hi! My Dr. Gave me linzess to help with weight loss. HOWEVER, I am reading all the posts about horrible weight gain, I a... 7 replies
linzess/linzess
When I take linzess with food it gives me severe diarrhea Will this be sufficient to clear me out for a colonoscopy ? ##... 7 replies
linzess weight loss
how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss,... 6 replies
Linzess not working
I have been taking linzess off and on for a few months. The first few times it worked great, but now it just makes my be... 6 replies
Linzess, then other meds with breakfast
Just prescribed Linzess for pain med related constipation, to be taken every day in place of my previous regimen. Readin... 6 replies




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