Active Ingredient(s): Linaclotide
FDA Approved: * August 30, 2012
Pharm Company: * FOREST LABS INC
Category: Laxative

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Linzess Overview

Linaclotide, sold under the brand name Linzess in the US and Mexico, and as Constella elsewhere)[2] is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause.[3][4] It has a black box warning about the risk of serious dehydration in children in the US; the most common adverse effects in others are gastrointestinal.[3] It is an oligo-peptide agonist of guanylate cyclase 2C and ...

Read more Linzess Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Linzess Forums: RSS Feed

linzess prescribed to help with weight loss

Hi! My Dr. Gave me linzess to help with weight loss. HOWEVER, I am reading all the posts about horrible weight gain, I am confused!!!!!!! ## Hello, Twinckle! How are you? This medication isn't intended to be used for weight loss, it's actually used to treat chronic constipation. It can cause diarrhea, which could result in weight loss for some, as reported by the FDA, but it can also cause abdominal bloating and distention, which has caused many to think they were gaining weight on it. Can anyone that's been on it chime in with their experiences? ## Hello, Linzess can certainly be prescribed for the purpose of weight loss! People do not understand how medications can treat multiple...repeat MULTIPLE conditions, diseases and illnesses. Botox is FDA approved to also treat head...

linzess weight loss

how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss, so there is no time frame I can give you for this. It is used to treat symptoms of IBS that are associated with constipation. And while that may cause weight loss, in some instances, it can be dangerous to try to lose weight via giving yourself diarrhea, since it creates the risk of malnourishment and dehydration. Common side effects to this drug may include nausea, dizziness and stomach pain. Was it prescribed for weight loss? ## I just received a sample from the dr to help with my weight loss, however, I am shocked at ALL the side affects from people of.horrible weight gain! I am confused, can you please help explain? ## I have IBS. Been taking linzesss for a month....

Linzess or other Drugs blocking weight loss

I eat very clean, rarely at restaurants. I have been on Linzess (Lazy bowels) for years, been on synthroid (subclinical hypothyroidism) for several months now along with simvastatin for high cholesterol (hereditary). All blood work shows perfect numbers. I have done several variations with my macros monitored by a trainer. I have not been able to drop any weight in 3 years. No one understands, not even the doctors. I am a personal trainer my self and work out 5-6 days a week. I’m about to stop all prescribed meds because I don’t know if they may be causing the issue. I feel like I’ve been beating my head against a brick wall! Any suggestions? ## Synthroid has been known to cause increased appetite, but both the Linzess, and the Simvastatin are known to cause weight los...

controlled constipation relief

I'm a stroke survivor who, post stroke, suffers from extremely irregular bowel movements sometimes going 5 days without a BM, I don't have pain or bloating, I do suffer from acne breakouts ocassionally which is kinda embarrassing for a man in his 50's. Testing provided a diagnosis of 'slow motility', i.e. part of my brain injury from the stroke affected the function of my digestive system) I was prescribed Linzess 290 mcgm daily to address this problem and to restore BM regularity. I only take the medication on Mondays and Fridays as i work from home on those days and my home office is next door to the toilet, otherwise I run the risk of a bowel evacuation at the office which would be humiliating. I take the medication on an empty stomach with a 12oz glass of water a...

Linzess not working

I have been taking linzess off and on for a few months. The first few times it worked great, but now it just makes my belly rumble, then I have to push to get anything out and it's still hard. ## Hi I agree.The first week I was on linzess it work to well vut it still helped but now that im back on it its been two days and still nothing.. what did you do or why is it my stomach just rumbling but im not going. ## It should be taken as prescribed by your doctor, which is usually daily. Additionally, it needs to be taken with water, on an empty stomach, at least 30 minutes before eating or drinking anything else. The FDA lists its typical side effects as possibly including nausea, dizziness, abdominal cramping, bloating and diarrhea. Does anyone else have any advice or ideas that may he...

how long after you take linzess to work

The 290 gave me severe diarrhea and cramps but lower soaw no bm I tried waiting a day then take again had horrible round hard stool a few of them passed only with manipulation and bleeding so I took same day the 290 and nothing but can feel it there making it difficult to sit or walk. ## I'm sorry, perhaps I am not understanding you. You said you did not have a BM, but also say it gave you severe diarrhea, and diarrhea is having a BM, even though it is runny and likely not your usual consistency. Can you please clarify? Did you make sure to take it correctly, which is a half hour, before eating, or drinking anything else? Diarrhea can be a normal side effect of Linzess, along with nausea, cramping, and flatulence.

Linzess weight gain

I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Actually, since it usually causes gastrointestinal side effects, including diarrhea, it's usually known to cause the opposite problem of weight loss. You should also be informed that some people develop serve, ongoing diarrhea, so you need to watch out for that and contact your doctor if it happens. Learn more Linzess details here. Is there anything else I can help with? ## I've gained 4 pounds in 3 days since I started taking Linzess. I am on weight watchers so I count points so I know it is not my food intake. I don't usually fluctuate in pounds so I think it's the new meds. I am still taking Miralax but it doesn't seem like either are working. I loo...

New Insuance denied my Linzess RX B/C I don't have cancer!

I have been on Linzess for over a year now, and happy enough with the results. I had been covered through Blue Cross/Blue Shield of NC. There was NO problem getting the rx filled. Now I am covered through BC/BS of Minnesota. I received a letter denying the rx stating that I am not eligible because I don't suffer from active cancer pain! What the heck are they talking about?!?! Has anyone else run into this kind of issue with their insurance?? ## Appeal it and they might. Your doctor may have to do a prior auth, but I would fight it. I have before with other meds and other insurance and it works. ## Thanks for your reply. Unfortunately I have already appealed and I have still been denied. ## That is very odd, since Linzess is used to treat IBS with constipation, and idiopathic chroni...

72 mg Linzess experiences

Anyone taking the 72mg dose of Linzess, and what are your experiences with it? I just filled the prescription and want to try, just worried. Thanks. ## Hello Drew, According to the NIH linzess has the following adverse reactions. For all of these only 10% of users experienced these symptoms. - Diarrhea - Abdominal pain - Flatulence - Abdominal distension - Viral Gastroenteritis - Headache It's smart and understandable to be cautious when taking new medications. If you feel that any of your symptoms are out of the ordinary or too severe for you to handle please consult your doctor as you may be having an allergic reaction. Have a wonderful day and I hope this helps.

Excessive Bloating on Linzess

I've been on Linzess for about a week now and the bloating is unbearable. The medication has produced several BM's and I had severe diarrhea the first two days on the medication. The diarrhea has subsided but the bloating continues to get worse. I is painful and it looks like I am 6 months pregnant. My clothes don't fit anymore and I can't find any helpful solutions to the distention. Has anyone had these similar symptoms and do they typically go away? ## Hello, Kristy! How are you? I'm sorry about the problem you're having. Yes, that has been reported by many people and is a known side effect as listed by the FDA. You may also experience weight changes, nausea and dizziness. Can anyone that's taken in chime in on whether or not it's gone away as your bod...


Possible Dosages for this and Related Drugs:

  • Capsule: 145mcg, 290mcg, 72mcg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Linzess: (5 results)

Sorted by National Drug Code
  • 0456-1201 Linzess 0.145 mg Oral Capsule by Forest Laboratories, Inc.
  • 0456-1202 Linzess 0.29 mg Oral Capsule by Forest Laboratories, Inc.
  • 0456-1203 Linzess 72 ug/1 Oral Capsule, Gelatin Coated by Allergan, Inc
  • 55700-409 Linzess 145 ug/1 Oral Capsule, Gelatin Coated by Lake Erie Medical Dba Quality Care Products LLC
  • 69189-1202 Linzess 145 ug/1 Oral Capsule, Gelatin Coated by Avera Mckennan Hospital

Other drugs which contain Linaclotide or a similar ingredient: (1 result)

Related Linzess Topics:

Linzess weight gain
I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Act... 91 replies
Linzess stopped working
I have been on the 145 dose of Linzess for several years now, and it was like a miracle drug. No side effects, and for t... 31 replies
linzess prescribed to help with weight loss
Hi! My Dr. Gave me linzess to help with weight loss. HOWEVER, I am reading all the posts about horrible weight gain, I a... 22 replies
Linzess Issues
Chronic constipation with 40-50 lbs weight gain... Linzess works with explosive diarrhea within an hour of taking it but... 13 replies
linzess weight loss
how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss,... 9 replies
linzess causes weight gain
I am the same. I have lost 85 lbs over the last 1 year. I have gastroparesis. After 120 days on linzess I am up 15 lbs. ... 9 replies
Linzess Allergy
I've been on Linzess for constipation for two weeks. While it has only produced one bowel movement during this time,... 8 replies
Linzess not working
I have been taking linzess off and on for a few months. The first few times it worked great, but now it just makes my be... 7 replies
When I take linzess with food it gives me severe diarrhea Will this be sufficient to clear me out for a colonoscopy ? ##... 7 replies
Linzess, then other meds with breakfast
Just prescribed Linzess for pain med related constipation, to be taken every day in place of my previous regimen. Readin... 6 replies

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