Epclusa

Active Ingredient(s): Sofosbuvir + Velpatasvir
FDA Approved: * June 28, 2016
Pharm Company: * GILEAD SCIENCES INC
Category: Hepatitis

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Epclusa Overview

Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed dose combination medication for the treatment of hepatitis C.[2] It combines sofosbuvir and velpatasvir.[2] It is more than 90% effective for hepatitis C genotypes one through six.[2] It also works for hepatitis C in those who also have cirrhosis or HIV/AIDS.[2] It is taken by mouth.[2] The combination is generally well tolerated.&a...

Read more Epclusa Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Velpatasvir/sofosbuvir

Recent Epclusa Forums: RSS Feed

Poste epclusa symptoms

3mths after treatment with epclusa,numb fingers ,toes ,no energy at all severe anxiety pain in knees ,I'm 65 yes old, before treatment I felt fine enjoyed life now it's opposite wish I could feel normal again.i told liver nurse she said "you were probley going to get unwell symptoms anyway'i do not believe this and blame epclusa,I'm in Australia during treatment I had know support from liver clinic or liver Dr. ## You are not the first person to report such issues after finishing treatment with Epclusa. There are several posts on this site, and others, all from people dealing with similar issues. Everything you've described is listed by the FDA as normal side effects of the medication that should, theoretically, go away once you have finished your course of treat...

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Nervous system damage from epclusa

Has anyone experienced severe anxiety, constant crawling feeling in body after epclusa treatment. Its like my brain and body aren't working right anymore? I had terrible side effects. Finished in January, now it's June and feels like I'm still taking the poison. ## Hello, Barbara! How are you? Has there been any change? Those are not normal side effects of this medication according to recent FDA reports. They typical include nausea, dizziness, insomnia, depression, and diarrhea. Are you on any other medications? Do you take any supplements? Do you drink a lot of sugary, or caffeinated beverages? ## Yes I started with hand/arm pain about a month after starting treatment. Now I am three months post treatment and the pain has now been nerve pain in my hands, lower legs, hands, ...

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Epclusa aftermath

Beginning January I completed 3 months of Epclusa, n now am every day dealing with foot,ankle and lower leg swelling. What has happened, am adjusting my diet to minimize effects of that n nausea; it was into the third month that these conditions began to settle in! so far there has been no knowledgeable feed back, like the specialist are only guessing; this is very disconcerting to me. ## I don't know if you know about the lawyers in Texas helping people on harvoni, but epclusa has half of the same medicine in it. They told me to get more people to call. Their name is George Fleming 1-713-621-7944. I took it a year and a half ago and I'm still messed up with my nervous system. Please call them!!!! This may be our only chance. Spread the word to more epclusa patients. ## Hi been ...

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Post Epclusa Heat Exhaustion

Finished Epclusa 2 months ago and hot weather is making me very exhausted, plus my legs have mild edema. I'm 65yrs old and dont know if the treatment was successful yet. ## Hello Davoe, This is perfectly normal. Reportedly it takes roughly 12 weeks before the doctors will run tests to see if there is no longer a virus load and even when the tests show that the treatment was successful the body will still need additional time to heal. The healing process length is a case by case basis due to variables such as exercise regiment, diet, age, the bodies ability to recover etc. During the healing process you are already going to be fatigued more than normal and adding heat to the equation will only result in more exhaustion. Just be sure to appropriately hydrate and take as many breaks to...

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epclusa treatment hep c hearing loss

Im sure epclusa caused hearing problems started with ears ringing then lost hearing in right ear dr prescibed predestone (steroid ) lucky for me hearing came back dr said i was very lucky, liver clinic nurse said epclusa would not cause it i think it did iv never had hearing problems ,id been taking epclusa for 7 days ,its a 3 mth treatment iv done 2 mths dont know if i shud risk doing the last mth im over 60 yrs old ,very hard to get liver clinic to respond or suggest anything. Please any ideas.??? ## Hello Lou, I have been looking into epclusa but I haven't been able to find any reliable source that shows any connection between hearing issues and this medicine. While I couldn't find anything regarding a connection between epclusa and hearing I was able to find some studies tha...

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Starting treatment soon for genotype 3 hepatitis C - have had it for 30 years

Can I get any feedback from someone who's been in a similar situation? I have a very physical job... Am i going to be too sick to work? ## There is really no way anyone can say for sure, since we are all different and may not react the same to any given medication. In most cases, people try to start a new medication, when they have a few days off, that way you can find out how it is going to affect you, before working, driving, or operating heavy machinery. The FDA does warn that it could cause nausea, dizziness, stomach pain, and diarrhea as side effects. Have you started taking it, yet? Can anyone with experience taking it chime in? ## I am also genotype 3 and 30+ years. For the most part I've been ok on Epclusa. (This is the final week) but if I don't drink enough water I...

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swollen hands and feet

Hi, I have COPD and my bloodpressure is normal, but I get swollen hands and feet. I went too the dr. And they perscribe hypace 5ml and raidac 12,5 ml. Raidac to be taken once a day and hypace half in morning and half in evening. My question is if I don't have hypertension, why did they perscribe me with these tablets and won't it make my BP drop. The swelling is caused through the COPD and they say I am not getting enough oxzygen too my heart. Please help me too understand why I have too use these meds. Too scared too take them. ## Hello, Edward! How are you? Many medications have multiple uses, so these ones are often prescribed to help with heart function, so your heart works more efficiently. The U.S. FDA lists the typical side effects as possibly including nausea, dizziness,...

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Hvc treatment

Is it worth doing epclusa? I'm supposed to start next week. I'm 65 yrs old, diagnosed with copd recently and have shortness of breath, always tired & afraid that treatment will make me feel worse. I'm fibroscan f1, geno 3 V L 8mg. I'm very worried. I probably got infected in the 70s and don't feel real bad from hvc yet, just normal old age feelings I think. Any advice is greatly appreciated. ## Hi Lou, Sorry to hear about the symptoms you've been experiencing. Although I've never taken Epclusa myself, I did want to share a link to other related discussion threads here on MedsChat where you may be able to get a better idea of how others have responded to treatment at: [1] medschat.com/search/epclusa Please note that all medications carry some level of risk...

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Epclusa Treatment

Is there anyone out there who has taken Epclusa? I'm fixing to start treatment and would like some feedback. ## When you are starting treatment? Can anyone that's been on this medication chime in? The FDA lists the typical side effects as possibly including headache, diarrhea, discouragement, loss of appetite, and nausea. ## I finished 3 months in Jan; side effects began to like stick to me by the beginning of the 3rd month; swelling for me n nausea, felt a little addicted too; that could have been the habit of taking it at 11am daily. Yet something just isnt right for me n there is no info from the professionals! I'm doing research as much as I can and making adjustments... ## I am currently 12 weeks into a 24 week epclusa treatment. It’s been really difficult due to ...

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Side effects of epclusa

I have been taking epclusa for two weeks. Last night my husband noticed brownish splotches on the mid-section of my back. The skin is not raised nor does it have any similarities to a rash. It looks more like large bruises. I'm not sure if this is from the meds or because I had a heating pad on my back the other evening. Has anyone else had this experience? ## Not all rashes are raised and/or itchy. Some of them are just surface spots like that, and this medication has been known to cause them in some people that take it. However, on your medical provider can say for sure. Have you experienced any other side effects? The FDA lists them as possibly including nausea, dizziness, headache, fatigue, diarrhea, and loss of appetite. Are the spots still there? Are you on any other medicatio...

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Possible Dosages for this and Related Drugs:

Sofosbuvir + Velpatasvir
  • Tablet: 400mg + 100mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Epclusa: (1 result)

Sorted by National Drug Code
  • 61958-2201 Epclusa Oral Tablet, Film Coated by Gilead Sciences, Inc.

Drugs with one or more similar ingredients: (7 results)

Related Epclusa Topics:

Epclusa and leg and back pain
Has anyone taken Epclusa and experienced back and leg pain? I already have 2 herniated discs but it seems that since I s... 18 replies
Epclusa aftermath
Beginning January I completed 3 months of Epclusa, n now am every day dealing with foot,ankle and lower leg swelling. Wh... 10 replies
Epclusa Treatment
Is there anyone out there who has taken Epclusa? I'm fixing to start treatment and would like some feedback. ## When... 9 replies
epclusa treatment hep c hearing loss
Im sure epclusa caused hearing problems started with ears ringing then lost hearing in right ear dr prescibed predestone... 5 replies
Post Epclusa Heat Exhaustion
Finished Epclusa 2 months ago and hot weather is making me very exhausted, plus my legs have mild edema. I'm 65yrs o... 2 replies
Poste epclusa symptoms
3mths after treatment with epclusa,numb fingers ,toes ,no energy at all severe anxiety pain in knees ,I'm 65 yes old... 1 reply
Side effects of epclusa
I have been taking epclusa for two weeks. Last night my husband noticed brownish splotches on the mid-section of my back... 1 reply
Nervous system damage from epclusa
Has anyone experienced severe anxiety, constant crawling feeling in body after epclusa treatment. Its like my brain and ... 67 replies






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