Adderall Manufactured By Teva Not Working (Page 50)
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I have had two refills of Adderall 20 mg that was manufactured by Teva/barr (Teva) and it seems to have much less medication in each pill. Refills by another manufacturer work. This is ridiculous, and where do we report Teva and who can check each pill for amount for medication? I would gladly donate some of my worthless ones to the FDA?

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I agree!! The past 3 times Ive got my prescription filled from Walgreen's, the Adderall is definently NOT as effective as it used to be!!

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Re: sideto26 (# 405)

Based on the complaints online, Aurobindo and Mallinkrock are the worst. I'm happy that the Aurobindo manufactured generics work for you though.

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Re: Dave (# 404)

Hi there. I am in the same boat as everyone else. It's so frustrating to go through this every month. I have tried just about every generic and here's the deal....
I have found that Corepharma and Sandoz brands to work well with little to no side effects. Sandoz is hard to find and Corepharma is in fact a done deal... no longer making it. Some places still have inventory left.

During the past three months I have had the following:
July - Teva 20mg IR ( I found this to be very weak and found myself yawning )
August - Corepharma 20mg IR (Again, this manufacturer works well for me and does exactly what it should do...smooth, optimal focus, no side effects)

**September - Aurobindo 20mg IR ( This was the ONLY thing available at most places so I said screw it and gave it shot. Despite what most have said, I was PLEASANTLY surprised with the results. I would actually say it's better than Corepharma in terms of optimal focus, positive mood etc.. )

I would rate them like so:

1. Aurobindo
2. Corepharma
3. Sandoz
4. Teva

I have NOT tried Mallinckrodt Generic but that seems to have the most consistent BAD, TERRIBLE feedback so I hope the notes above help you out.

I will also say that altering the dosage 10mg vs 15mg vs 20mg does make a difference from brand to brand in terms of how effective it is.

Good luck and keep us posted on your findings!

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Anyone had any experience with global, impax or Sandoz? I am simply in a quagmire, as I can't find a good generic IR that works

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What concerns me concerning generic meds:

When a generic firm decides to file an application to the FDA for manufacturing a medication, they are required to conduct "tests" to confirm that the bioavailability is commensurate with the brand name product.

They must also show that their product's bioequivalency is satisfactory with FDA standards.

My concerns:

The "tests" are conducted solely by the generic firm.

The process and results are not made public.

One wonders if there is appropriate external and internal validity.

Also concerning that we the public, are not able to view the data, and more importantly, the specific --process-- in which testing was conducted.

Then after their product is approved, FDA oversight to ensure quality standards is very poor.

You would need to be poignantly naïve to think that the FDA is available to oversee these, mostly, Third World country firms in an appropriate way.

This is simply profoundly concerning to me.

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Re: Edward (# 400)

No. It has nothing to do with brand vs. generic Adderall. It is comparing "Adderall" vs. Vyvanse.

Basically, it says that Adderall (brand or generic..ha) has a 3:1 ratio of Dex to Levo compared to Vyvanse. Bottom line is the Dex is the "feel good" dopamine enhancer and the Levo is the adrenaline side. You'll get the jittery feeling from the Levo but not as much as the feel good Dex.

Vyvanse was Shire's way to ensure the med could not be abused (it goes through your digestive system very slowly) like Adderall (although the latest Adderall seems to be missing most of that Dex!). They also came out with this as Adderall XR lost its patent and it was a great way to maximize loss profits (Vyvanse ain't cheap)!

With this said, I am NOT a Dr. and all meds should be discussed with your Doc. Find the one that works for you and ensure your Doc writes it on the script.

Good luck!

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Re: Nick (# 397)

Absolutely agree with you. The recent Adderall wave- regardless of manufacturer- lost most of the previous "umfuff " factor..like they purposely shorted the amp portion.

We are not Dr.'s and what we post should only be taken as personal experience.

Try them all and see what works and ensure your Doc specifies it on the script!

Good luck!

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Re: Hamster (# 396)

Very useful information. I read this as Brand has a 3:1 mixture of D-Amp to
L-Amp while the generics have a 2:2 mixture, yes?

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Re: James (# 387)

Honestly, I don't know. Shire would be my best guess. I've never taken Brand so...my apologies for not being more helpful.

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Re: Erin (# 393)

Before you give up on Teva entirely, instead of taking your normal 20mg dose each day...try taking 15mg or
25mg instead of the 20mg for a few days. My experience is that with this slightest of adjustments...you can and will get to that place where your generic Adderall "works".

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Re: Hamster (# 396)

I used to switch back and forth between adderall and vyvanse, every two months or so in college. The hyper focusing part can happen, it helped me because I'd spend hours at a time studying in the library.

I don't find adderall has the same energizing/motivating effect as the old formula, plus the differences between generics lacks the consistency month to month that is crucial to me functioning. Vyvanse on the other hand is just vyvanse, no changes as far as I'm concerned.

Whatever helps you the most is the one that's better. I'm not a doctor but I'd recommend trying both for a few weeks to see what works the best

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Re: Nick (# 395)

Hi,
I tried Vyvanse and did not like it as it lacked the motivation aspect of Adderall. In addition, it lasted maybe 5 or 6 hours and I found myself hyper focusing, quick tempered and did not like the fact you could not "regulate" the dosage. With that said, we are all different so use my account only as an opinion as others like the alternative and it is very clean.

Here are the differences, per document I pulled up several months ago:

Any answer to the question 'what's the difference between Adderall and Vyvanse?' must include a discussion about dextroamphetamine and levoamphetamine.

That's because Adderall contains both d-amp (dextroamphetamine) and l-amp(levoamphetamine). Vyvanse is just metabolized to d-amp - it lacks the l-amp component.

The d or l before the amphetamine signifies the handedness of the molecule. It turns out that (chiral) molecules come in pairs - there are left and right mirror images - just like you have left and right hands.


Because they're just mirror images, you'd think that d-amphetamine would have the same biological effects as l-amphetamine. But this is not the case.

What’s the difference between dextroamphetamine and levoamphetamine? Chemically, these two molecules are mirror images (stereoisomers) of each other and have similar but not identical effects in the brain. Some differences include:
•dextroamphetamine is three to fivefold more potent than levoamphetamine
•dextroamphetamine has greater effects on dopamine than noradrenaline, whereas levoamphetamine affects norepinpehrine slightly more strongly than dopamine
•Both isomers effectively treat ADHD
•Levoamphetamine more specifically improves sustained attention than dextroamphetamine1, which may benefit some subtypes of ADHD
•The 3:1 mixture of dextroamphetamine and levoamphetamine in Adderall was found to have a synergistic effect by enhancing and prolonging the efflux of dopamine produced primarily by dextroamphetamine

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Re: Angela (# 392)

Vyvanse, like adderall, is a stimulant used to treat ADHD. It's effects are slower to come up, but last longer as it "works" through the digestive system. It's less jittery than adderall, and overall smoother in my opinion. Do your own research to hear other peoples experiences. It was very effective for me.

Regarding the brands of it, I believe there is only the name brand "Vyvanse"

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Re: James (# 387)

Teva is the least effective generic I've tried by far. Sandoz has gotten weaker in the last year. I was having good experiences with Corepharma until they decided to stop manufacturing Adderall. For my most recent refill I was only able to find Aurobindo in my area. After reading all the horror stories about Aurobindo I was prepared for an entire month of poor productivity and diminished mental clarity. However I was pleasantly surprised! Aurobindo's adderall seems just as effective as Corepharma to me. It can feel a little harsh at times, but after an hour in to the dose all the mild side effects fade and I'm left with all the benefits of this medication.
I guess everyone's body reacts differently to the fillers in these pills. I got lucky this time, and I'll report back if Aurobindo loses efficacy or if side effects become more prevalent.

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Re: Angela (# 390)

Have you a substitute for Corepharma yet? I'm asking my pharmacist to reorder from a different manufacturer as my 20mg from Teva are terrible. Feels like a placebo. Please let me know!

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Re: Nick (# 391)
I've never had vyvsain so could you tell me what's the difference between that and adderall ? Also which vyvsain brand do u reccomend taking ? Thanks for your time and help :)

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Re: Angela (# 390)

I swichted from Aurobindo 20mg IR to Teva 20mg two weeks ago.

Because of all the changes in manufacturers and the inconsistencies in each brand, I would recommend switching to Vyvanse. That's what I'm doing. I don't want to deal with trying to find the best brand every month. Whether it be generic or brand name Teva, they're both not nearly the same as Adderall used to be.

I've taken Vyvanse before via prescription and had excellent results.

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Re: Nick (# 381)

Which one have you switched to ?which would u reccomend I was on corpharma and thought they were the best but now there being discontinued and have to refill in the next few days ..

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Re: James (# 385)

Teva is still producing the Adderall 20mg IR as of 2 weeks ago when I picked up my prescription.

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Re: James (# 387)

Is Teva who makes IR, I tried it a couple of months ago and posted here. Good thing I only got a script for a trial (7 days) because instead of helping me they actually made things 3 times worse.

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