Prolia

Active Ingredient(s): Denosumab
FDA Approved: * June 1, 2010
Pharm Company: * AMGEN
Category: Osteoporosis

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Prolia Overview

Denosumab (trade names Prolia and Xgeva) is a human monoclonal antibody[1] for the treatment of osteoporosis,[1] treatment-induced bone loss, metastases to bone,[1] and giant cell tumor of bone.[2] Denosumab is contraindicated in people with low blood calcium levels. The most common side effects are joint and muscle pain in the arms or legs.[3] Denosumab is a RANKL inhibitor,[1] which works by prev...

Read more Prolia Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Denosumab

Recent Prolia Forums: RSS Feed

Prolia side effects

Would like to know of side effects after Prolia infusion from other persons. Up to now I have none. ## Prolia is used to treat or prevent Osteoporosis, specifically in post-menopausal women, it contains the active ingredient Denosumab. I'm glad to hear you've had no side effects, however, they can include: skin infections, jaw bone problems, irritation at the injection site and hypocalcemia. Read more: Is there anyone else with experience using this? ## How are you doing now? Still now side effects? Please let us know ## I was given a shot of prolia 8 days ago. I am suffering from pains in my arms and legs, digestive discomfort and nausea. Has anyone had this shot as I would like to know how long these side effects last as I am unable to work at the moment. I really feel terribl...

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Prolia & Hair Loss

I've just recently had my second Prolia shot. So far so good...a little back pain. I continually have stress fractures on my feet and have also taken fosamax. My current problem is hair loss & I wondered if anyone else was having that problem? ## Hello, Gracie! How are you? No, this isn't listed from what I can find, but I'll check a couple more sources to be sure and post back. Are you on any other medications? How old are you? ## I'm 57. On no other meds except evista and a pill for reflux. A friend sent me a website that stated that there was a study with some hair loss ## Yes, after my second shot of Prolea, I had two UTIs, fatigue, huge bumps under the skin on my face and all over my scalp, an array of unexplained symptoms like peripheral neuropathy (not diabeti...

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Prolia Loss of Taste and Smell

I have been taking Prolia injections for 2 years now. Over time, I've noticed that my sense of taste and smell has diminished. As of 6 months ago, I have totally lost the ability to taste anything sweet. Desserts of any kind taste bitter to me. I have also been on Levothyroxine (Synthoid) for a few years prior to starting the Prolia, but the loss of taste and smell has been significantly worse since I started the Prolia injections. Has anyone else experienced taste and smell issues taking Prolia? ## Yes I haven't any taste. Feel a little hungry. Then no taste and don't want it. Also my shoulders are really hurting, then goes to my head. I have several health problems but I know my body. Was not a candidate for Prolia at all and I would not take it again. Best of luck to you ...

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prolia success

I have just had the Prolia injection. So far no side affects that I am aware of. Is there anyone who has continued with Prolia (Denosumab) and had positive results after three years? thanks ## There are many people that have experienced good results from Prolia. What you have to remember though, is that most of them have no reason to go hunting up a site like this to find more information on it. The people that usually post on sites like this one are those that have had a problem and are looking for help, or support. Typical side effects of this medication, according to the FDA, may include administration site reactions, muscle/bone pain, cough, swollen joints, and loose teeth. Can anyone that's done well on Prolia chime in with their experience? ## I just completed 2 shots (one ful...

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Prolia Side Effects Duration

Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happen? ## There have been many posts about people suffering side effects, which in theory should wear off in a few weeks, but it hasn't worked that way for many. Here's a link to a post with comments from several people that have been suffering problems: Are you also suffering from problems? ## First injection Feb. One week later could barely walk or use my arms due to pain. Now have back pain, musculoskeletal pain, cholesterol very high and walk with a cane or walker,very seldom drive now, due to arm weakness.AND my doctor said there were no side effects.!!! Will not take second shot in August. ## Have you rec'd any info on your question. Or since May can you...

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Bone loss after Prolia

My hip bone numbers are worse after the 6 month shot. ## Not all medications and treatments work for everyone that tries them, that's why they are usually several choices available in any given therapeutic category. The FDA lists the typical side effects of Prolia as possibly including bladder infection, arm/leg pain and back pain. You may need to speak to your doctor about trying an alternative. Is there anything else I can help with? ## This is a terrible drug. I only took 2 injections in 9/14 and 3/15, but still have the resulting hair damage and jaw pain. My ENT and Dentist both told me that my jaw is messed up...Prolia does mention that as a side effect, but not hair damage. My immune system is weaker too...even 3 years after stopping Prolia. Yeah I'll just take the Osteopo...

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Prolia - Abundance Of Cavities From The Shot

after my last dental hygiene appt. my dentist came in and stated the nurse who cleaned my teeth saw many cavities. they did x-rays. i suddenly have 9 cavities & 2 root canals. i never had this before. i contacted amgen, who produce the shot. they said no one has had trouble w/their teeth, just jaw problems. if anyone has had this type of problem, please write in. thank you ## How long of a time period was there between when you received the Prolia and the dental appointment? Are you on any other medications? The reason I'm asking is because many medications can cause dry mouth, which can allow the bacteria that would normally be washed away by saliva to remain on the teeth and cause higher and faster rates of decay, than normal. Therefore, it may not necessarily be directly rela...

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Prolia side effects ongoing

I had my infusion Mar 4 2015. I have experienced severe stomach pains, leg pains that wake me up at night, a horrible dry cough, near migraine type headaches, very severe weakness, trouble walking, constipation, had to have dental work that I usually have great teeth, some trouble sleeping. My rheumatologist did nothing to try to help me with the symptoms but my primary doctor gave me medication that help with the stomach pains, take Excedrin for Migraines and enteric aspirin for back and body, and other meds to try and find some comfort. I'm somewhat better than the few weeks after the infusion but still have a lot of problems. Hopefully this doesn't last for 6 months. ## Hello, Shirl! How are you? I'm so sorry about what you're going through. Everything you've list...

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Prolia issues and side effects

I am not going to have my next shot of Prolia due 11 June. I have already had two injections and lately have suffered horrible side effects such as terrible constipation, leg and foot cramps, skin rashes, stomach pain,etc. I also found out that Prolia works by stopping the body's own bone production, causing old bone to become denser. This results in probable fractures due to old brittle bones, Prolia also causes low calcium levels in the blood, a weird side effect seeing it is supposed?to strengthen boned! ## I am sorry for your pain and suffering, I am on the "high risk list" for fractures, so having a product that has rebuilt bone mass in MY body is a blessing. No, I don't like the side effects, but I don't want to be in a wheel chair either.. Good Luck To You and...

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teeth problems after taking prolia

I took Prolia two months ago. I am developing loose teeth and sore spots on my gums. Have others experienced similar problems after taking Prolia? I go to the dentist regularly and have had no dental problems for several years. ## Hello, Dorrie! How are you? You should see your dentist to have this checked out. In certain rare cases, Prolia can cause osteonecrosis of the jaw, it's unlikely, but it would be best to have it checked out, to be sure. Other side effects, as listed by the FDA, may possibly include headache, vertigo, sciatica, anemia and rash. Is there anything else I can help with? ## I'm going to my Dentist for an X-ray of jaw bone tomorrow. Just started hurting this weekend which is Memorial Day weekend. So far, I have had every side effect that Prolia offers and my...

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Possible Dosages for this and Related Drugs:

Denosumab
  • Injection: 60mg/ml, 70mg/ml
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Prolia: (1 result)

Sorted by National Drug Code
  • 55513-710 Prolia 60 mg/ml Subcutaneous Injection by Amgen Inc

Other drugs which contain Denosumab or a similar ingredient: (1 result)

Related Prolia Topics:

Prolia side effects
Would like to know of side effects after Prolia infusion from other persons. Up to now I have none. ## Prolia is used to... 2688 replies
Prolia & Hair Loss
I've just recently had my second Prolia shot. So far so good...a little back pain. I continually have stress fractur... 318 replies
Prolia Side Effects Duration
Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happ... 253 replies
Prolia side effects ongoing
I had my infusion Mar 4 2015. I have experienced severe stomach pains, leg pains that wake me up at night, a horrible dr... 181 replies
Prolia issues and side effects
I am not going to have my next shot of Prolia due 11 June. I have already had two injections and lately have suffered ho... 118 replies
Prolia side effects skin rash
I developed a red burning itchy lumpy rash after one injection of Prolia. Mainly on face neck chest arms scalp. Anyone e... 29 replies
Prolia - Abundance Of Cavities From The Shot
after my last dental hygiene appt. my dentist came in and stated the nurse who cleaned my teeth saw many cavities. they ... 21 replies
Prolia Injection Side Effects
Aprox 2 weeks after the prolia injection I started to experience nausea and weight loss. Also, loss of appetite and a ke... 15 replies
Prolia Jaw and gum pain, neck, shoulder arms and hip and thigh pain and tremors
I took my first injection of Prolia mid April, I have gone to my dentist, he suggested a night guard. My rhuematologist ... 10 replies
Prolia, strange side effects?
I am 81 and had my first Prolia Shot May 7, 2015 and after three weeks I have developed a red rash looking sight UNDER t... 9 replies




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