Prolia

Active Ingredient(s): Denosumab
FDA Approved: * June 1, 2010
Pharm Company: * AMGEN
Category: Osteoporosis

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Prolia Overview

Denosumab (trade names Prolia and Xgeva) is a human monoclonal antibody[1] for the treatment of osteoporosis,[1] treatment-induced bone loss, metastases to bone,[1] and giant cell tumor of bone.[2] Denosumab is contraindicated in people with low blood calcium levels. The most common side effects are joint and muscle pain in the arms or legs.[3] Denosumab is a RANKL inhibitor,[1] which works by preventing the development of osteoclasts which are cells that break down bone. It was developed by ...

Read more Prolia Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Denosumab

Recent Prolia Forums: RSS Feed

Prolia side effects

Would like to know of side effects after Prolia infusion from other persons. Up to now I have none. ## Prolia is used to treat or prevent Osteoporosis, specifically in post-menopausal women, it contains the active ingredient Denosumab. I'm glad to hear you've had no side effects, however, they can include: skin infections, jaw bone problems, irritation at the injection site and hypocalcemia. Read more: Is there anyone else with experience using this? ## How are you doing now? Still now side effects? Please let us know ## I was given a shot of prolia 8 days ago. I am suffering from pains in my arms and legs, digestive discomfort and nausea. Has anyone had this shot as I would like to know how long these side effects last as I am unable to work at the moment. I really feel terribl...

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Prolia issues and side effects

I am not going to have my next shot of Prolia due 11 June. I have already had two injections and lately have suffered horrible side effects such as terrible constipation, leg and foot cramps, skin rashes, stomach pain,etc. I also found out that Prolia works by stopping the body's own bone production, causing old bone to become denser. This results in probable fractures due to old brittle bones, Prolia also causes low calcium levels in the blood, a weird side effect seeing it is supposed?to strengthen boned! ## I am sorry for your pain and suffering, I am on the "high risk list" for fractures, so having a product that has rebuilt bone mass in MY body is a blessing. No, I don't like the side effects, but I don't want to be in a wheel chair either.. Good Luck To You and...

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Prolia - Abundance Of Cavities From The Shot

after my last dental hygiene appt. my dentist came in and stated the nurse who cleaned my teeth saw many cavities. they did x-rays. i suddenly have 9 cavities & 2 root canals. i never had this before. i contacted amgen, who produce the shot. they said no one has had trouble w/their teeth, just jaw problems. if anyone has had this type of problem, please write in. thank you ## How long of a time period was there between when you received the Prolia and the dental appointment? Are you on any other medications? The reason I'm asking is because many medications can cause dry mouth, which can allow the bacteria that would normally be washed away by saliva to remain on the teeth and cause higher and faster rates of decay, than normal. Therefore, it may not necessarily be directly rela...

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Prolia & Hair Loss

I've just recently had my second Prolia shot. So far so good...a little back pain. I continually have stress fractures on my feet and have also taken fosamax. My current problem is hair loss & I wondered if anyone else was having that problem? ## Hello, Gracie! How are you? No, this isn't listed from what I can find, but I'll check a couple more sources to be sure and post back. Are you on any other medications? How old are you? ## I'm 57. On no other meds except evista and a pill for reflux. A friend sent me a website that stated that there was a study with some hair loss ## Yes, after my second shot of Prolea, I had two UTIs, fatigue, huge bumps under the skin on my face and all over my scalp, an array of unexplained symptoms like peripheral neuropathy (not diabeti...

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Prolia Side Effects Duration

Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happen? ## There have been many posts about people suffering side effects, which in theory should wear off in a few weeks, but it hasn't worked that way for many. Here's a link to a post with comments from several people that have been suffering problems: Are you also suffering from problems? ## First injection Feb. One week later could barely walk or use my arms due to pain. Now have back pain, musculoskeletal pain, cholesterol very high and walk with a cane or walker,very seldom drive now, due to arm weakness.AND my doctor said there were no side effects.!!! Will not take second shot in August. ## Have you rec'd any info on your question. Or since May can you...

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Once you stop Prolia

I am 55 years old and have lupus, arthritis, and severe osteoporosis. After more than a decade of taking various meds to try to stop my bones from wasting away with no success, I had my first injection of Prolia at the end of December 2015. I am supposed to get my second shot within the week, but have decided against it. Like many of you, I have felt just awful since December: severe bone and joint pain, worsening depression, constipation, exhaustion, and just plain feeling incapable of doing almost anything. When I talked to both my endocrinologist and rheumatologist about my symptoms, my concerns were dismissed and I was told the side effects would only last a few days at the most. My question is have any of you felt better after you stopped taking the Prolia? If so, how long did it t...

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Prolia side effects skin rash

I developed a red burning itchy lumpy rash after one injection of Prolia. Mainly on face neck chest arms scalp. Anyone else? ## Hello, Willy! How are you? That can be a side effect of Prolia, as listed by the FDA. You may also experience nausea, hypocalcemia, asthenia and fatigue. However, since it is itchy, you should have it checked out, because it could be an allergic reaction that requires medical treatment. Is there anything else I can help with? ## Willy, please look under Prolia side effects on this site. We have almost 900 people writing and talking about Prolia. You sort of worded your question wrong to land on the mega load of Prolia problems. Yes, it's from Prolia and requires medical attention. You will probably have to take written confirmation to make any MD believe yo...

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Documenting Daily Prolia Side Effects

I am a 57 year old female who has -2.5 bone density scores on hips and -3.4 in the spine. I used Forteo for 2 years, but because I was scared to death to try any of the biophosphates and Prolia - I lost the benefit from Forteo. It was minimal improvement at best. I had 3 different doctors in 3 different cities tell me that I should use Prolia. I had the injection on Friday, April 11th. I had put the shot off for 6 months after my pharmacy delivered it to the doctor office due to fear and all the forums. So -- if anyone wants to know information, I will keep you posted. Since yesterday, I have had itching in a variety of places and I had a tough time falling asleep last night. I also have some minor cramping in my calves and thighs. So far this is bearable, but I am trusting God to get m...

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Proliau

After the forth shot of Prolia I am experiencing leg pain. I will stop taking the injection but are the side effects able to reverse? ## Hello, Estelle! How are you feeling? I am very sorry about the problem that you've run into. You are not the first to complain about Prolia and I am expecting many more still to follow, it just doesn't seem to work well for many people. And yes, though it will take time, most side effects do eventually wear off. Is there anything else I can help with? ## Ive had 2 shots so far 60 mlgs in 12 months. My dexa scan was very bad all over me . since shots my bonescache 5x worse and head aches cant sleep anxiety. An more. I have other medical problems. Scared not sure if i should stop are go on and do the other 4 shots he ask me to take..... Idk ## Si...

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WHAT MEDICATION NOW -AFTER STOPPING PROLIA?

I HAD TWO INJECTIONS OF PROLIA AND THEN MY DOCTOR SAID WE COULD STOP, BECAUSE I WAS WELL - THAT WAS 2 YEARS AGO. NOW I HAD A TEST AND IT SEEMS MY RESULTS A WORSE AGAIN. MY DOCTOR SAID TO START WITH BONVIVA AGAIN (MEDICATION I USED BEFORE PROLIA) I TAKE CALCIUM 1 CALCIMAGON-D3 FORTE EVERY DAY . ARE THERE OTHER THERAPIES. I HAD NO PROBLEMS WHEN I TOOK PROLIA, BUT I DONT WANT IT ANYMORE BECAUSE OF THE SIDE EFFECTS. ## I found the post on Side effects experienced after a Prolia injection very interesting as I have been having this injection every six months for osteoporosis for the last three and a half years. I have had this injection sometimes in the arm and sometimes in the stomache depending on the nurse/dr. injecting. I must say I have never had any reaction either in terms of a rash o...

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Possible Dosages for this and Related Drugs:

Denosumab
  • Injection: 60mg/ml, 70mg/ml
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Prolia: (1 result)

Sorted by National Drug Code
  • 55513-710 Prolia 60 mg/ml Subcutaneous Injection by Amgen Inc

Other drugs which contain Denosumab or a similar ingredient: (1 result)


Related Prolia Topics:

Prolia side effects
Would like to know of side effects after Prolia infusion from other persons. Up to now I have none. ## Prolia is used to... 2487 replies
Prolia & Hair Loss
I've just recently had my second Prolia shot. So far so good...a little back pain. I continually have stress fractur... 280 replies
Prolia Side Effects Duration
Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happ... 242 replies
Prolia side effects ongoing
I had my infusion Mar 4 2015. I have experienced severe stomach pains, leg pains that wake me up at night, a horrible dr... 180 replies
Prolia issues and side effects
I am not going to have my next shot of Prolia due 11 June. I have already had two injections and lately have suffered ho... 114 replies
Prolia side effects skin rash
I developed a red burning itchy lumpy rash after one injection of Prolia. Mainly on face neck chest arms scalp. Anyone e... 29 replies
Prolia - Abundance Of Cavities From The Shot
after my last dental hygiene appt. my dentist came in and stated the nurse who cleaned my teeth saw many cavities. they ... 19 replies
Prolia Injection Side Effects
Aprox 2 weeks after the prolia injection I started to experience nausea and weight loss. Also, loss of appetite and a ke... 13 replies
Prolia Jaw and gum pain, neck, shoulder arms and hip and thigh pain and tremors
I took my first injection of Prolia mid April, I have gone to my dentist, he suggested a night guard. My rhuematologist ... 10 replies
Prolia, strange side effects?
I am 81 and had my first Prolia Shot May 7, 2015 and after three weeks I have developed a red rash looking sight UNDER t... 9 replies




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