Prolia

Active Ingredient(s): Denosumab
FDA Approved: * June 1, 2010
Pharm Company: * AMGEN
Category: Osteoporosis

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Prolia Overview

Denosumab (trade names Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.[1][2] Denosumab is contraindicated in people with low blood calcium levels. The most common side effects are joint and muscle pain in the arms or legs.[3] Denosumab is a RANKL inhibitor,[1] which works by preventing the development of osteoclasts,...

Read more Prolia Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Denosumab

Recent Prolia Forums: RSS Feed

Prolia & Hair Loss

I've just recently had my second Prolia shot. So far so good...a little back pain. I continually have stress fractures on my feet and have also taken fosamax. My current problem is hair loss & I wondered if anyone else was having that problem? ## Hello, Gracie! How are you? No, this isn't listed from what I can find, but I'll check a couple more sources to be sure and post back. Are you on any other medications? How old are you? ## I'm 57. On no other meds except evista and a pill for reflux. A friend sent me a website that stated that there was a study with some hair loss ## Yes, after my second shot of Prolea, I had two UTIs, fatigue, huge bumps under the skin on my face and all over my scalp, an array of unexplained symptoms like peripheral neuropathy (not diabeti...

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Prolia Loss of Taste and Smell

I have been taking Prolia injections for 2 years now. Over time, I've noticed that my sense of taste and smell has diminished. As of 6 months ago, I have totally lost the ability to taste anything sweet. Desserts of any kind taste bitter to me. I have also been on Levothyroxine (Synthoid) for a few years prior to starting the Prolia, but the loss of taste and smell has been significantly worse since I started the Prolia injections. Has anyone else experienced taste and smell issues taking Prolia? ## Yes I haven't any taste. Feel a little hungry. Then no taste and don't want it. Also my shoulders are really hurting, then goes to my head. I have several health problems but I know my body. Was not a candidate for Prolia at all and I would not take it again. Best of luck to you ...

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Prolia side effects

Would like to know of side effects after Prolia infusion from other persons. Up to now I have none. ## Prolia is used to treat or prevent Osteoporosis, specifically in post-menopausal women, it contains the active ingredient Denosumab. I'm glad to hear you've had no side effects, however, they can include: skin infections, jaw bone problems, irritation at the injection site and hypocalcemia. Read more: Is there anyone else with experience using this? ## How are you doing now? Still now side effects? Please let us know ## I was given a shot of prolia 8 days ago. I am suffering from pains in my arms and legs, digestive discomfort and nausea. Has anyone had this shot as I would like to know how long these side effects last as I am unable to work at the moment. I really feel terribl...

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Prolia side effects skin rash

I developed a red burning itchy lumpy rash after one injection of Prolia. Mainly on face neck chest arms scalp. Anyone else? ## Hello, Willy! How are you? That can be a side effect of Prolia, as listed by the FDA. You may also experience nausea, hypocalcemia, asthenia and fatigue. However, since it is itchy, you should have it checked out, because it could be an allergic reaction that requires medical treatment. Is there anything else I can help with? ## Willy, please look under Prolia side effects on this site. We have almost 900 people writing and talking about Prolia. You sort of worded your question wrong to land on the mega load of Prolia problems. Yes, it's from Prolia and requires medical attention. You will probably have to take written confirmation to make any MD believe yo...

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Prolia Injection Side Effects

Aprox 2 weeks after the prolia injection I started to experience nausea and weight loss. Also, loss of appetite and a keen sense of smell developed. It was difficult to eat or smell cooked food. It has been months and these symptoms have decreased dramatically. In contacting their website they would not confirm or deny this as a side effect of the drug. Has anyone else experienced nausea w/this drug? ## Hi Bonnie, From what I could gather, the following side effects are associated with Prolia, that may be similar to what you had experienced: -nausea -tingling in your fingers, toes, or around your mouth -pain, numbness, swelling, or drainage from mouth, teeth, or jaw -vomiting Referenced from: nlm.nih.gov/medlineplus/druginfo/meds/a610023.html You or your doctor can also report various s...

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Prolia side effects ongoing

I had my infusion Mar 4 2015. I have experienced severe stomach pains, leg pains that wake me up at night, a horrible dry cough, near migraine type headaches, very severe weakness, trouble walking, constipation, had to have dental work that I usually have great teeth, some trouble sleeping. My rheumatologist did nothing to try to help me with the symptoms but my primary doctor gave me medication that help with the stomach pains, take Excedrin for Migraines and enteric aspirin for back and body, and other meds to try and find some comfort. I'm somewhat better than the few weeks after the infusion but still have a lot of problems. Hopefully this doesn't last for 6 months. ## Hello, Shirl! How are you? I'm so sorry about what you're going through. Everything you've list...

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Dental and jaw pain

I've been on Prolea for 1 month after multiple fractures of vertebrae . I've had a lot of dental problems since having my first shot... Increased cavities, one root canal and another one coming up tomorrow and a possible 3rd... My jaw pain gets almost unbearable, never had any of this before... I wish there would be a way to reverse that shot! there has to be something else to help my bones get stronger... ## Prolea, and most other osteoporosis treatments are known to possibly cause dental issues as side effects, along with joint aches, it could also make it slower for you to heal, after having dental work done, so please make sure your dentist is aware that you have been given Prolia. Yes, there are other options, but as I've already stated, they all carry the risk of causi...

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Prolia inj. - duration of treatment?

How many years are you able to take the prolia inj's.? I took it twice a year for 3 years. Once I received my 6th inj. I was told I was finished and to refer to my Dr. ## I was told that you should go off Prolia (take a holiday), then start taking it again. I cannot find any information that this is the case. Can Prolia be taken forever? ## They no longer recommend the holiday that's been mentioned, the official site from the manufacturer advises against it. As to how long one can continue Prolia, it is up to 10 years, depending on the patient's condition, medical history, insurance coverage, and etc. The typical side effects may include adminstation site reaction, hypocalcemia, increased risk of broken bones, and dermatitis. Did they give a reason why you were done after 3 ...

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Prolia Side Effects Duration

Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happen? ## There have been many posts about people suffering side effects, which in theory should wear off in a few weeks, but it hasn't worked that way for many. Here's a link to a post with comments from several people that have been suffering problems: Are you also suffering from problems? ## First injection Feb. One week later could barely walk or use my arms due to pain. Now have back pain, musculoskeletal pain, cholesterol very high and walk with a cane or walker,very seldom drive now, due to arm weakness.AND my doctor said there were no side effects.!!! Will not take second shot in August. ## Have you rec'd any info on your question. Or since May can you...

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Side Effects Following Prolia Injection

I am 60 yrs old and suffer from osteoarthritis, osteoporosis, and myofascial pain syndrome. After discussing with my endocrinologist, I received my first injection of Prolia two days ago. Had diarrhea approximately 12 hrs later in the middle of the night. Awoke the next day with headache over entire head and face. That evening (12:30 am) I vomited approximately 10 times in succession. Awoke 5 hrs later with terrible pain and tightness from the top of my head down my neck, shoulders, and upper back. I am frightened to see where the pain will travel next, especially after reading the posts on this forum. Is there a drug out there to counteract the Prolia. I will definitely not be getting another shot in 6 mos. My doctor told me that the main side effect of this drug is worsening of skin c...

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Possible Dosages for this and Related Drugs:

Denosumab
  • Injection: 60mg/ml, 70mg/ml
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Prolia: (1 result)

Sorted by National Drug Code
  • 55513-710 Prolia 60 mg/ml Subcutaneous Injection by Amgen Inc

Other drugs which contain Denosumab or a similar ingredient: (1 result)

Related Prolia Topics:

Prolia side effects
Would like to know of side effects after Prolia infusion from other persons. Up to now I have none. ## Prolia is used to... 3085 replies
Prolia & Hair Loss
I've just recently had my second Prolia shot. So far so good...a little back pain. I continually have stress fractur... 449 replies
Prolia Side Effects Duration
Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happ... 316 replies
Prolia side effects ongoing
I had my infusion Mar 4 2015. I have experienced severe stomach pains, leg pains that wake me up at night, a horrible dr... 196 replies
Prolia issues and side effects
I am not going to have my next shot of Prolia due 11 June. I have already had two injections and lately have suffered ho... 125 replies
Prolia side effects skin rash
I developed a red burning itchy lumpy rash after one injection of Prolia. Mainly on face neck chest arms scalp. Anyone e... 33 replies
Prolia Injection Side Effects
Aprox 2 weeks after the prolia injection I started to experience nausea and weight loss. Also, loss of appetite and a ke... 27 replies
Prolia - Abundance Of Cavities From The Shot
after my last dental hygiene appt. my dentist came in and stated the nurse who cleaned my teeth saw many cavities. they ... 21 replies
Prolia, strange side effects?
I am 81 and had my first Prolia Shot May 7, 2015 and after three weeks I have developed a red rash looking sight UNDER t... 11 replies
Prolia Loss of Taste and Smell
I have been taking Prolia injections for 2 years now. Over time, I've noticed that my sense of taste and smell has d... 10 replies




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