Prolia

Active Ingredient(s): Denosumab
FDA Approved: * June 1, 2010
Pharm Company: * AMGEN
Category: Osteoporosis

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Prolia Overview

Denosumab (trade names Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.[1][2] Denosumab is contraindicated in people with low blood calcium levels. The most common side effects are joint and muscle pain in the arms or legs.[3] Denosumab is a inhibitor of RANKL (receptor activator of nuclear factor kappa-Β ligand),[1&...

Read more Prolia Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Denosumab

Recent Prolia Forums: RSS Feed

Prolia side effects ongoing

I had my infusion Mar 4 2015. I have experienced severe stomach pains, leg pains that wake me up at night, a horrible dry cough, near migraine type headaches, very severe weakness, trouble walking, constipation, had to have dental work that I usually have great teeth, some trouble sleeping. My rheumatologist did nothing to try to help me with the symptoms but my primary doctor gave me medication that help with the stomach pains, take Excedrin for Migraines and enteric aspirin for back and body, and other meds to try and find some comfort. I'm somewhat better than the few weeks after the infusion but still have a lot of problems. Hopefully this doesn't last for 6 months. ## Hello, Shirl! How are you? I'm so sorry about what you're going through. Everything you've list...

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Prolia Loss of Taste and Smell

I have been taking Prolia injections for 2 years now. Over time, I've noticed that my sense of taste and smell has diminished. As of 6 months ago, I have totally lost the ability to taste anything sweet. Desserts of any kind taste bitter to me. I have also been on Levothyroxine (Synthoid) for a few years prior to starting the Prolia, but the loss of taste and smell has been significantly worse since I started the Prolia injections. Has anyone else experienced taste and smell issues taking Prolia? ## Yes I haven't any taste. Feel a little hungry. Then no taste and don't want it. Also my shoulders are really hurting, then goes to my head. I have several health problems but I know my body. Was not a candidate for Prolia at all and I would not take it again. Best of luck to you ...

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Prolia Side Effects Duration

Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happen? ## There have been many posts about people suffering side effects, which in theory should wear off in a few weeks, but it hasn't worked that way for many. Here's a link to a post with comments from several people that have been suffering problems: Are you also suffering from problems? ## First injection Feb. One week later could barely walk or use my arms due to pain. Now have back pain, musculoskeletal pain, cholesterol very high and walk with a cane or walker,very seldom drive now, due to arm weakness.AND my doctor said there were no side effects.!!! Will not take second shot in August. ## Have you rec'd any info on your question. Or since May can you...

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Prolia side effects

Would like to know of side effects after Prolia infusion from other persons. Up to now I have none. ## Prolia is used to treat or prevent Osteoporosis, specifically in post-menopausal women, it contains the active ingredient Denosumab. I'm glad to hear you've had no side effects, however, they can include: skin infections, jaw bone problems, irritation at the injection site and hypocalcemia. Read more: Is there anyone else with experience using this? ## How are you doing now? Still now side effects? Please let us know ## I was given a shot of prolia 8 days ago. I am suffering from pains in my arms and legs, digestive discomfort and nausea. Has anyone had this shot as I would like to know how long these side effects last as I am unable to work at the moment. I really feel terribl...

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Getting ready to take a Prolia shot

My Oncologist wants me to start Prolia injections in june but my regular doctor is concerned because I take Benacar for high blood pressure and says that Benacar can cause kidney problems and is worried about me taking Prolia as it can cause kidney problems and since i have had kidney failure in the past it could cause me more problems. Should I take Prolia or not? Just wondering. I also need some teeth pulled before I get the shot. I had breast cancer 5 years ago and did Chemo Radiation and had surgery to remove the breast. I am 61 years old. Please give me some insight. ## If possible, it would be good to get these two doctors to discuss it, together, so they can mutually decide what would be best for you. Prolia can be problematic, because it does tend to cause troubling side effects...

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Effectiveness of AlgeaCal instead of Prolia

Need everyone’s advice, good or bad, on AlgaeCal or similar products. Latest DEXA for me is -3.6 which is the worst I’ve gotten. Will not do another Prolia shot due to side effects that have just begun to recede after 2 years. If I had to do one supplement and a couple of exercises, what would you suggest they be? Thanks to all ~ ## Has your doctor made any suggestions? You can learn more about Osteoporosis and treatment options here on Medline Plus. In my mother-in-laws case, when she couldn't tolerate medications, her doctor told to her to eat at least one serving of yogurt a day, because the calcium in it is readily absorbed. There are also some foods listed here according to their calcium content. ## VerFree ~ Thank you for your valuable input. Being dairy intolerant...

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Prolia & ldn

I take ldn for ms...it does help my energy level. My dr wants me to start Prolia for osteoporosis. This drug effects the immune system. I know ldn helps to boost the immune system. Can these 2 drugs be taken together? I need to make a decision soon. I'd like to hear about anyone with ms using Prolia.....I'm scared. ## I just had a Prolia injection 2 weeks ago. I can tell you this, I would rather be in a wheelchair in a nursing home than have this in my system. It completely and totally DELETES YOUR IMMUNE SYSTEM. I'm really sick and need to go to the ER but I cannot be around other sick people without an immune system. I will NEVER have another one in my lifetime. Also have a couple of very needed surgeries scheduled that will most probably be cancelled because I have NO IMM...

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Severe constipation from Prolia injections?

Anyone have this problem? I was given two shots over the last year no problem. Third shot in November and I cannot resolve my severe constipation. Nothing helps. I eat enough fiber, drink enough water, and work out most days. Miralax doesn't help. Any suggestions? ## Heat some prune juice and drink it but make sure you have easy access to a bathroom. Also pitted prunes. Heat them also after adding water to cover and microwaving them till plump. Not all at once. It may work like dynamite!!! Just a cup of the juice at night, go in morning or whenever it wants you to! ## The antibody Denosumab® or Prolia® for skeletal/bone loss issues comes with a long list of side effects with some being very severe. Constipation is among the top three, so it happens quite often. These issue...

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Delaying Prolia injection

I had a tooth extraction. Can I delay my Prolia injection by one month? ## It would be best to discuss it with your doctor, and follow their instructions. The concern is that medications like Prolia have been known to cause osteonecrosis of the jaw, so proper dental care, and maintaining good dental hygiene while taking it are very important. Was your dentist aware that you are on it? The FDA lists other typical side effects as possibly including nausea, back ache, muscle aches, rapid weight gain, and swollen glands in the neck. Are you on any other medications? ## Do not take Prolia if you do not want to loose all of your teeth. I now have none of my natural teeth and in the middle of implants which is extremely expensive. Dentures are not working because of bone disfigurement. I alway...

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Prolia & Hair Loss

I've just recently had my second Prolia shot. So far so good...a little back pain. I continually have stress fractures on my feet and have also taken fosamax. My current problem is hair loss & I wondered if anyone else was having that problem? ## Hello, Gracie! How are you? No, this isn't listed from what I can find, but I'll check a couple more sources to be sure and post back. Are you on any other medications? How old are you? ## I'm 57. On no other meds except evista and a pill for reflux. A friend sent me a website that stated that there was a study with some hair loss ## Yes, after my second shot of Prolea, I had two UTIs, fatigue, huge bumps under the skin on my face and all over my scalp, an array of unexplained symptoms like peripheral neuropathy (not diabeti...

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Possible Dosages for this and Related Drugs:

Denosumab
  • Injection: 60mg/ml, 70mg/ml
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Prolia: (1 result)

Sorted by National Drug Code
  • 55513-710 Prolia 60 mg/ml Subcutaneous Injection by Amgen Inc

Other drugs which contain Denosumab or a similar ingredient: (1 result)