Buprenorphine 8mg 460
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I have been prescribed the 54 411 buprenorphine pills for about 7 years now. After my last doc visit I filled my script and they told me the same thing about the 54 411 not being available anymore and I got the 460's from them instead. My opinion...they SUCK! Feels like it has about 1/4 the amount of the 8mg it's supposed to have in it. I've been struggling all month with trying not to take more than I'm supposed to. I'm prescribed 1 8mg pill a day and have been happily taking that dose for about 3 years now down from 2 a day. Why this change has happened I have no idea but for me it's not a good thing at all. Besides the huge difference in price I have nothing good to say about the 460's. Does anyone know of a pharmacy that still carries the 54 411? I use CVS

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Okay. I’ve been on 4mg a day (half a tablet) for 3 years and I’ve akwahs had RPs not sure what brand they is but they have always been what worked best for me. I’ve been on these 460s for two weeks and I’ve thought about taking my life twice now, I’ve cut myself, I have had panic attacks daily and severe depression. I’m not a person that struggles with either and I’m usually super happy. On top of that I feel dope sick as hell. At this point I’m just about to quit cold turkey because I can’t imagine it being any worse than this and I was never in drugs. I started out on bupe for pain (degenerative disc disease) so I don’t have to worry about cravings. But they are really bad. I’m almost tempted to have it tested in a lab to see if there is anything even in it because we all could just be going through withdrawals or there might be just small enough traces of bupe in there so no one questions urine samples. But they aren’t FDA regulated so who even knows what the heck is in this mess. All I know is I’ve never wanted to die so badly in my life and I’ve never been a depressed person. I’m always happy. What the hell is going on with these meds?

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Re: riggsk0915 (# 8)

If there is any other suggestions that you can help with I would greatly appreciate and I am extremely desperate for any kind of recommendations or advice that I can receive I had only received this manufacturer one time last month from Walgreens pharmacy and I am worried that they are going to give it to me again this month. Now that I am seeing everyone's posts that are similar to mine with the same side effects and burning sensation underneath the tongue which is unbearable and making me feel nauseous and not feel right. I'm hoping that there is something that can be done I don't know what to tell the pharmacy? I need suggestions or recommendations?

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Re: SteveC (# 5)

Last month was the first month that I received this brand as well too and it was from Walgreens pharmacy as well I'd never seen this kind of bottle before I knew something was a little bit off and that horrible burning sensation I could not take it it was just unbearable. I don't know if I should contact Walgreens as well too about this matter because they are now distributing these tablets as well.

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Re: Stephanelle (# 11)

Kroger has the 460 as well they had RP ones definitely leaves burning under tounge totally different from what I was getting

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Yea the pharmacy inside my doctors office !!!! Best thing ever. Never had a prescription not filled there. Besides adderall. They don’t mess w speed. Mostly benzos and opiates, or opiate replacements. I still get the Roxanne’s every single month. If I go to Walgreens they bitch the whole time and give me orange subs with a moon on it, that I actually think are better than the Roxanne’s. Super hard to get though. Chiraq 4 life.

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Re: Bobby (# 39)

I tried the pill which I believe did not contain Naloxone - got sick each time though I attributed the reaction to the fact that it took a long time to disintegrate.The time it takes for Suboxone and the pills to disintegrate caused much of the drug to be swallowed. The drug apparently does not provide relief if swallowed. Hence, my interest in trying Belbuca. The different formula and promise of very fast entry to the system seemed worth trying. But I was never allowed to try it. I moved on. I now take Tapentadol ER (Nucynta) and SR for breakthrough pain. It is by no means perfect, but it does help on most days.

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Re: Michelle (# 38)

Did you try Suboxone or Subutex? There is a difference. Suboxone has buprenorphine plus naloxone and subutex is just buprenorphine. I had a bad reaction to the nnaloxone in Suboxone and it made me very sick and depressed so eventually I was switched to Subutex. After about a 5 days on Subutex I started to feel better and eventually felt normal again. I went through alot of crap before a doctor would switch me to subutex.

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Purdue makes a Buprenorphine product called Belbuca. It is a gel that is placed on the inside of your cheek. The benefit is that it is supposed to disintegrate (and thereby enter the bloodstream) within seconds. I have not tried it, but I wanted to. The most prescribed form of Buprenorphine is called Suboxone, a drug that is purported to help addicts go off of hard drugs. I tried it for pain, and since I don't do drugs, the additives were not a concern. But I could not keep anything down. Over six months I lost 50 pounds. My last hope was the Belbuca, but no one would prescribe it. In the meantime, I have concluded that I have some kind of allergy to the drug. I do believe it to be a useful pain med.

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The sun brand is one of the worst imo. The mylan and sun are my two least favorite brands. Ive been on buprenorphine since 2006 and Subutex since 2010 so I've tried all the Subutex brands over the years. Brand was the best, Teva's was the best generic but they are both gone. Now Rhodes is the best available and the old Roxanne now called hikima is second. The rest are pretty awful and I refuse to use any brand except for those two.

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Ok guys i have no idea why ppl are complaining bout the 460s. I literally dosed at 11 am w this for first timevafter yrs of 54 411s. Its 610pm rn n i hahvnt had to take another 2mg dose. Im absolutly SHOCKED ida had to do atleast 2 more doses of the 54 411s by this time. So until i find less desirable rezults from this brand this is my new fav. I cant believe i feel fine n good rn after just my morning 2mg dose. I have no reason to lie guys. Im a long time suffering addict whos life was saved by bupe. I now have a great paying job n bank account.. But boy i was scared all the negative feedback didnt psych me out n think they're bad. But woooww i feel great like 7 or 8 hrs w no dose. Normally i need atleast 2 more of 54s by now. My honest experience. First time i actually felt euphoria or subs in yrs

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Re: sativabupeyea (# 20)

I agree. Just picked up 12 Sun Pharm 460s from my 60 tab script. at a mom n pop shop. N this is the first time i felt euphoria n opioid warmth since starting. (Mostly suboxone. N the 54 411 roxies or westward or w.e the f*** they are now) i almost feel like i took a blue. No joke. I feel amazing right now after 2mg ROA IN.. Instantly felt my stomach get better n a warm opioid euphoric blanket is over me. Feels like when i first started subs. I don't take them for a buzz. My 54 411 no one even could tell i was on a med. It just made me normal. These seem the same if not a bit better than 54 411s, hmm ill keep u updated. I cant believe 2mg has me feeling amazing. I get we all want what we know, but these 460s are doing me fine so far.

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Re: Manders (# 19)

i agree i got 12 today. Jus did 2mg n it feels jus as good if not BETTER no lie guys. I been on suboxone n tex for over 4 yrs. N these seem the same really. I jus hated the arrow 8s by hi tech. I actually feel an opioid warmth off these 460s n i feel great! No burn in nose or mouth. Is it possible ones getting these effects are either mentally tricking themselves. Or jus being how us addicts are. Me too lol. We want what we want when we want. Try to remember ritual is a huuuge part in addiction n e thing that changes up after using a trusted med for years, will make u anxious n freaky. Act like their good n thry will be. Im feeling fine rite now off 2mg

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Re: KristenGfromGa (# 29)

Do you really like the orange half moon??. Or is it because it's all you can find?? IM just curious about it because most pplni know run from actavis brand that Walgreens carries. I have 5 stores in my area that I can get actavis anytime I want to because that's all Walgreens has carried for many years now..I will always go to the next pharmacy and avoid the orange half moon. I have never found anyone that says they like then..I will always get the hikma 54 411s or new Rhodes Rb b8 they are white round and we finally have a generic worth bragging about I have done subs for almost 15vyears now and nothing ever compared to original brand subutex other than teva b799

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Re: KristenGfromGa (# 29)

I do not and will not ever except the orange half moon from actavis. I dont like anything about them not to mention they have less bup. In them and this is a very expensive medication. The only other one is sun . Now they Mylan is the one that has less bup it . All the others have 8.64 mg of buprenorphine equivalent to 8mgs. The only 2 generics I will accept is hikma 54 411s or the newest generic is Rhodes it's like 2x stronger than the rest , it's very smooth tasting and a very well made pill. They are made by Purdue who put out oxycontin. Purdue makes very good medications .they are manufactured by Rhodes that puts them out. Everyone should get a chance to try them . Everyone I have told this to is very very happy. Someone asked yesterday a question..... which one should I choose at the pharmacy they have both, everyone said Rhodes of course but one person said it correctly there is no comparison it's out of the ballpark get Rhodes.. he did and came back thanking us all for feedback try them follow the money Rhodes new generic buprenorphine came out in Oct 2017 and are showing up slowly us who have them had to hunt and we found them

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Same thing happened with me but I was switched to Hi-Tec brand which are smaller and dissolve faster.

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Re: Charlene (# 27)

Exactly...i.posted a link to complain to FDA awhile back...it said online when two or more people were having same bad reaction to a med that an investigation would begin....so I encourage all who've gotten sick from 460s to speak out!!! We only have power if we scream together!

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Try walgreens...I got the orange 8s from them recently in Georgia....cvs is swapping to 460s from Sun Pharmaceuticals. .look it up...they SUCK!!!!!! I also used walmart and got 54 411s....there's a small pharmacy here called Medicine Cabinet that has small 8s with arrows....hope this helps....

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Re: jj (# 16)

I don't know what inactive ingredients they changed in what was old roxanne... then westward...now owned hikma 54s..but you can go to Google & type in BTODREMS - all the generics buprenorphine will be listed. Any info one might need is there for us that use subutex or suboxone or zubsolv. You will also notice if you look and compare the amount of bup in each generic most will say 8.62 I think equivalent to 8mgs. Mylan has less 8.624mg bup equivalent to 8mg...only two have just plain 8mg bup, that is sun and actavis. So you can check it out. It's a useful tool for us to use along with doctors and pharmacists who use it all the time so look at the ingredients and compare to see what each one has.

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Re: KristenGfromGa (# 26)

I agree with you... you mentioned the 460 make most feel like they are sick and somewhat of a withdrawal feeling..if somehow you or someone could get together even from the other medschat forums on buprenorphine, look through them and find the ones that are only able to get the 460s..together get signatures and go to the head honcho to fight this battle. Because the chain Pharmacies cant, or let's say won't do..they are only workers and want their paychecks at the end of the week..all your chain Pharmacies at least in my area one has one brand. The next another..so I found out a long time ago to use a mom n pop pharmacy. They need your business way more than a big chain Pharmacies. I've never bumped into the few brands like sun, mylan. I've been on subutex since 2007 so its really surprising to me I never even bumped into either one... now in such you bvb all have heard about the new generic Rhodes, they are comparing it to original brand subutex and then teva comes out next. Between teva and Rhodes I was just told they only have one inactive ingredient difference between the two. So that makes Rhodes now even better than the hikma buprenorphine 54's....and I never thought one would ever come out so closely to teva..because everything else that followed has been junk..everyone has a comment about one of them because of the inactive ingredients in each one....not to mention that out of all the generics only 3 have a lower dose of buprenorphine in them. Most will say 8.64mgs of buprenorphine equivalent to 8mgs. So see that's another biggie when choosing your brand of subs. Look at the chart on Google first then choose one and try to get it..some are still listed just not available anymore.

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Absolutely, the same thing is happening to me now. Been on 54 411s or 8->s (arrows lol) for 4 years and had to swap my pdp for Medicare and now have to use "preferred pharmacies" and these preferred pharmacies are only buying the sun pharmaceutical 460s bc they are much cheaper than other makes..I was told this by the pharmacist at cvs in St marys, ga. They are forced to get those now, they're under contract, but all the customers are complaining about the 460s saying they get sick, terrible withdrawals, etc... and that I should complain to the fda. That's all I can do. I personally am swapping to another pdp with Medicare should I can choose what pharmacy I use. That way I can go to a smaller, local pharmacy who isn't under contract with anybody and they order ehatever I ASK FOR...my doc writes the script and makes generics ok so it the only way I see that I can control what I put in my body. The 460s feel like poison.

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