Buprenorphine 8mg 460 (Top voted first)

I have been prescribed the 54 411 buprenorphine pills for about 7 years now. After my last doc visit I filled my script and they told me the same thing about the 54 411 not being available anymore and I got the 460's from them instead. My opinion...they SUCK! Feels like it has about 1/4 the amount of the 8mg it's supposed to have in it. I've been struggling all month with trying not to take more than I'm supposed to. I'm prescribed 1 8mg pill a day and have been happily taking that dose for about 3 years now down from 2 a day. Why this change has happened I have no idea but for me it's not a good thing at all. Besides the huge difference in price I have nothing good to say about the 460's. Does anyone know of a pharmacy that still carries the 54 411? I use CVS

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I don't know where you are from, but we had been hearing the same thing here in our area (Ohio, West Virginia, Penn.)... Read til the end, I do have the answer!... One pharmacist said they weren't sure why they hadn't been able to get a supply but he'd doubt they'd stop manufacturing them because, another said these 460 were the replacement, and two people even told me crazy stories like that some type of vehicle/vessel/train or whatever, was transporting the meds and had an accident and that was the reason, another saying they were on back-order until 7/17. But then I attempted to contact the Lab myself, to find out the real story. Another company, just closed on a 2.1 billion dollar buy of Roxane Laboratories (manufacturer of the white, round, 54 411 imprinted tablet buprenorphine) and that is the reason. I believe we are now being supplied with this new company's brand of buprenorphine from this point forward. Unfortunate, as most of us know, the Roxane tablets were much more effective with less side effects compared to other generics but this of course will not affect the other brands if you prefer one of those (Mylan, maker of M924 imprinted tablet; Hi-Tech, maker of small, round, arrow imprinted tablet, Teva, Akorn, etc.... Now the funny thing is, I keep seeing reviews stating that their new medicine (460) has a "minty, Suboxone-y taste" and that is not the case for mine. Also, one review in which the reviewer mentioned that taste, stated the name of the manufacturer, which is different than the manufacturer on the new white, round, 460 imprinted tablets I got. Because mine are DEFINITELY not minty. They do have an intense, and I mean intense, burning sensation while dissolving under the tongue. Incredibly more intense than any other. And that's only with a half dissolving at a time! Anyway, hope this information helps someone. I know I myself was frantically searching for answers, just hate being in the dark with my recovery when it comes to changes, as I'm sure others would agree.

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Oh here we go an online tough guy.. I have taken the 460s for 2 months and there not even close to the strength or quality of west wsrd/ Roxanne or activis for that matter. Not even close! Sounds like you work for sun labs to me. Adults are having a discussion here we will let you know if we need you. Thanks

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CVS is in the process of switching the brand of buprenorphine they stock to one manufactured by Sun Pharmaceuticals (a white pill with a 460 imprint on one side). They are TERRIBLE... burning sensation as the pill dissolves and subsequent upset stomach. We all need to call CVS's Customer Relations department at 844-239-6923. Otherwise we're all going to be stuck. Previously CVS dispensed buprenorphine made by Roxane (now merged into WestWard). These were a white pill with 54 411 imprint on one side. Call the Pharmaceuticals Supervisor for the Northeast Region at 401-665-6674 or call CVS Customer Relations. UPDATE: Sun Pharmaceuticals is a low-end manufacturer of generic meds based in India. The company has reportedly been operating under significant financial duress for some time and is currently doing all it can to cut production expenses!

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I am having the same problem...CVS gave me these from Sun and I am not sure about them. They don't seem as bad as Hi-Tech, but I hope Roxane comes back. I am calling their office tomorrow (they got bought last Fall by another company - Hikna or something)

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Call CVS Help Desk & report this. This brand is causing a lot of people trouble

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I don't know where u live but here in Ohio it's tuff to find any. But when you do it's usually the 54 411 or the Mylan 924 and at worst them actavis orange ones. But a friend of mine at our counseling meeting said he got the 460 u speak of... he said its not controlling his cravings. He looked into it and they are made in India of all places!! What I've seen about India has never been good, sewers running open in the streets, poverty, one of the worst living conditions by far. Real quick, I saw a documentary on India on their trains, when rolling on the tracks, if u have to use the restroom they lift a flap on the floor for you to take a dump and they keep rolling. So disturbing to me. The moral I'm getting to is if that's how they live how can they have quality meds?

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I just picked up the 460 round white subutex pill and almost spit it out immediately. It was burning the underside of my tongue. I am pregnant and feel sick enough as it is with constant nausea. I just decided to look up reviews and saw all these negative comments and it makes me furious that pharmaceutical companies can get away with so much. I am definitely calling CVS to complain about this new pill they are selling. I hope that anyone else who had the same side effects calls and complains too!

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I just received an email in response to my inquiry about West ward pharmacuticals continuing to supply the former Roxane labs buprenorphine. I was told that the final part of West ward aquiring Roxane labs took place in May and they will continue to supply this medication. She said it is now available and their is an ample supply right now and if CVS or whatever pharmacy you were getting Roxane from should now be able to again order it. It won't be called Roxane any longer I'd assume and probably west ward so hopefully we will be able to get it again because this sun brand Subutex is kinda crappy in my opinion. Ive been on subutex for 11 years and took the name brand for years so I've experienced the top quality and obviously the brand name was the best but Teva made a generic Subutex that was pretty close to it and it's on a long term back order now for a couple years. Roxane was the second best generic imo... I got stuck with hi tech a couple times years ago and they are very under dosed. These sun labs are are a little underdosed but they don't get ride of that craving for opiates like the other brands do and I've been having cravings for opiates for the first time in many years.

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Re: Mandy (# 12)

Swallowing the buprenorphine pill will yield approximately 30% efficacy as compared to making use of it sublingually.

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I've read many of these posts in my day and never felt the need to reply. However, two weeks ago I too received the sun pharma 460 subs. The month before I had to pay double at wally world for my 54 411's. They no longer take coupons... So, I was forced to go to cvs and didn't even think about what brand I was given until opening the bag in the parking lot because I was so preoccupied with not paying a fortune. Anyway, I took one and yes it has a terrible taste that does kinda burn if any of the pill gets on top of your tongue. But after two weeks im gunna say I can tell no difference as far as potency. Actually, they might be a hair stronger because I've noticed if I wish to have a regular daily bathroom visit I have to wait a few hours before taking my morning dose. With 54 411's it didn't matter. Also I felt like I took 54's more often. So yea, I said it, 460's might be better. I even wanted to determine they weren't, but as far as I can tell they're just as good, or equal.

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BRIAN 101

The online tuff guy is right, I can tell u that everyone I know likes the 460s better. So hes not trying to be tuff, hes just right in whaat hes saying,

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Absolutely, the same thing is happening to me now. Been on 54 411s or 8->s (arrows lol) for 4 years and had to swap my pdp for Medicare and now have to use "preferred pharmacies" and these preferred pharmacies are only buying the sun pharmaceutical 460s bc they are much cheaper than other makes..I was told this by the pharmacist at cvs in St marys, ga. They are forced to get those now, they're under contract, but all the customers are complaining about the 460s saying they get sick, terrible withdrawals, etc... and that I should complain to the fda. That's all I can do. I personally am swapping to another pdp with Medicare should I can choose what pharmacy I use. That way I can go to a smaller, local pharmacy who isn't under contract with anybody and they order ehatever I ASK FOR...my doc writes the script and makes generics ok so it the only way I see that I can control what I put in my body. The 460s feel like poison.

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Jamie, be careful- they tend to leave blisters in your mouth because of the acidity of the tablet. The company is out of India of all places, and from what I have read in other forums on here that were discussing the same topic, they have been in financial crisis and cutting costs any way they can. So apparently they don't care about the side effects of the product they are manufacturing. I hope you did not experience nausea or upset stomach like I have from those tablets. That would be horrible if you are pregnant. I also experienced extreme fatigue and depression the first week. Idk if the depression was a direct side effect (I did read 2 other people experienced this as well) or if it was just from me feeling so crappy & having no energy or motivation to do anything that made me depressed. It was a really terrible feeling as I have not had symptoms of depression in at least 2 years. I will admit I did begin to get used to them more, after about a week. All except for the burning of the tongue/mouth. I will, however, do everything I can to not have to take that brand again.

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Unfortunately I got a call from the girl at CVS today who does the ordering and was to,d the Roxanne westward brand is on back order again and that every other brand is too ( except Sun pharmacy) which I tried once and felt crappy all month. So guess I'm gonna be stuck on these for at least this month or until Roxanne west ward comes off back order again.. It's rediculous with this medication and the lack of quality generics or that the name brand was pulled. I'm going to ask my doctor if he will up my dose to help with the low quality and feeling I got that these were underdosed last time. I would switch to Suboxone strips temporarily if they didn't make me feel so horrible. It's always something with this medication I swear!

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Re: TKRaxTchYY120 (# 15)

So you really like the 460?? How do they make u feel? Mine doesn't have that strong nasty taste as a strip does. My 460 i got today there is no burning under the toung either. So idk what everyone is talking about!

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Re: Manders (# 19)

yup a sun agent lol he said same thing on my thread about the Rhodes generics which are at least 3x as stronger than even the 54 411 now owned by himka

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Re: KristenGfromGa (# 26)

I agree with you... you mentioned the 460 make most feel like they are sick and somewhat of a withdrawal feeling..if somehow you or someone could get together even from the other medschat forums on buprenorphine, look through them and find the ones that are only able to get the 460s..together get signatures and go to the head honcho to fight this battle. Because the chain Pharmacies cant, or let's say won't do..they are only workers and want their paychecks at the end of the week..all your chain Pharmacies at least in my area one has one brand. The next another..so I found out a long time ago to use a mom n pop pharmacy. They need your business way more than a big chain Pharmacies. I've never bumped into the few brands like sun, mylan. I've been on subutex since 2007 so its really surprising to me I never even bumped into either one... now in such you bvb all have heard about the new generic Rhodes, they are comparing it to original brand subutex and then teva comes out next. Between teva and Rhodes I was just told they only have one inactive ingredient difference between the two. So that makes Rhodes now even better than the hikma buprenorphine 54's....and I never thought one would ever come out so closely to teva..because everything else that followed has been junk..everyone has a comment about one of them because of the inactive ingredients in each one....not to mention that out of all the generics only 3 have a lower dose of buprenorphine in them. Most will say 8.64mgs of buprenorphine equivalent to 8mgs. So see that's another biggie when choosing your brand of subs. Look at the chart on Google first then choose one and try to get it..some are still listed just not available anymore.

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Try walgreens...I got the orange 8s from them recently in Georgia....cvs is swapping to 460s from Sun Pharmaceuticals. .look it up...they SUCK!!!!!! I also used walmart and got 54 411s....there's a small pharmacy here called Medicine Cabinet that has small 8s with arrows....hope this helps....

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Re: Manders (# 19)

i agree i got 12 today. Jus did 2mg n it feels jus as good if not BETTER no lie guys. I been on suboxone n tex for over 4 yrs. N these seem the same really. I jus hated the arrow 8s by hi tech. I actually feel an opioid warmth off these 460s n i feel great! No burn in nose or mouth. Is it possible ones getting these effects are either mentally tricking themselves. Or jus being how us addicts are. Me too lol. We want what we want when we want. Try to remember ritual is a huuuge part in addiction n e thing that changes up after using a trusted med for years, will make u anxious n freaky. Act like their good n thry will be. Im feeling fine rite now off 2mg

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Purdue makes a Buprenorphine product called Belbuca. It is a gel that is placed on the inside of your cheek. The benefit is that it is supposed to disintegrate (and thereby enter the bloodstream) within seconds. I have not tried it, but I wanted to. The most prescribed form of Buprenorphine is called Suboxone, a drug that is purported to help addicts go off of hard drugs. I tried it for pain, and since I don't do drugs, the additives were not a concern. But I could not keep anything down. Over six months I lost 50 pounds. My last hope was the Belbuca, but no one would prescribe it. In the meantime, I have concluded that I have some kind of allergy to the drug. I do believe it to be a useful pain med.

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