Nucynta Effects (Page 2)
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Hi there, I am currently taking oxys for my chronic pain, which work very well for me, but my dr has just given me a script for nucynta which is a fairly new drug. Just wondering if anyone has any experience with these and if they can give me any info regarding the effects, if any, side effects etc compared to oxys? Any help would be greatly appreciated. Thx in advance for ur time

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9

Hi. I am a pm patient with arachnoiditis, radiculitis, degenerative disk and facet disease. I know everyone is different as far as side effect but I was changed from 60mg of morhine sulfate a day to 300mg of nucynta er a day. I've had horrible migraines, nausea, tremors, and agitation with this med. I hate it. I've heard some have better luck with it than I have but this past month has been torture just trying to give it time to actually work but it's not. I have my one month checkup tomorrow and I have never looked forward to a dr visit more than I am now. The Dea is messing with everyones health by restricting meds especially to those of us that need it. They took me off of the fentanyl patch which worked wonders for my pain and helped with my sleep at night. They took me off of my Klonopin that helped with my anxiety and shakes I get when my spine is inflamed. Medication I had been on for 5-6years and had a better quality of life they now tell me isn't safe. How safe is it that I'm in do much pain my blood pressure is up and I can't do anything I need or want to do. How safe is it when you get to the point you do nothing but take up space!? I hope drs read this and undrstand what they're doing.. animals aren't allowed to suffer but humans are!?? I hope you stay with what you know helps you. Prayers for all who suffer with pain daily. Sorry for the rant....

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8

I have been taking it for 2 years they worked at first but they get Mr really high and I hate it and it doesn't work anymore .

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7

I have been taking Nucynta for about a month. I had a total knee replacement 10/21. have severe osteoarthritis and intolerance to most pain meds. Nucynta has worked very well. No nausea whatsoever. Please understand, I'm not downplaying others' nausea issues. Everyo,e reacts differently. That's why my surgeon tried it; I had the other knee replaced 5-6 years ago & couldn't keep anything down. I get good pain relief. Initial post surgery dose was 100 mg every 4-6 hours. I am down to 50 mg 2x day.

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6

I have been on Nucynta for 2 months & every time I take it I get nauseous & I've vomited a few times. It totally takes away my neuropathy, but doesn't totally relieve back pain. What bothers me is a new Dr came into my pain clinic & took me off my Percocet 10mg 3x a day because he claimed it wasn't in my system.... Due to this he came to the conclusion 1) I'm either taking them all the 1st few days 2) I'm selling them 3) my body isn't metabolizing them I am a nurse & find accusations insulting, I told him this on my 2nd visit & he didn't remember saying any of the above !! Oh and before he gave me Nucynta he wanted to give me Dilaudid but I refused. New laws, rules, regulations has Dr's doing all kinds of things & patients suffer.

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5

they are CRAP. I was on 15mg oxycidone x3 a day the pain clinic switched me to that carp, they do nothing, no relief.

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4

I have taken Nucynta for 2 yrs. for Occipital Neuralgia and chronic Nerve pain. It has really helped my pain unless I have a bad flare-up. I take it with Oxycotin extend release.

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3

Nucynta gives me 100% relief of my sciatic nerve pain. Unfortunately, the minute I take it, I have to lay down or I get nauseous. I call it the LSD/Reiki drug because my mind becomes very active and I have incredibly vivid thoughts. It also feels like I am getting Reiki because I can feel the drug going to work where I have nerve pain. It does not help me with any other type of pain. I am prescribed 4 doses a day. I take about 2 doses a month. I use xanax daily for muscle spasms. I feel no side effects the day after, just relief from having the pain diminished.

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I've been using this medication for over a year now with significant success. If your insurance will atleast partially cover it, its well worth trying for chronic pain, ESPECIALLY nerve related CP. As some anti depressants are now being used for nerve related CP, Nucynta gets roughly 40 percent of its action from Norephedrine reuptake inhibition. Its primary mechanism is still via the Opioid Mu receptors (the same ones hydrocodone and others affect) but the difference of adding NRI activity is very noticeable in terms of pain relief. It also makes the medication less "drowsy". Its considered less addictive than Oxycodone but still has a potential for abuse....with this being said this medication builds tolerance considerably slower than traditional narcotics, so the same dose you take now should work nearly as well a few months from now.

As for side effects, these mostly occur if you accidentally take a second dose miss timed (too close together) as the effects seem to ween down a bit slower than traditional narcotics due to its NRI activity. However, they are substantial in higher doses vs lower ones on almost a curve. For example, 75 mgs vs 150 (taken only at this dose for break through) the effects seem X4 instead of X2. At the 75 mg dose, I generally have few side effects and my cognitive abilities seem to be better than that of when I was prescribed traditional narcotics for my CP. One side effect is increased well being. However, occasionally this can mean a bit too much energy and over talkativeness. At 150 mg dose, I'll experience a total relief of pain but in exchange, ill experience potent anxiety and sometimes it'll feel like my chest/neck is tightening which makes it harder to breath. I believe this might just be a side effect of the increased anxiety. At the 150mg dose, moderately-mild "quick" hallucinations generally occur, such as hearing faint music that doesn't exist, corner of eye, distant items appear "differently" for a split second, not to mention surreal closed eye daydreaming that's very lucid. Again at the 50-75mg range, these two side effects shouldn't occur often and should be minimal if they do. Ultimately the pros far outweight the cons. Just watch your dosing, use only what you need, and you shouldn't have too many side effects.

Ohhhh one last thing. This medication WILL dehydrate you if you do not drink water adequate while under the medication.

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I haven't used it, but I can provide you with some basic information on it.

Nucynta contains the active ingredient Tapentadol, which is a centrally acting analgesic. It is related to opiates, so the side effects it can cause are very similar and may include: nausea, dizziness, constipation and dry mouth.

Learn more:

https:/­/­rxchat.com/­wiki/­Tapentadol/­

Is there any one that has used this and can provide more information?

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