I'm Afraid To Start Taking Bupropion With Tramadol
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I was just prescribe Bupropion 150mg 2x daily. I also take Tramadol which was prescribed by the same Dr. I'm afraid to start the Bupropion because of the drug interaction btwn the two. Should I be worried? Can I cut the tablets in half & take 75mg 2x daily?

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Re: David (# 1) Expand Referenced Message

I'm prescribed Xanax, Ativan and Lyrica. I thought it was an allergic reaction to the Lamotrigine I was originally trying to take but didn't know they were sold under the same names being generic and/or brand name.

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Re: Wynn (# 18) Expand Referenced Message

Prazosyn is very good for night terrors and night mares.

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Re: John j (# 26) Expand Referenced Message


I'm sorry to hear you're in pretty close to the same predicament as my husband. Our lives were turned upside-down because of these meds. My husband took these meds together, had a seizure while driving to work (witnessed by passers-by), tapped and pushed along a car with a mother and child inside, crossed a 5-lane highway, passed through a barbed-wire fence, and then hit a tall concrete culvert. He had an aortic dissection, GI tract removed, and a head injury-concussion and more. He probably won't ever be able to work or drive again, is on disability, and he's just in a lot worse shape than we ever expected at this age. All I can say is, it takes time, but the new normal gets better as you go along and re-adjust, and then you come to the point where you appreciate everything you have, because you realize you almost lost it all. Part of me is still angry that one doctor is not paying attention one day, coupled by a pharmacy that should probably have insisted on counseling and didn't, contributed to hard times for our family. It's very important to get the word out!

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Re: chalupa batman (# 9) Expand Referenced Message

400mg of tramadol is above the daily recommend dosage and that alone can cause seizures. Low dose tramadol in most people can be taken with wellbutrin.

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27

Had a grand-mal seizure while taking Wellbutrin and Ultram (time-released Tramadol). I had never had any seizures before in my life. Was very frightening, PLEASE be careful when taking these meds and keep Tramadol doses down to a minimum!

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26

My experience of seizures were the most frightening things I've ever had in my life I was fine then all of a sudden my sight went and luckily I managed to get into bed where the wife was then I came around about 4/5 days later in an hospital bed dribbling didn't know who was who and what had happened til I got told , that was my first major seizure then a few weeks later I was watching tv and got up to go out the kitchen to speak to my wife and as I got up I felt funny and within 20 seconds I had fell against the kitchen door so my wife pulled me to the settee and once again I woke up a few days later in hospital , I was aware of everything kind of but my reactions were very slow my speech was slow etc I've had more seizures aswell but none as big and wild as the 1st 2/3 , I've had MRI scans ecg,s constantly ct scan also a lot of other things which I can't really remember, I'm still under investigation now but I can ASSURE you they were caused by tramadol so please guys DONT TOUCH THEM or if your going to then 100% only take if really needed and NEVER take more than meant to but I would beg you not to touch them cos since my 1st one over a year ago my life is upside down . I can't work I had my license taken away and I'm constantly attending hospital

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25

I've been on 2 Tramadol 50's taken 3 times a day (total of 300mg of Tramadol a day) taken with a Wellbutrin 300XL for many years with zero problems but I'm also on seizure medications that are actually prescribed for my nerve and musculoskeletal pain. I'm on both Lyrica 300mg per day and 1200-1800 mg a day of Gabapentin each day so I think the fact that I take seizure meds for my pain this keeps my seizure threshold very low.

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24

Tramadol is a very dangerous opiate. They cause so many people to have a seizure. I had 4 seizures from taking tramadol. They're vile nasty things and whether taken as prescribed or not they should be banned, very dangerous things. They do what they're meant to but also do other things. So my advice is to stay well clear of them.

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23

I'm off them all now mate or at least I'm off the tramadol anyway. The doc said it was completely safe but there can be some side effects so I got a shot of the tramadol. The gps don't say a lot, they just throw boxes of tablets at you to cover it up instead of getting the problem fixed altogether. Instead of actually fixing what was wrong with me they just added more pills to mask the problem, which is just no good or at least it's ok for a while but then the meds have no effect. So where do you go from there - more stronger tabs.

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22

@bmoney, so is there an update? Are you doing okay with the tramadol added?

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21

So is there any update? Are you doing okay with the tramadol added?

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20

I am taking 400 mg Bupropion XR (200 mg/ea), 300-500 mg Gabapentin, 100 MG Lamictal a day.

Had some emotional trauma occur 4 months ago along with severe drug addiction (Opiates/Coke) in conjunction with a major car accident.

Combination has been a life-saver. I am drug-free, depression-free, and Bi-polar is under control.

Went to the ER today for insane back pain. Was prescribed 50 mg Tramadol. Will post results.

Lamictal and Gabapentin are anti-convulsants so I assume it will negate and synergize the symptoms and effects of the Bupropion (DNRI), and Tramadol (SNRI). Will let you know.

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19

My husband had a major car accident - was caused by a seizure -which we finally pinned down to a reaction between Tramadol and Wellbutrin. Beware.

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18

I've just started wellbutrin, 70mg, 1 in the morning(to increase gradually if I can tolerate it) yesterday for bipolar, severe depression, lack of energy and no will to get out of bed. I also have PTSD, multiple phobias and dependent personality disorder. I've been taking 50mg of Tramadol 4 X's a day for@5 years for Fibromyalgia. I started out taking 3, but last year upped to 4. I've been taking 37.5mg of Effexor XR for 3 years, the low dose because I have low tolerance for any meds. After taking the wellbutrin, I noticed a funny feeling that I didn't like at all and it scared me; sort of feeling like my chest was gonna explode and I felt like I was "losing it" and wouldn't be able to control my behavior. Also a headache and wanted to sleep all day, which I do many days in the past 6-7 months, which I attributed to bipolar depression&PTSD. I'm diabetic(mildly) and have Aortic Valve Disease. All these meds scare me, but I was able to deal with the depression symptoms with just the tramadol for several years. Then went through horrendous trauma and recall of child abuse, and I became disabled from everything. It all just seemed to snowball on me with not enough time to deal with each thing one at a time. I took myself off 300mg neurontin prescribed for diabetic neuropathy, and the Effexor, but started back on the Effexor after a couple months cuz I was staying in bed every day and could barely care for myself. My concern is with the wellbutrin. My psych is going to have me go off the Effexor gradually next month. I've searched every medical site trying to figure out what meds are the best for treating the nightmares&night terrors(I take temazepam for sleep), and rapid cycling bipolar, with the depression being the worst part of this. Should I cut the WB in half and wait it out?

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17

Both medications taken together lower the seizure threshold, and the effectiveness of Tramadol may be decreased by Bupropion.¡

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16

Good for you...neither does the warnings relate to bupropion proscribe the combination. In fact doctors commonly prescribe bupropion and SSRI's such as prozac together and tramadol is only a weak seratonin uptake inhibitor.

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15

i found out fro the pharacist tramadol and buporin is dengerou is raise the blood pressure

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14

well i found out that taking tramdol and welburtin can casue your pressure to rise to elevayed levels its dangerous.

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13

I broke with sores taking bupropion 200mg and tramadol 100mg, diagnosed with Stevens Johnson Syndrom, very frightning, can be fatal I was told.

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12

Hello , I had a seizure 3 weeks ago on Christmas night I was in hospital for 2 weeks I'm guessing it was from taking to many tramadol , is it safe to take just 2/4 a day just weeks after having a seizure do you know ? Thank you

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