Remeron Withdrawal
UpdatedI know someone who got off, but it was necessary, extremely unpleasant, and "ain’t over yet". Started the person at a good psychologist, twice weekly (beware of psychiatrists, over a period of 12 months, 5 of them took this person from HAMD-24 mildly depressed to almost clinically depressed). Didn't start tapering mirtazapine until calculated plasma levels of Cymbalta were essentially zero (about a month, using as little Ativan as possible, as needed - less than 5 mg once a day and not every day). From then until calculated blood plasma levels of mirtazapine were essentially nil took another 3 months, but it had to go too fast because of reacting to half the maximum mirtazapine dose with bad anxiety that continued until calculated blood plasma levels were very low (at that point more than 5 mg would have cranked up the anxiety). At 100% drug-free a complete physical was done to make sure there wasn’t a physical reason for the original depression. Withdrawal was very bad, lots of anxiety and worry, zero motivation, depression and insomnia; very much like I’ve seen severe alcohol withdrawal described. After 15 months 100% drug free (the first 3 months almost never without supervision), much of the old person is back, but motivation and worry are still a problem. Of course, the psychological roots of the original depression must still be dealt with. I can’t describe here the calculations, precautions and patience that are necessary.
How you fare will depend in part on your mental fortitude, how your body reacts to withdrawal, and the help you have. If you are capable of mentally maintaining an awareness that the bad feelings are caused by damage done to your brain, and nothing real in your environment, it might help; but it’s not easy for emotional types. Zoloft is an SSRI, so it affects mainly one type of receptor in the brain. Mirtazapine affects 3 different receptors, and affects the same one Zoloft does in ways that reinforce and counteract itself and Zoloft. I can’t imagine how the brain modifies itself in response to that combination, but it can’t be good considering the withdrawal effects. Anyway, don’t try doing this if you’re all alone. All psychoactive drugs affect thinking, judgment, reactions and memory; and withdrawal affects the brain like other psychoactive drugs; therefore, until you’re past some of it someone should be nearby nearly 24/7 to make sure you don’t hurt yourself doing something you don’t realize is stupid or dangerous.
I assume you were depressed. To counteract that, you were given something that is expected to give a temporary “highâ€, but that the brain compensates for by changing itself in such a way that you will be more depressed when you stop taking it. In other words, based on the science, antidepressants can’t be expected to work, so if they appear to, it might be a placebo effect of the “high†or side effects, or the person might just have gotten better, but it’s not the effect of the drug. Instead of researching the treatment, you assumed doctors knew what they were doing. If you had done your homework, you would have learned that “antidepressants†are just man-made uppers that aren’t as addictive as “recreational drugs†(they don’t make most people want more), but the dependence they create is just as bad. How would you react if a doctor wanted to prescribe cocaine for your depression? These are drugs not medicine; they don't kill pathogens, they alter your perception of symptoms.
Read this entire thread, you might something in it useful:
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