Metronidazole Lasting Side Effects (Page 66)

I have been taking this medication for 7 days and off of it since a week and still have severe side effects, abdominal cramps, severe headaches, dizziness, unsteadiness... How long is it expected to last? It was prescribed with Ciprofloxacin to me and I take Entrophen on a regular basis...

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Re: Erin (# 1300)

Hi Erin, Thank you so much for your response. I will look up the metronidazole toxicity and thiamine and look at the treatment. I am currently on 100 mg for a week or two and then I will increase the dose.! I hope I will tolerate the dose well and continue my improvement. As for now my neuropathy in legs and hands is very bad but I have to keep faith and fight. Thanks for your support and everything you do to help people out!!!

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Re: Betty (# 1297)

CNS = Central Nervous System = Brain, Spinal Cord mostly

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Re: Dennis (# 1302)

Thanks Dennis, that is exactly what I needed... will do my homework now.

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Re: Erin (# 1300)

Hi Erin, I found the web page about metronidazole toxicity and the thiamine and FLAGYL treatment. I red your suggested treatment for metronidazole toxicity and will try it. Hopefully, it can improve my symptoms overtime. I will update my health status here from time to time. Thank you so much for the research you have done to help people!!!!

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Re: Galina (# 1304)

FYI, Metronidazole is the generic name for Flagyl ® ... same thing.

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Re: Dennis (# 1305)

Hi Dennis, Have you red about Erin's treatment of metronidazole toxicity? She did a research and connected metronidazole/FLAGYL toxicity to thiamine deficiency. I read her blog on line about treatment and her own thiamine and magnesium treatment for metronidazole. I just started taking thiamine with ionic magnesium and hoping that it will help my neuropathy and joint pain. Have you tried thiamine and magnesium supplements? Also have you checked you vitamin B 1 level? I checked my B 1 level two months after I finished metronidazole and it was normal but I don’t know if it is normal level now, but I am planning to recheck it next week. How are you doing lately? Any improvements in health? I hope you are doing better!!!!

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Re: Galina (# 1306)

Thanks for the post Galina. Yes I have been on a Thiamine (B1) plus Magnesium regiment for the last 8 months with minor dosage tweaking along the way. At first I thought it helped but sadly it was a false positive. The difference is, I had a pre-existing condition apparently that was being evaluated by a neurologist for lower extremity issues at the same time I had a intestinal issue. These were two separate and unrelated conditions, a simple case of bad luck timing. There were no symptoms of the head at all, just in my lower left gut... Flagyl was the wrongly given for my intestinal issue by a young arrogant ER doctor even though he was warned up front that a carried a MedAlert card for antibiotic toxic sensitivity, that only two antibiotics were on my okay list, with Flagyl not one of them. I also told him I was being evaluated for an unknown neurologic condition of the brain. Nonetheless he ignored both concerns and insisted I take the Flagyl without protest nor any instructions in case I suffered from an adverse event. Within 3 days I was literally destroyed, it felt like a bomb went off in my head. Freaking out I called all my doctors and only one told me the truth, to STOP immediately as the damage is irreversible in those who have preexisting CNS diseases of the brain. I can say without any doubt... that yes, it is irreversible... sadly.

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Re: Dennis (# 1307)

Hi Dennis, Thank you for your response. It is good that you have been taking Thiamine and Magnesium supplements but it is sad that it has not helped you. I hope as you continue taking them, you may feel some improvements. I just started thiamine and magnesium and hope that it will lift some of my symptoms. I agree with you that the doctors so quick to give us antibiotics without even considering our preexisting condition. In my situation, i received a dose that was too high for me as I qualify for a children’s dose due to my weight. But of course, doctor wanted to load me with 2 strong antibiotics without any considerations. I lasted 11 days on these antibiotics and thought I was going to die. On the day I stopped metronidazole, I called the doctor office and told them about my symptoms and after that I was completely dropped. Dennis, after this experience, I don’t trust any doctors any more and research every drug that they prescribe to me or my husband and even my dog. I also going to get a MedAlert card and will carry with me. Dennis, I really hope you get better over time. Hang in there!!! I also feel a lot of anger and frustration as I feel that my life has been destroyed. The things I enjoyed doing are hard and even impossible to do nowadays. I want my health back!!!! I get very angry or hopeless from time to time but I have to keep faith and hope that one day I will get my life back. I am not done!!! Please, let’s keep faith and God will help us!!!!

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Note: We have removed a few posts from this thread because they were deemed non-clinical and off topic.

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Hi Dennis and other people who took metronidazole, I wanted to ask if anyone has experienced sharp eye pain, blurry vision, and gradual decrease in vision. When I finished the medication, my left side of head went numb and I started losing vision in my left eye. One week after that, I went to ER and they did a brain MRI and did not find anything wrong with my brain and sent me home. After that I visited my eye doctor twice to check my eyes and he did the scan of my eyes and did not find anything that causes my eye vision to continue deteriorate. I will see him again in January 2019 to check my left eye. I feel that my eye vision is slowly deteriorating and it is so scary. I recently started seeing my new doctor who is a Naturopatic doctor and he said that I may have MS but I told him that I had 2 MRIs on my brain and neck and spine and there is no lesions and my neurologist said that I don’t have MS. I don’t know what to think about my eye vision and would like to ask you guys if any of you experience similar symptoms. Thank you so much for your input!!!!

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Re: Galina (# 1310)

Within 24 hours after taking Flagyl, it was like a bomb had gone off in my head. My left eye went instantly dark, then I felt massive pressure behind each eye, then a pop! It instantaneously went from 20/20 to 20/2200 in one second flat. Besides that, I have severe neuropathy in my face and scalp. I also instantly lost all sense of balance and stability, then my ears started to scream out with siren-like tinnitus. MRI’s showed that my pre existing lesions had severely worsened, and my retinal macular had sevely distorted... I lost my vision, unable to drive, watch TV, read... etc... since then my life has been completely destroyed.

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Re: Dennis (# 1311)

Hi Dennis, Thank you for your reply. It is so bad that FLAGYL effected your health so badly. I wish that there is something that can help us to regain health or to improve to some point where we are not so debilitated by the side effects. I hope time and God will help us. I also have a lot of neuropathy in my feet, legs, and hands and some in my head. I think my nerves in the head got damaged. After I finished the medication, I felt zapping in my head and I had a lot of twitching in my body which have improved over 5 months. But now I have my feet and legs are burning very bad. At this point I don’t know how my vision will be changing over the time but I hope it will not go down any further. I hope I don’t have MS but my doctor doesn’t believe that the metronidazole can cause such a bad neurological symptoms. He said that a lot of people have MS and they don’t even know. I let him talk but I know that the medication caused me to have these horrible neuropathy and before this medication, I did not have any neuropsychological problems. Dennis, I hope you get better soon and will regain a better quality of life. Hang in there and thank you for your reply!!!

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Re: Dennis (# 1311)

Hello Dennis! I also have a neuropathy in my head, face, and burning sculp. I feel the nerve pain in my head every day and fortunately the intensity of the pain has lessened over the past 5 months but the pain doesn’t won’t to live my head completely. I used to have burning eyes and lips but for very short time. Dennis, has your facial and head neuropathy got any less over the 15 months? Also, do you have any neuropathy in your feet, legs, and hands? The peripheral neuropathy is very annoying and I hope it will go away with time. Thank you for your replies!!!!

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Yes, yes and no... my upper body neuropathy is both cyclical and fleeting, confined mostly to the face, head with occasional muscle weakness, pain and numbness down my right arm and hand. Other symptoms include, but are not limited to balance disorder, severe vision loss and eye pain, chronic migraine, severe tinnitus in both ears, chronic low grade fever, along with nausea, sweating, and fatigue etc etc.

But unlike most here, I had a pre-existing condition the administering physician ignored. This drug is specifically not for those with pre-existing CNS conditions especially diseases of the brain in any stage of development. Apparently it either accelerates, exacerbates, and/or permanently worsens such conditions... here's a link to the document:

[1] Metronidiazole: Flagyl Warning PDF

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Re: Dennis (# 1314)

Hello Dennis, Thank you for your reply. I can’t believe that your doctor gave you FLAGYL knowing that you had a preexisting CNS symptoms. I think that the doctors completely negligent when they prescribe these strong antibiotics such as FLAGYL, Cipro, and more. They completely ignore the patients current health status and other factors such as weight and prescribe the antibiotics just because it is convenient. Dennis, thank you for letting me know about your neuropathy. I am glad that at least you don’t have it in your lower body but it is still very debilitating condition. I hope you get relief from your symptoms over time and so do I. Have a good day and God bless you!

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Re: Galina (# 1315)

Thank you Galina! It means a lot to me. My prayers and warm hugs reach out to you as well.

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Re: Galina (# 1315)

FYI - One more thing Galina, there are many studies and case reports on peripheral neuropathy following Metronidazole use. I'm sure you have seen them but this case report struck me as rather peculiar on how quick the onset was.

[1] Rapid onset peripheral neuropathy: A rare complication of metronidazole

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Re: Dennis (# 1317)

Hello Dennis, Thank you so much for the article. It is very interesting and explains why my right calf started to burn on the 11th day of metronidazole. I had very intense burning sensation in my calf for 5-6 months. But now it is very mild thanks to God. But all of the sudden my both feet started to burn after 2-3 months after I finished the medication. My doctor doesn’t believe that it is metronidazole because my feet started to burn way after I finished the medication. Now I wanted to tell you interesting thing Dennis! I had 2 MRIs with gadolinium contrast before my feet started to burn. I had them 5 weeks apart. So recently I had a heavy metal 24 hour urine test done and it showed that I retained above the normal range amount of the gadolinium in my system. Gadolinium is used in an MRI contrast to enchance the clarity of the image, however gadolinium is a heavy metal and is very toxic to the body. I believe that gadolinium that I retained caused or compounded my neuropathy in my feet. Now I will be doing a chelation therapy once a week to remove the gas as much as possible from my body. Also, people excrete this metal naturally through the urine and sweating. So it does leaves the body over time. In my case, I will try the IV infusions to see if it helps me with the burning symptoms. I wanted to mention to you about the use of an MRI with contrast because it is not as safe as our doctors such as neurologists say. So if you need to have a MRI, try to avoid using a contrast injection or have it no more that once a year or less. Try to space it far from each other so your body can excrete it and don’t accumulate the burden that can cause the symptoms. If you look up a Gadolinium Toxicity on line, you will see that it can cause neurological symptoms as well as joint and bone pain, head aches, vision problems and more. I just want you to be aware of the problems with the use of an MRI contrasts. In my case, I am not sure whether the MRI contrast caused my new symptoms or it is metronidazole, but I will never use these two in my life again. I asked my neurologist about the safety of the MRI contrast and she said that people do retain the gadolinium but some people don’t have any symptoms of sickness and some do have. So please be careful using the MRI contrast in the future!!! Dennis, I will show your article to my Naturopatic doctor and see what he has to say. He doesn’t know much about metronidazole causing neurological symptoms. Dennis, I hope you feel better today and thank you for your research!!!

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Re: Galina (# 1318)

thanks for this info... it reminded me that I see a naturopath that does a foot soak that actually pulls heavy metals and other stuff out of your body.. see if you can find on locally. and next time I have an appt I'm going to ask for another treatment.. thanks

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Re: Betty (# 1319)

Hello Betty, Thanknyou for this information about the chelation of heavy metals by using a foot soak. I never heard of this method before. Do you know what medication is used in this foot soak procedure? Have you try this before? I will see my Naturopatic doctor this Thursday and ask him about a foot soak for heavy metals as an addition to my IV infusion, but if you can tell me the name for this foot soak, it would be very helpful. Thank you, Betty and I hope you are doing well and your symptoms are decreasing.

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