Extreme Fatigue On Xarelto (Top voted first)

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Hello,

Hope someone can help. I've been hitting a wall of fatigue everyday about 1pm to the point where I need to take a 2 hour nap when my daughter is napping and its painful to wake up even after that. I take Xarelto everyday with dinner to treat a DVT. I've been on it 4 months. Is this a known side effect? I tested my theory when I started to realize this began after taking Xarelto and skipped a dose one evening. The following day I didn't need a nap and didnt have that same debilitating exhaustion. I'm only 34 this is no time to be this tired after a full nights sleep! It feels like a crash, an unnatural exhaustion. Thanks!

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18

Ive been on xarelto for 14 months from a PE and due to a autoimmune that makes my blood clot, so i have to be on it for life. My first 6 months on this med was amazing, i had so much energy i chalked it up to never having correct blood flow from my auto-immune. But after the first 6 months i now feel extreme fatigue, joint and muscle aches like you wouldn't believe, headaches too. As you may know we are not allowed to take anti-inflammatory meds so i have no way to ease my pain and i am so frustrated by this that i want to get off xarelto even though dr.s say no. Can anyone relate?

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4

I just started taking Xarelto myself about 3 weeks ago and I am always exhausted. I'll wake up feeling exhausted, but by early afternoon I'm really tired and need to sit down and relax. It's almost like a mild flu-ish feeling. I too feel like falling asleep around 7 or 8 at night and many time during the day as well - I just can't seem to stay awake.

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3

This is my biggest complaint. I am 36 years old and I am so exhausted. My eyes just want to close. I take my pill at 9 am every day and thought about switching to evening to see if it would help. It's very frustrating because I am an active person with no energy.

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14

My husband is on Xarelto and he sleeps 16 - 18 hours out of 24. Exhausted even though he does nothing, he has AFIB. he gets really weak also even shaving and has to sit, get up do a little more. So worried. Any updates? Thanks

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16

same results. Sometimes the effects are worse than the problem. I have also experienced severe fatigue. Had to quit work. I could sleep all afternoon if I lay down. very frustrating. My internist suggested I remain on Xarelto for life as I developed an unprovoked DVT and small PE> She is not that keen on letting me off as I have been on it 6 months and feels I should be on for life. I need to make a decision on quality of life

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9

hi, I have a pe and started xarelto 2 x a day 1 week ago, by 3 pm I can barely
drive home from work and by my second dose at dinner time I'm ready for
bed at 8, I tell everyone when I sleep at nite it must be as close to being dead
as you can get, I am just that tired and sleep that sound. The fatigue is unreal
I can't wait for my 6 months to be up.

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2

I have the same problem. I started taking Xarelto just over a week ago. I broke my hip in an accident and need to be on a blood thinner for another 3 weeks. I normally sleep 4-6 hours a day. I now sleep around 12 hours a day. It is very frustrating.

I can be having a conversation with someone and an overwhelming tired feeling washes over me and I end up taking a 3 hour nap.

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8

It does getter better. I switched to evenings and this helped tremendously. (about 8pm every night) I took it for 7 months and finally stopped last week. I've noticed a difference already in my energy level. Hope you feel better soon!

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15

Katie were you able to get off xarelto in July? Either way, how are you feeling now?

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22

After a prior comment (see Beth above), I wanted to add that I experienced both extreme fatigue and severe depression when I took Xarelto. Both of these symptoms were resolved when I changed to another blood thinner. I am making this comment in case it helps validate the symptoms experienced by others. The medicine may have different side effects for different patients, of course, but I wanted to share my experience.

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20

Yes, I have been on Xarelto and experienced extreme fatigue. In my case, we were able to switch to another blood thinner, Lovanox, which in my case is daily and in shot form. While I do not like the shot it is preferred over extreme fatigue. Ask your physician about possible other choices and good luck!

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6

Since taking Xeralto I have had to same problem, seems like I am tired all the time. Also have gained weight after maintaining the same weight for years. Glad to know I am not the only one having this problem.

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10

Hey I have been taking this for two days due to a blood clot in my breast I'm a 34 year old female and very active at the gym, I work full time and am finding I'm so exhausted it's horrible also feeling really dehydrated

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5

Have you told your doctor? What do they say?

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12

I started taking Xarelto after 3 blood clots appeared in my lungs after having surgery for 3 ankle fractures in January 2015. I've noticed extreme fatigue and a rise in my blood sugar levels as well as a rise in my blood pressure. I am due to stop in July of 2015 and truly hope I get back to normal. I think the side effects of this drug are awful. I'll let you know how things turn out when I stop taking this drug.

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17

My husband is now taking this around 8pm each night. The fatigue during the day has been reduced greatly and he has been able to continue working pretty much full time. Wondering if Vit B shots are safe with this. We still are hoping this med is not life long for him. Many questions will be asked of the dr at his next checkup!

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7

Been on xarelto about four weeks was a very active person.I'm 51 and been in training in mma for two years,now I do good to make it eight hrs of work this i a terrible side effect the fatigue is mind boggling hope it improves got five more months.

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23

I just changed to Eliquis, no side effects. Xeralto was horrible. Ask your doc to change.
Also talk with your pharmacist, mine very helpful. Good luck

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26

I've been on xarelto for 17 months now for a dvt in right leg.so far I gained over 25 pounds every muscle in my body hurts. Now im experience brain fog / low lying headaches and severe calf cramps .this drug is ruining my life

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27

Hi Beth and everyone else in this post, I have cystic fibrosis and had a blood clot in my lung in 2014 and I'm told I will be on blood thinners for life. I have been on Xarelto since last February and I feel like I am dying. My quality-of-life is nonexistent… I have to struggle to keep up with basic personal hygiene at this point. I have gained 20 pounds it doesn't matter how much rest I get I still feel exhausted – I wake up feeling like there is dirt in my mouth. Dr. say fatigue is not likely caused by Xarelto and I likely just have a mild case of depression or seasonal affective disorder. I am desperate and I feel so angry that the word fatigue is used because this feels like my body is failing.

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