Empirin Compound

4 Replies Updated



Conversation Starter

ALG Says:


Empirin was a product of Burroughs Wellcome & Co. An effective over-the-counter pain reliever. It was a mixture (compound) of equal amounts of phenacetin and aspirin plus some caffeine. The inclusion of caffeine acts as an anti-depression agent. In the 1960s, this protected formula was sold to Bristol Meyers who marketed it (famously) as Excedrin. In 1983, the FDA banned phenacetin after studies revealed that was harmful to the kidneys and linked to cancer. Following the FDA's ruling, the 'Excedrin' formula was modified by replacing phenacetin with acetaminophen. In 2005, Bristol Meyers sold the formula and name to Novartis who continues to produce and market it as Excedrin. The same "Excedrin" formula is also available from equivalent labels - usually at lower cost. As with all over-the-counter pain relievers, learn the ingredients and follow the instructions that are on the label. ALG-July 2014



Showing Replies 1 - 4 of 4 RSS Feed


Page of 1     Sorted By:
1
David Says:

Hey ALG,

Thanks for the background info on Empirin. It's hard to really know what the dangers are with any given medication until they come out with these studies (often decades later) saying that it can cause this or that as an uncommon but deadly side effect. Hopefully as justice is served for those unfortunate patients who took phenacetin believing that it was safe, the legal rewards will help offset whatever damage or cancer this substance brought about.

Makes me wonder if the new Excedrin will also have similar claims made against it 10 years from now (starting with acetaminophen leading to liver failure)?

REPLYSHAREREPORT
Was this helpful?     1     0  
2
ALG Says:

In the 1990s, Tylenol (Acetaminophen) was heavily promoted as a safe alternative to aspirin. Hospital studies were cited, etc. and supposedly, hospitals left and right were dropping aspirin in favor of Tylenol as a pain reliever for their patients. The primary reason, Acetaminophen doesn't irritate stomach lining as aspirin can. That was then, in the past few years the medical world has been warning users about the serious side effects from using Acetaminophen. Protracted use of Tylenol, and other brands of Acetaminophen, has been shown to cause serious liver damage. In other words, it's worse that taking Aspirin. The big problem with any "pain reliever" is taking too much in one day and/or taking too much over a period of days, etc. Any non-prescription pain reliever taken in minimal amounts for short periods is considered safe. ALG Oct2014

REPLYSHAREREPORT
Was this helpful?     0     0  
3
Anonamous Says:

I believe that APC powder had the same ingredients as the original Empirin, i.e., aspirin phenacetin and caffeine.

REPLYSHAREREPORT
Was this helpful?     0     0  
4
Dave Says:
via mobile

Empirin Coumpound was a combination of aspirain, phenacetin and caffeine. It was used for decades OTC and by Rx combined with codeine or phenobarbital. All formulations were effective. By the way, the kidney toxicity was called analgesic nephropathy and was thought to be a problem in combination and in high doses. People who developed nephropathy generally abused the OTC product somtimes taking 50-100 tablets per day for years. In the 40's & 50's, modern anti-inflamatody drugs were not available for chronic conditions like OA & RA

REPLYSHAREREPORT
Was this helpful?     1     0  


Viewing page 1 of 1     Reply


More Discussions:

found bottle empirin compound
found a empty old bottle worth any thing ## @westly, An empty bottle is an empty bottle... I'd probably throw it awa... 3 replies
compounding oxycodone and tylenol liquid
Can oxycodone and tylenol be compounded together in a liquid form? ## Hi Deb, From what I understand, both medications i... 2 replies
compound pharmacy in florida with dilaudid
can not get my didludid filled after walgreens did it last month and refused this month due to good faith dispensing?? #... 2 replies
Compound takes 3 plus days to deliver
Please explain to me why your company took at least 3 plus days to deliver the compounding base formula of Fentanyl to t... 2 replies
Compounded oxycodone capsules with no imprinting
I was given a blue and white capsule with white powder in it with NO IMPRINTING AT ALL on it and said it was a 30mg oxyc... 1 reply
compounding pharmacy hydrocodone 20
I am being prescribed compounded hydrocodone 20mg, the pharmacy I have been using went way up on price, 2 times. Where i... 1 reply
compounding pharmacy
I am looking for a doctor to perscribe a compounding safer persciption for someone with schizophrenia, The medicines hav... 1 reply
compound h 86
Supposed to be a medication that kills cancer cells, but not thegood cells. ## Hi Mong, There are actually several other... 1 reply
compound roxycodine 30
it is in a solid blue capsule with brown powder in it ## Hey I have a blue capsule pill with brown powder inside of it? ... 1 reply
compound hormone
C_TRIEST 2.5/PROG 100MG LOZITAB ## My ob/gyn just started me on C-Triest 2.25/Prog 100 mg but there is no info included ... 1 reply


Post a Reply

No registration needed.
Simply fill out the form below.

 *

 *


 Optional, stays hidden.
Get notified when a reply is posted here.




4) Text Verification: *
Prevents SPAM.

Click here to show the question



This form will be submitted securely


TRUSTe

Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use and Privacy Policy. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.


Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 7 June 2016.

We are committed to your privacy.

Copyright © 2005-2019 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA