Hydrocodone Ip 115

Maria Says:

My pharmacy just switched to the Avkare brand of Norco 7.5. The imprint on it is IP 115. I feel like these do not work at all for me. I would like to know if anyone else that are on these or ever have been on them can let me know how it works/worked for them.

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Verwon Says:

Hello, Maria! How are you? Has there been any change?

As permitted by the Hatch-Waxman Act of 1984, there can be fluctuations in generic medications. They are allowed to differ in the amount of the active ingredients by as much as plus or minus 20% of what's in the name brand, additionally, they do not have to measure against each other, only against the name brand.

Thus it is possible that this one is a little lower than the prior one you were taking. However, since the differences are slight, most people adjust within a week, or so.

The FDA warns that this medication carries the risk of being habit forming and may cause side effects, such as nausea, dizziness, headache, dry mouth, and constipation.

I haven't had any problems with their products, but I can only speak for myself, and it's been years since I took their Norco.

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Julie Says:

Hi Maria, I was also taking the same madication as you and was given the IP 115 this time around. I agree that it just doesn't seem to work as good on the pain, not sure what the difference is since the bottle reads the same dosage as my last prescription. I kind of thought it was a mind over matter thing for me since it's a different looking pill then I read your statement, just wondering how you are doing now with them since it's been a while.?

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Maria Says:

I told the pharmacy tech that I hated these ones and she said she hears that from people a lot. They still don't work for me so if my pharmacy can't get a different brand then I will go elsewhere

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Julie Says:

So it's the pharmacy and not the doctor that decided on this medicine? I guess I'm stuck with this crap for at least the next month right? Ugh they do not work for me and I feel so tired all the time.

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Maria Says:

At my pharmacy they said it's what their supplier has that they can get in. I might see if my doctor can write on my next script "no Amneal/AvKare".

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Julie Says:

I will definitely do the same. Thank you for your opinion, I know now that it's not just my imagination. Thanks, best of luck to you.

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Maria Says:

Thanks. Best of luck to you to. Hope you find something that works.

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Sharon Says:

Hi Julie, I believe that if u ask the pharmacist before they fill it they can get a different generic but it depends on the pharmacy and the script. Ask ahead of time. I know the type of Rx is different but for my stop smoking patches they were able to give me a different generic bc this first patch irritated my arm. It's kind of the same thing if they aren't effective for you then they should be able to give u a different generic.

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Chad K Says:

You are definitely not imagining this nor are you "growing tolerant" of your med. The problem you have, like almost everyone on pain meds has had in the last year or two, is the DEA / FDA letting them sneak in unstudied clinical trials on these "anti-abuse" additives, and laws that govern quality all at the same time. I will briefly explain; I am a masters level chemical engineer with a minor in biochemistry and polymers so this is all factual information based on over a year of personal research and lab tests. If you would like sources, or to see some of the pictures/results of my tests on these pills please ask; I think people need to know the real problem.

First off, generics are now allowed to vary by 20% coming in with the schedule-II change, it was more readily taken advantage of by the greedy pharma companies like norco. They bought out many smaller companies, a study done by a team at Vanderbilt in 2016 found on average the norco 10mg pills contained only 8.4 mg of hydro (within 20% being above 8). Does anyone else feel ripped off yet? Isn't a 20% tolerance extreme when it governs a medication? Why only pain meds? A 20% deviation in BP med or insulin could be deadly, why not deviate above as well? If you only take approx 8 in a 10, every 4 pills made the savings, makes a 5th for free. Scale this up to nationwide sales, that's millions more for them at our expense. If you get 60 pills, in reality you're only getting roughly 48 10mg equivalents; you were just shorted 18% of your prescription.

Next: hydro is salted with bitartrate, where 98% of other meds are simple hydrochloride salts. This matters because HCl is very little weight added, where bitartrate is a 4 carbon, di-carbonyl-di-hydroxyl sugar acid. In simple terms, the hcl is less than 35 g, but the sugar acid with its 6 oxygens and large structure weighs in at 149 g. This is a THIRD of the hydro weight, so saying 10 mg of hydrocodone bitartrate is actually saying 3.4g bitar and 6.6g hydro. Now apply this to the already lessened generic of 8.4, we're now at 5.6 mg hydrocodone in a "10" mg pill....now do you feel shorted? That's almost half!

Last and most important is the new anti-abuse additives. It used to be just hydrocodone, acetaminophen, and a bit of necessary but harmless fillers like silicon dioxide, possibly a touch of starch (starch is a complex sugar such as in potatoes) which is digestible. Now, up to 8 man-made polymers are added to prevent "abuse". That's great... In a way...laws cant outlaw people from making bad decisions. For the ones still at it, these new water-soluble plastics are completely unable to be broken down by our bodies and will prove MUCH more fatal in the blood than the act alone prior to this act to "save the abusers". PEO is in many pills now, PE (polyethylene) is the plastic coke bottles are made of. Povidone and crospovidone are in most and will be in all by 2019 if no one objects. These are pretty, shortened names for some nasty synthetic polymers designed specifically not to release the med into a water solution preventing inj... They dont tell you this also means that it prevents proper absorption, not to mention "cross-linked polyvinylpyrrolodone" (the real name of crospovidone doesnt sound as harmless) is a rubberized form of povidone (polyvinylpyrrolidone) and is present along with the water-soluble un-rubberized form, along with modified cellulose (hypermellose), stearic acid (nice way of saying soap), and several others.

I've already written much too much, but I separated, purified, and analyzed most of these polymers myself. The results were horrifying. Piles of goo resembling elmer's glue, sticky slimy substances that would be extremely difficult to pass through the gut, unsoluble crospov. ball of slimy rubber, glassy-brittle plastic crystals of PEO, ALL of which are completely unable to be processed by our bodies and block absorption. I have pictures and great in-depth detail of this matter if anyone cares to learn more. If just one person hears the truth, all my dedicated time was worth it. I hope this clarified some of your concern. Bottom line, this control has gotten out of hand when our meds are cut and health patients are actually put at risk for some companies to make a little extra money.

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Maggie Says:

I too just got my script and it had lp 115. Yes, they don't work! I had to Google to see what l was taking even though my script said Hydrocodone / Acetaminophen 7.5-325. Wondering if the hospital pharmacy can change them?

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Eric Says:

Doesn't seem to kill the pain as good as the ones before but the search says the potency is the same.

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SSArt98 Says:

Re: Chad K (# 9) Expand Referenced Message

I'm very interested in your work on this subject and would like to see and read more, if possible.

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Jason Says:

Re: Chad K (# 9) Expand Referenced Message

Holy crap, who are they helping doing this? I can tell from taking pain meds for a few yrs due to back problems that the hydrocodone doesn't work as well as it used to and something has changed with the meds.

I've been told it's because the body builds tolerance, bla, bla, bla.....But this info proves it's the meds that have changed for the worse.

What can us that take these meds for relief do about it and stop these pharmacy companies and the dea or whomever is letting this happen?

It's us the ones who go to the dr and play by the rules who are getting screwed. All because the street dope heads.... it makes me sick and disgusted.

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No name Says:

These pills are garbage! They make you sick to your syomach!

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Sheri Says:

Thank you Chad K (#9) for your detailed comment. Had no idea there could be such variation in prescribed medications. Really makes me angry - I wouldn't be taking this stuff if I wasn't in pain! Now in addition to still being in pain because this med is ineffective, I'm having the side effects of nausea and headache!

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Sheduck Says:

Re: Chad K (# 9) Expand Referenced Message

Can you send me more info so I can fight with my pharmacy. I am in so much pain just because of the switch.

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Cal Says:

I took the IP 115 for pain from wisdom teeth removal at around 12 pm, now im in a large amount of pain and i cant take any pain meds like the 800mg of ibuprofen prescription until 8 o’clock but the pain is unbearable and ice packs dont help at all, im trying to find out if it would be safe for me to take another hydrocodone IP 115 now, at approximately 6 oclock, please respond quick if you know!

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Richardson Says:

I think they are creating 'addicts' by making them take pills over the outlined dose. This is ridiculous. I'm glad I'm not the only one who feels this way though.

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Susie Says:

They’re worthless. And make you TIRED!!!!!!
Still have pain. Ask for a change is my advice.

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Lisa Says:

Re: Chad K (# 9) Expand Referenced Message

Hi Chad,

I would like to see your research if possible please. Your research was phenomenal and I would love to read more.


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Stephanie Says:

Re: Chad K (# 9) Expand Referenced Message

I would like to communicate. Just changed from Amneal to AP KARE and the first one I took seemed like the pain was still pretty much there, maybe slightly better, But DAMN LITTLE. NOT HAPPY.

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What is the world coming 2 Says:

Re: Chad K (# 9) Expand Referenced Message

So this is why everyone is suffering because of their greed..But sound like they are giving people more problems then helping..I guess that’s why people overdosing on all the other stuff trying to get relief..Thank you for sharing I would like to know more..I guess I will just put my norco in the trash ???..

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Michelle Says:

Re: Chad K (# 9) Expand Referenced Message

Thank you for the information. I never knew this till now

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JanK Says:

No not for me either!! They're junk!!! It's like they're giving us something else to to make us believe it's what we're precribed like it's mind over matter, damn idiots, like the pain's going to go away or something!!!

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Liz Says:

HI all. So I wanted to answer this because 3 years after the original post and I experienced what I thought was a overdose taking 1/2 a pill at 12 pm then 9 hours later taking another 1/2. It was Amneal and I have been on this for a long time for chronic pain and its the first time I have ever had an issue. I was LOOPY, I mean so loopy my speech was slurred, splitting headache and gut rot and nausea. Now I know what nausea and slight headache from a narcotic is and this WAS NOT the same. My heart rate wouldnt go down for an hour and truly thought I was dying. No it wasnt withdrawl either, the day before I tried to take my normal doses and the more I took them on schedule the worst the symptoms got, It felt like I was putting poison in my body every time and unlike a narcotic effects these horrific symptoms took about 15 minutes to kick in. Anyone else deal with this on Amneal??

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shelly Says:

i have been through a situation like this before and i believe if you tell your dr that this medicine isn't working now because it was switched then they will try one more different and then u can ask your insurance company to put u back on the original medicine and they will depending on your insurance company .

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Lou Says:

Re: Chad K (# 9) Expand Referenced Message

I was wondering why half of these pills did nothing to help with my pain. For the past few months I've been saying half of them were duds.

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cliff j Says:

ThunderHeart (# 64) —There are several points in your post that I agree with but given the so called “opioid crisis” and the climate of this Nation we unfortunately are where we are. I had always went to Walgreens to fill my scripts. I was always given the Watson brands and I never had a complaint in many years. In January of 2018 I went to fill. The script and they were out and sent me to a nearby sister pharmacy where, unknown to me, they filled my script with the Amneal brand and it was awful. I changed Pharmacies the next month and, while the product is better, it is still not very good. It was brought to my attention that all of the opioid manufacturers changed their formulation to try and remove the “high” that a person might get but in so doing they removed most of the pain killing properties at the same time. It is not where it is made so much as what is being manufactured. If you make crap then that is what you get. The Pharmacies do not care. In fact they would be just as happy if you went someplace else. One less pain patient for them to worry about. If Pharmacies were intentionally trying to run off customers they could not do a better job.

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ThunderHeart Says:

Re: cliff j (# 63) Expand Referenced Message

You have that right Cliff!!

I cant start a forum so I hope you dont mind if I jump in here. I WILL be reporting this to the FDA tomorrow. AMNEAL COMPANY drugs should NOT BE ALLOWED IN THE UNITED STATES!! Why they are allowed to dump their lousy medicines to our pharmacies is beyond me. Their drugs are pure s***!! And they know it while laughing all the way to the bank at how stupid the U.S. is in not having the FDA monitor the making of medicine. These are my experiences with Amneal made medicines- In New Mexico I had a prescription for hydrocodone. I went to a pharmacy near my home. I got the Ambeal IP s***. I noticed right away it DID NOT RELIEVE MY PAIN. But i had severe reactions that put me in the ER. Vomiting, diarrhea, itching, sneezing headache, cold sweats. I took that crap back to the pharmacy. They could not take it. Went to my doc for a new script and got my medicine from Smiths. No problem with the Mallinckrodt, even though it is weak. 2nd experience with Amneal s***- I picked up xanax from a Walgreens in Reno. Xanax normally gets me out of panic attacks with no side effects. Once again I had severe reactions. It DID NOT WORK. It made me get muscle spasms and twitches. Along with itching and more panicky feelings. I looked at the manufacturer and sure enough it was Amneal s*** again. We back to doc and got a new script and went back to Smiths. 3rd event- tonight I broke open a gabapentin capsule. I powder my medicines. The capsule was empty. Read the label and it is made by Amneal. No surprise.
Walgreens is guilty of dispensing Amneal products. I found that out the hard way. I raised a stink with them and told them to stop dispensing this garbage!! Amneal is pure crap!! This company needs to be stopped from selling its s*** medicine here. It is made in India. The most polluted and dirty countries. I'm contacting the FDA once again. Beware people. Ask your pharmacists before you pick up your meds who the manufacturer is and refuse it if it's made by Amneal. Get another brand. The generics the insurance companies are forcing on us these days are garbage and I am pissed!!! INSURANCE COMPANIES DID NOT GO TO MEDICAL SCHOOL!! They have no right to force generic garbage on us!!

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cliff j Says:

Re: Mejane (# 57) Expand Referenced Message

The people who want to come down on the so called "opioid abuse" cannot get the REAL street addicts so it is just easier to attack the Chronic Pain patients and that way they can say "Look! We are doing something". Actually they are prosecuting the innocent because they cannot get the real culprits.

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