Apotex Vs Pliva Trazodone (Page 5) (Top voted first)

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My pharmacy just switched manufacturers of my prescription trazodone 50mg. It used to be made by apotex now it is pliva and I am finding that the new pills are having little to no effect and I am starting to suffer discontinuation syndrome. I talked to my pharmacist and doctor and neither one could tell me what was causing this. I was just wondering if there is anyone out there who could shed some light on the subject.

103 Replies (6 Pages)

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60

Yes I totally agree with you. I recently received a refill of trazodone manufactured by Pliva/Teva. Didn't think much at first but after a while I noticed the med was no longer working. I was only able to get few hrs sleep with Pliva, I then went back to Trazodone by Qualitestand, voila, meds working again!!!

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62

I called the manufacturer "APOTEX" in September and was told by them that at the time Trazodone was out of stock. The gave me a tentative date of November but as Ive commented before, it has happened now 3 times and I have caved in and am taking the Pliva/Teva brand. No, it does not work as well.... at first....but I have now gotten used to it and it is fine. At least I dont have to worry about it anymore. Apotex just isnt reliable and I would rather have consistency.

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63

My email reply today from them stated they are out and they have no release date.
They advised me to check all pharmacies in my area.

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64

I recently switched from Walgreen's Pharmacy toRiteAid. My first refill of Trazadone didn't seem to help me at all as a sleeping aid. As a matter of fact, when I was able to sleep in short spurts, I had weird dreams. After about 3 nights of this, I figured out it had to be the Trazadone. I read the imprint on the pill, which was Pliva. I researched the manufacturer and discovered others are having the same problem with Pliva. It is my hope that my doctor can prescribe another refill with a different manufacturer. I need sleep!

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65

Hey Becky, What you describe as your problem with the Pliva brand of Trazodone is very common. Having said that.. I went through the same thing numerous times through the years and was switched back and forth till I would finally get something other than Pliva. I ended up with many many sleepless and anxious nights over it. Finally last May after it happening for the 4th or 5th time I had enough. Pliva is the most popular brand, the one most pharmacies are stocking. Thank Big Pharma for that one. I bit the bullet and stayed on the brand that I could get consistantly. It took about a month of disturbed sleep but now it is working just like I want it to. Sorry you are going through this but they have us over a barrel.

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66

Hi there, i have been taking 450mg of trazadone at night & 100mg every morning as my depression was very severe & i spent 10 months in a psychiatric unit. I also take amitriptyline 225mg at night plus 400mg of quetiapine & 300mg of pregabalin in the morning & at night. I also take clonazepam 3 times a day. I am very worried about trazadone as my usual chemist have told me there is a manufacturing problem with trazadone. I have enough left for 28 days but if by then no chemists have them can you imagine the withdrawal symptoms i will go through. I have been on this high dose for 3 year's. I don't know a way of talking to the manufactures & despite spending a couple of days on my iPad searching i still can't find out if they are being taken off the market or is a temporary thing. I would appreciate any information as i am sick with worry. Thankyou. My name is Mandy.

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67

Mandy, maybe the brand you were taking will not be available but there is more than one manufacturer of Trazodone. Actually I looked on my bottle of Trazodone for the manufacturer and then called them myself. You can do that too.

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69

Can anyone tell me where I can get desyrel brand name trazodone in the world? Please the generics are garbage. I was on oleptro and it was a dream. It was discontinued. I need brand only. It must be available somewhere still. Please help desperate!

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70

The manufacturer of the brand name drug Deseryl has stopped production of this drug

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71

I know this but it is still available over seas.

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72

Marco, which drug store are you able to find Apotex at? I just had CVS try to special order it twice and fail. I'm not sure if they don't know what they're doing or if it's out of stock. Guess I'll start calling around AGAIN...

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73

I recently called Apotex and was told it is out of stock....they should have it in the middle of April

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75

Stefanie,
Sorry it took me so long to respond. I hope you were successful.

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78

I am experiencing the same problem with the Pliva brand. I'm only able to get a few hours sleep. Anyone have any luck finding the Apotex generic? I fill my prescription at CVS. Been taking Desyrl/Trazadone for many many years. Preferred the brand one but that's not an option anymore.

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80

I think our bodies adjust to a certain brand of Trazodone. But it will readjust to a new brand, it will only take time. I had to switch from the mfg Apotex to Pliva and had an awful time with my sleep. It took awhile but now the Pliva works for me. I am glad now as Apotex is not reliable in providing the Trazodone on a steady basis.

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83

I was just prescribed 1/2 pill of Trazodonr 50 mg PLIV A

I was told I had to take everyday and must consult dr. To taper off. I would like to use occasion ly.

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88

My Walgreens switched from Pliva to Apotex. I was getting horrible canker sores all over my mouth and couldn't figure out why. Went back to the Pliva & the sores are gone. I'm convinced it was the Apotex. It was a terrible experience, sores all over my mouth & couldn't eat hardly a thing for 4 months. Not sure what's in that stuff, but it was not good for me. Also, the Apotex pills are tiny & I couldn't split them well (I take 1.5).

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91

Hi everyone! My spouse was having that same issue with CVS not able to get Trazodone made by Apotex, but check with your local Rite Aid because they can order it for you & they will transfer your current script! Good luck to you all & hope you can get some good quality sleep!!!

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92

Walgreens will also order it for you; they do it for me, and they have a note in my file that says to only dispense Pliva (Teva).

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97

As an update to my previous post of April 17, 2018, I have now switched back to the Apotex brand of Trazodone 150 mg and my uncomfortable symptoms have stopped. It was tough to find this brand in our pharmacies here, most were using Teva or Pliva (a part of Teva, but with roots in Croatia.) One small local pharmacy still carried the Apotex.

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