Darvon, Distalgesic - The Worst Drugs Ever (Top voted first)

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We - Drs Ulf and Birgitta Jonasson from Sweden - have studied the painkilling substance Propoxyphene - Darvon, Darvocet - since 1994 and we it is the worst drugs ever. No single drug have caused as many deaths.

If you want to know more, please go to my YouTube video:

http:/­/­www.youtube.com/­watch?v=vw5O4tgErsg

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15

I do not understand you: I had a metal plate inserted in my arm after a horrible fracture from a fall from a bicycle, The pain meant I had to leave my job. Now I have distalgesic, I can work again because the pain does not affect me as much. Distalgesic saved my career and allowed me to work and function again. I am grateful for it. Why are you telling me I am wrong?

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16

Distalgesic was a miracle drug, shame it is not available anymore, as the above mentioned bee stings kill more humans than distalgesic a year....

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19

You are a very dangerous person. My husband has been taking distalgesic since 1988 following s cerebral and spinal bend - he was a commercial diver. He was not expected to live, then he was not expected to walk again. It took two years of very hard work to get him on his feet again. However he still suffers from Brown-Sequard Syndrome and HPNS (you look it up as you think you are so clever). The only product which stops the tremors and myoclonic jerks is distalgesic, even coproxamol is not as effective. Now he cannot get any relief, otherdrugs have been tried in the past but nothing worked. How does it feel to leave a patient who was functioning to rot away in bed. YOU MUST BE SO PROUD OF YOURSELF. It is not the drug it is the user/prescriber who is at fault in the case of drug misuse.

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1

I could not hear the whole video because the audio became scrambled. Do you have any other information which you can post back with?

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3

while this is an interesting article it has some lacking in fact which i like to find out. the sampling in Sweden how many were overdose,combined with liquor,other drugs this is an incomplete study. and we think is not scientific we need the details
thank you

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4

To Jr23,

We have all these data in - as you ask for - our 8-9 scientific articles, and you will find them at Pubmed , Search Dextropropoxyphene and Jonasson b.

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5

This is to funny more people have died drunk driving why not take alcohol off the market 1st

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6

LOL Rhoda, why not just take all toxic chemicals off the market and legalize marijuana since it has so many therapeutic benefits and NOT A SINGLE PERSON HAS DIED from it!

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7

I'm a bit confused you mention The average consumption of PROPOXYPHENE in Sweden - during the investigated years 1992-1999 - was 2 400kg/year.
Due to the way this website displays characters there is a space, are you saying the average consumption (per person, based on a total population of 9 million?) was Twenty four hundred kg a year, then saying that there were 200 deaths associated with Propoxyphene?
If the 2,400 kg is correct and 100mg per tablet is assumed, then that would mean 24 million tablets were sold (not consumed.. that can't be proven). Wikipedia says 15.7 percent of the population is kids 15 or under. I'll assume for this post, to generally add 4 percent to include ages 16, 17, 18 , 19, 20.
So the number of children & young adults based on 19% percent of 9 million is 1,710,000, leaving an adult population of 7,290,000.
If an average script is 30 pills, that works out to 800,000 scripts of 30 pills. We'd have to assume about 60% of scripts are refills for the same person, especially in the light of the inference of dependency potential of all opiates.
So (very grossly) 480,000 continuous use patients, & 320,000 one script patients.

If our continuous group refills every month that then works out to 40,000 people. It is unlikely that more than a tiny fraction of the one time scripts would overdose, so the 200 deaths would come from the group of 40,000, which translates into 200 deaths per 40,000 patients or ONE HALF OF ONE PERCENT of the group of continuous users 40,000 x .005= 200.
The dangers of tylenol poisoning are far more well documented & provable than that of Propoxyphene, by numerous sources, and since most propoxyphene compounds contain Paracetamol (tylenol)...
from wikipedia:
The co-proxamol preparations available in the UK contained a sub-therapeutic dose of Paracetamol, 325mg per tablet. Patients were warned not to take more than 8 tablets in one day, a total dose of 2600mg Paracetamol per day. This is in comparison to the 4000mg daily limit on Paracetamol alone, a significantly higher dose.
So apparently the data is inconclusive, since it suggests that taking more than the prescribed daily dose of Paracetomol ALONE can result in liver failure. To blame the Propoxyphene ALONE seems to be a subjective stretch.
To restate, we are dealing with 200 deaths per 40,000 patients who were NOT separated out of your data due to pre-existing conditions such as compromised liver or kidney function, pre-existing heart conditions, or any other conditions as far as I can tell.
In my opinion, as well as the opinion of the majority of US Dr's, Tylenol itself should be considered as a potentially dangerous drug taken in continuous high dosage. Following your logic then, Tylenol itself should be subject to the same withdrawal from the market based on your methodology. I do not dispute that the prescribing threshold is very narrow in this drug before toxicity, however the same can be said for Chlordiazepoxide (librium) for instance, which has a relatively low ceiling before toxicity, but when used as directed, is considered safe. I would welcome your reply to this.

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8

davidh, how can you say not one single person has died from marijuana ? I hate when i hear potheads say that all the time like they know everything. Drug dealers kill eachother all the time, children from families of drug dealing descent have very high suicide rates, and people high on marijuana smash cars and kill themselves and other people, all the time. and you can die from an overdose, you can die from an overdose of water for christs sakes. so dont tell me not a single person has ever died from marijuana, grow up and learn somethin ya crazy high hippie. :-)

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9

Steve, you're talking out your ass.. David H obviously meant no-one has died from the CONSUMPTION of marijuana. Obviously there have been people killed in relation to the black market surrounding its use, but this is entirely due to the fact that it IS illegal. As for dying from an overdose, well theoretically it is possible I suppose, but you quote me just one recorded incident of anyone EVER dying from a marijuana overdose and I'll concede defeat. What's that, you can't? Well grow up and learn something ya retarded boring straighthead. :-)

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10

I agree with the last poster - Steve, you are talking completely OUT OF CONTEXT.

I'm in California and I just really hope that this November's election will finally legalize marijuana. God knows the state can use the tax revenue, plus with pot being safer than alcohol, why the hell not regulate and tax it for those 21 and over ?!? ...

P.S. I'll tell you why ... because the big pharma companies could stand to lose billions if people start growing their own pot and realize that such a natural miracle drug can work better than patented chemicals.

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11

BECAUSE OF A BUS FLATEN MY HEAD AN ABOUT 7 YEARS LATER PROXY HCL 65MG IS THE ONLY DRUG THAT HAS EVER WORKED, AND THE PAIN CLINICS HAVE SAID NO OPTIONS LEFT, THIS HAPPEN IN 89 I AND NOW 68 AND THE PAIN IS UNBEARABLE. I CAN'T GET THE ONLY DRUG THAT WORKS, YOU HAVE KNOW IDEA OF WHAT YOU A TALKING ABOUT I HAVE STUDYED IT MUCH MORE THAN YOU! ALEX

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12

I have studied this. First Coprox package leaflets never suggest adjustment for body mass thus risking overdose for little slim women. Second many problems arise from co-use of alcohol (or abuse). Third it's good for suicide, reason UK stopped. None of these should bar use by appropriate sufferers. Many used drugs are similarly risky but pain tratment needs what suits YOU.

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13

BEE STINGS KILL MORE THAN PROPROX, I HAVE TAKEN 4 TO 6 CAP OF PROPROXPHENE EVERY DAY FOR THE LAST 20 YEARS. AND NEVER ANY PROPLEMS UNTELL THEY TOOK IT OFF THE MARKET. THEREARE NO PAIN PILLS THAT WORK ON ME,NOW I AM TAKING 8 2MG TABS HYDROMORPHONE DAILY AND WORKS SOMEWHAT! I AM AND ALL WAYS HAVE BEEN IMMUINE TO MORPHINE TYPE DRUGS. NOT ALL DRUGS WORK DIFFERENT ON ALL PEOPLE. VALPORIC ACID USE TO KEEP PEOPLE IN PSYCH WARDS. TO MAKE THEM CONFORM,. KILLS LOT MORE BUT EVERYONE JUST LOOKS THE OTHER WAY, ALSO IN NURSING HOMES.DOES LOT OF BRAIN DAMAGE AND MAKES PEOPLE HELPLESS WHICH MAKES THEM EASYER TO TAKE CARE OF.
PROXPHYNE WITH NO ADDITIVES WORK MUCH BETTER. ALEX PALMER 70 YEARS OLD

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14

Millions of people are poisoned to death by any number of medications every year. Sweden is a society obsessed with controlling the citizens in every way possible and you sir, like some many other Swedes, need to quit worrying about what is going on in the UK and US and, frankly, mind your own damn business. You are just another pip squeak Swede who is suffering from "little brother syndrome". Why don't you write a paper about how ignorant and arrogant Swedes actually are and get some help with that, so you don't have to be so damn annoying? And while you are at it, why don't you write a paper about how many people are dying each year in Sweden, "the drunk state", from alcoholism? And you don't even need a prescription for that!

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17

I'm 65 years old and have hemophilia, a lifelong bleeding disorder. When I was a child, drugs to counter hemophilia had not yet been developed. Bleeding into joints, a terribly painful situation, was common. In the late 1950s and early 1960s, Darvon Compound (propoxyphene and aspirin) was the analgesic recommended for such bleeds. The first was ineffective against severe pain, the second is now known to be a blood thinner and so specifically contraindicated for Hemophiliacs. To those responsible for promoting and prescribing Darvon Compound to children with bleeding disorders .... I hope that somewhere along the way they have had the opportunity to truly understand and experience what they did to me and my similarly affected brothers.

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18

As a teenager in the 1950's I had horrendous headaches. Only distelgesic helped, no other drug was effective. It was banned because of abuse - mainly alcohol.

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20

I have been a suffer from RLS form the age of about 18 a generic disorder my father, his brother who sadly hung himself back in the 60's with pains in his legs, my brother suffers in aus and my youngest son is now 34. For years I was prescribed co proxomol and it worked wonders, I think I was on 1 or 2 a day then professionals like yourselves decided too many were abusing it. My G P didn't even have the curtesy to talk to me. I just arrived at the pharmacy to find Panadol as a replacement after many arguments at my surgery ending in threatening that they may find me, a normal well balanced women hanging from a tree. They then sent me to a neurologist who prescribed zopiclone, a Parkinsons drug. It helped I believed some but not me. But now in the UK they have decided that those who are not Parkinson suffers cannot be prescribed too expensive! Withdrawals weren't pleasant but I can cope with stomach cramps, sweats, etc. But my legs and arms are back with a vengeance. Did any of you professionals ever wonder how many suffers are now buying on an illegal market, couldn't there have been some way to separate those at risk and level headed folk in pain. I don't know what to do now. The addiction system in the UK sucks. They seem to have given up and just supply the unfortunate folk with Methadone that seems even harder to get off of than other opioids. And the powers that be know full well they sell the dam stuff. Help please.

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21

My son died after taking this drug "recreationally" He was 19 It was his responsibility that he took a drug that was not prescribed but I fear his death was partially due to the compounds in this particular drug He was a great young man who made a fatal mistake one night in Oct 1999

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