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Terrified to start Trintellix!

Hi....I was given a 2 week sample of Trintellix to add to my Paxil 60mg. I'm one to do all the research that's possible & also one to read all the reviews available before starting a new medication when it comes to my mental health. I'm very hesitant after reading so many negative reviews with people complaining of severe nausea and stomach pain. I'm absolutely cannot handle vomiting.... I'd rather take a beating than to vomit. However, can I get some advice about this situation? Is it really worth the awful side effects? Should I also ask my doctor to prescribe me some antibiotics nausea medication to take along with the Trintellix? I certainly could use some advice on this. Thanks! ## There are quite a few typos in my original message I see. I did not mean to p...

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brintellix side effects severe

DESPERATELY NEED HELP ABOUT BRINTELLIX!!! I have been on 5mg Brintellix for last 10 weeks. About 9 days About 9 days ago I started to feel like i was coming down with flu. week progressed and flu like symptoms got worse every day: flushing, feeling like i had high fever but without actual fever, agitation, muscle cramps, bad nausea, diahrrea all day long, fast heart beat, headache, etc. after several days of symptoms getting worse, on Sunday last I had the feeling i was going to DIE!!! worst flu like symptoms and severe anxiety, depression and suicidal thoughts. I skipped the sunday dose and then cut the monday dose down to 2.5mg. it is wednesday, and most of bad symptoms have gone to mild or moderate. Dr thinks i had case of serotonin syndrome n this med. But, no one can explain why si...

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Brintellix/Trintellix Long term side effects

I have struggled with depression for most of my life, and am always in search of the perfect antidepressant. I work with a psych doctor who is always willing to try new things. 10 months ago I started 5 mg of Brintellix daily, within a week my mood was significantly elevated, I was sleeping better, waking up much earlier and was more motivated to do things in the morning. I went up to 10mg daily However the nausea was dreadful! I pushed through for a couple of weeks, changed to taking the brintellix at night and after a while it subsided. My mood got better and better, I had recently turned 50, and had gained a little weight, so with my new found morning energy I started working out 2times a week with a trainer, and then walking most other mornings! The walking then changed gradually to...

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ADHD and cognitive problems

I was prescribed this medication to take with my vyvanse for my add and cognitive problems that I have been dealing with most of my life. As of two years ago, at age of 28, I started to get lost while driving and I also started to get bad memory blocks that would last about 10 or so seconds. I forgot how to turn on the car as well as forgot how to use the microwave. My speech gets mumbled up and I always seem to forget what I'm saying in midst of sentences. I started vyvanse and lexapro, and other first class ssri's and none of them worked. The vyvanse does help but only to a certain extent. It makes me very relaxed and ridiculously tired, so the vyvanse does help to calm me down but it does not help my memory at all! I told my Psychiatrist all this and he put me on 5 mg Brintel...

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Brintellix (Trintellix) withdrawal

Started 10 mg Trintellix 3 weeks ago. Vomiting at least 2x a day and constant nausea, fatigue, muscle and back pain. Trying to wean off it - doctor said take it every second day for a week then go see her. What is the normal time frame for withdrawal? I am terrified of this drug. I am diabetic and it is making my sugars wildly fluctuate too. ## Called Lundbeck (canadian office in Montreal) today to get advice on how to wean off/stop taking Trintellix. Shocked to be told "there is NO protocol for weaning/stopping this drug. You have to let your doctor decide how to proceed"! "Everyone has a different reaction". My doctor is away for a week so. My pharmacist and I are trying to figure something out, but I am absolutely stunned at Lundbeck's answer ## Hi Judy, Sorry to ...

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Trintellix Review

Why did I read that you should not take this medicine till 2020? I was just given a lot of samples of 5mg that my doctor wants me to start for my depression. I am scared to death to start because of the horrible reviews & side effects that sound horrible. I have never heard of this drug. Can you please help me with this. Also if I do decide to start when is the very best time to take it? ## Has anyone else gone down from 10 to 5 mg of trintellix? I am afraid I will have some anxiety doing this. Can anyone give me advice? ## I've been on Brintellix/ Trintellix for going on 2 years. Saved my life. I am on a low dose, with buspar piggy back, but no longer a handful of drugs. If you've failed the rest, give it a shot. Start low. I am great on just 10mg, and I was suffering from ...

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Brintellix missed doses and side effects

Hello, I just wanted to put this out there; I missed 2 days of my Brintellix, as I had to wait for the pharmacy to order it, and I have been crying constantly for 2 days now. I got it today, but just wondering if anyone thinks I'm being ridiculous or is it possible? ## Hello, Lili! How are you? You aren't crazy, that is entirely possible. Please don't beat yourself up over it. In the future, you may want to talk to them about keeping it in stock for you, or requesting your refill a few days ahead of time, so they can order it in by the time you need it. The FDA lists the typical side effects of this medication as possibly including nausea, dizziness, dry mouth, weight changes and vision changes. Is there anything else I can help with? ## I stopped 3 days of my brintellix 20 ...

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When do the side effects of Trintellix/Brintellix go away?

I recently was prescribed Trintellix by my psychiatrist for anxiety and depression. I told her I cannot be on a medication that will cause weight gain and or fluid retention. Since starting this medication I've been on it for two days I feel really weird, lazy and like I just don't want to do anything. Low mood. I honestly have zero appetite, and my cognitive thinking is very slow. I honestly feel like I am on a super low dose of Vyvanse. She also gave me samples of Viibryd but I heard that medication is notorious for weight gain on here and I am scared to take it. Did anyone else have these side effects when starting this medication? Did they go away? Also, if this isn't the medication for me, does anyone else know what others are good that will not cause horrible weight ga...

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Scared to start Trintellix

I'm scared to start Trintellix. I have Major Depression. I get scared to start any new medicines but especially depression meds. My Dr gave me samples. I was also waiting to see if my insurance would cover it. (New insurance Oct. 1st) They said no unless I can produce dates and why others wouldn't work. That's impossible. I take Vyvanse and Klonopin. I've taken myself off depression medicines if they make me feel bad or weird. I can't take any that will make me gain weight. That just adds to the depression. After back surgery I only have 10 more lbs to lose. I can't do anything that I used to do because of back problems, so inactivity and not doing the things I love has made my depression worse. Other issues as well. I feel empty, things that used to make me shin...

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Have been taking brintellix for 3 months

Hello, I have been going to physiatrist and getting brintellix for about 3 months. Before taking any meds I constantly having suicidal thoughts very frequently. Then I start to go to physiatrist and taking brintellix 5mg for about 2 months, I was getting better until they change brintellix dose to 10mg. Now I’m back to where I was before taking any meds, getting worse and worse. Do anyone know how to help and why? ## I found the same when I went from 5mg to 10mg it kinda made intrusive thoughts amplify I have found after about 8 weeks that 5mg is best taken at night that way I dont get the nausea and just feel relaxed even 2.5mg would be ok for me I think.. ## The NIH does warn that these issues can be a side effect of this medication, and it is normal for them to worsen, when you...

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TRINTILLEX/BRINTILLEX SEVERE RASH AND ITCHING

I was on Trintillex for about 3 weeks and developed a rash all over my body. I didn't know where it was from originally so I did not stop taking it. After about 21 days I decided to stop taking it because my doctor said it could be a potential side effect. My rash is so severe and I have been off of the medication for about a week now but the rash won't subside. Does anyone have an idea of when it will go away? I know the half life is 66 hours so I am nervous it's going to be in my system for a long time and the side effects won't go away. I was taking 5 mg. If anyone has any ideas of when it will go away or how to help it/ make it go out of my system faster PLEASE let me know. Thanks ## Julia! I am so sorry about the problem you've experienced. How are you doing, no...

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Stopped Brintellix

I was on 10 mg of Brintellix for about 4 months and then my doctor added 10 mg of Rexulti. I felt like i was being stimulated. He then upped my Brintellix to 20 mg and my anxiety went crazy. I was having racing thoughts and couldn't sit still. In my mind i had to be doing something all the time. I also started having panic attacks. This was only over a 2 week period. I then dropped back to 10 mg and cut my rexulti to 5 mg. I told the doctor I wanted to switch back to celexa. He told me to just stop the Brintellix and start the celexa at 10 mg. It's been about 2 weeks now and I still have panic attacks and I wake every morning feeling anxious which last most of the day until the evening. I can't handle this anxiety. I feel amped up. It's like the side effects are continui...

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best time of day to take brintellix

I can't seem to figure out what is the best time to take my trintellix... am or pm. I've been on trintellix for a little over a month and don't sleep very well and stay very tired during the day but I had these problems before I began trintellix so how am I supposed to figure out the best time of day to take it??? I've been taking it at night but switched to taking it in the morning today amd can't tell any change. I just want to take it at the time of day it will help me the most.... Thanks! ## There is really no specific time that is best, it depends on what works for you, the main issue is to just be consistent in taking it regularly. The FDA warns that it may cause side effects, such as nausea, dizziness, headache, mood changes, and weight changes. How long have ...

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Switching from Zoloft to Brintellix

Today my doc told me to reduce my Zoloft from 100 MG to 50 MG for the next 6 days. On the 7th day I will begin 10 MG of Brintellix in the morning with breakfast. If I experience any sleepiness I should start taking it in the evening. My follow up visit is scheduled for June 29. I have tried many amtidepressants over the years with minimal to moderate success. I hope this is magic bullet. ## don't do it! i have been on ssri meds for over 20 yrs. dr started me on trintellix 3 wks ago. have not been out of the house since then due to nausea, vomiting, diarrhea, fatigue and more. Now trying to wean off of it but dr and pharmacist are not sure how to proceed with this. i am also imsulin dependent diabetic andy sugars are erratic. terrifying drug at least for me. ## Day 6. I have complete...

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Increasing brintellix/trintellix to 20mg

Hi everyone, Please can someone help me? 4 weeks ago I increased dosage of brintellix to 20mg (bc I started feeling very low again) after taking 10mg since December and finding improvement. After 4 weeks of still feeling low, I have suddenly started feeling nausea and general sickness. Is this normal after 4 weeks of increased dose? Thanks in advance. The gp I spoke to about increasing had not even heard of the med before so I doubt she would have been able to advise on side effects of increasing unfortunately.. here in uk it's still a relatively new drug. ## Yes, if you increase your dosage, it is normal to experience more side effects for awhile, they usually taper off, after about 4 to 5 weeks, according to NIH reports. You may also experience anxiety, and weight changes. Are you...

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Weight gain after stopping Trintellix

I started Trintellix in December 2015. I did have nausea in the beginning but only short term. It worked pretty well for me-took it mainly for anxiety. I noticed I lost a couple pounds when I first started it but it seemed to normalize for the most part. At the first of this year I found out my insurance won't pay for it and the monthly cost is too much. I tapered off over about 10 days-was only on 5 mg. I have experienced multiple side effects, more than I bargained for-runny nose, fatigue, shortness of breath, feeling cold, bursts of irritability, decreased alcohol tolerance, and most disturbing: weight gain. I'm a small person-5,3", usually 112 pounds. But I am gaining 0.5-1 pound/week. Has anyone else experienced weight gain after stopping? The other side effects seem to...

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Brintellix nearly killed me (serotonin syndrome)

I recently had an emergency reaction to Brintellix. The active ingredient is Vortioxetine and it has 532 known drugs that if taken at the same time will cause serotonin syndrome. In my case i had withdrawals changing from one med to another, so i was give an anti-nausea tablet. It turned out this was one of the meds that clashes with Vortioxetine. It is now clear to me that little is known in the Dr community regarding this drug. ## Hi Simon, Sorry to hear about your severe reaction to Brintellix. I agree with you wholeheartedly that our doctors should be taught much more about these types of medications & interactions in school. Unfortunately, this level of education is handed down to pharmacists instead of the physician who prescribes us something for a very specific reason. So wi...

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brintellix false drug screen positives

Hello, I am hoping to get some responses on this, I have been going to a pain management clinic for the past 9 months to help with deal with some pain from having discs removed and my neck and back and replaced with metal plates. I go there was a month and get urine drug test they used to somehow determine that I am taking medication as I am suppose to. Till this month I have not had any issues, but on my last screening this week they claim that my urine showed for a trace of morphine. The levels for the pain medication I am prescribed show normal, so I got a big lecture about external drug usage and was told i was but thrown from the program is it happened again. The only thing different I can think of was I was prescribed Brintellix a month ago. All other medications I have been on ha...

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Trintellix and can't sleep

I have been taking 10mg of Trintellix in the mornings for just under 3 weeks and it works well for me, but I can't sleep well and the lack of sleep alone is making me consider stopping this medication. Would it be better to take it at night? Is the sleep issue something that normally goes away? ## If the Trintellix is making you drowsy, it may be a good idea to try taking it at night, like you mentioned. Another issue is, were you already having difficulty sleeping before you started taking the Trintellix? If you were, it may not be the Trintellix. If you weren't, it probably is. You can also maybe lower it to 5 mgs for maybe 3 weeks, then jack it back up to 10 mgs if you feel you have to. That may help your body adjust to it. Good luck. ## Most medications in this class can cau...

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brintellix and zoloft

Hi. I'm about to switch over to Brintellix from Zoloft. The Zoloft has been good for my depression, but my libido is pretty much non-existent. Do I need to wean completely off the Zoloft before I start the Brintellix? I'm getting mixed messages about this. Anyone have personal experience in taking both while weaning from Zoloft? ## Hello, Dar! How are you? Yes, one should be stopped, before starting the other, unless your doctor has instructed you to do otherwise. Brintellix is a little different than Zoloft, the FDA classifies it as an atypical antidepressant, it's a serotonin modulator and stimulator. Typical side effects are listed as possibly including nausea, dizziness, constipation, dry mouth and unusual dreams. You should also be made aware that it can cause problems ...

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