Taking Subutex And Percocet Together (Page 10)
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My doctor just put me on subutex along with percocet. I've been on percocet for yrs for severe and chronic migraines. He told me to take the subutex and if it doesn't work to take a percocet. I usually take 15 mg percocet at a time. I've read some stuff online that worries me. Some people say if you take percs with subutex you'll go into withdrawals. I went through severe withdrawals with fioricet months ago and I don't want to go through that hell again. I took my first subutex about an hour ago and I still have a migraine so I want to take a perc now. Can I do that or will I get sick?

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444

JOHNNY: Yet again, we have another authority on here dispensing bad advice. I just got through sitting up with someone who with into STRAIGHT UP, HARDCORE PRECIPITATED WITHDRAWALS. Guess what, genius? They took SUBUTEX too soon after full-agonist opioids, NOT SUBOXONE. The Naloxone? Makes NO difference. It is ONLY in Suboxone to keep people from taking it intravenously. This person was SIX DAYS off of methadone and STILL went into a really bad rattle. From SUBUTEX. Geez, I wish you *****s who know NOTHING about the drugs you take would stay the heck off of here.

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443

PharmDray: You are flat out WRONG. Yes, bupe is a partial opioid agonist. It is also a partial opioid ANTAGONIST. That would be the "blocker" part. And to the other person who said "there's no naloxone in the subutex, so you are good"? Johnny? Yeah, NOPE. The BUPE ITSELF is a partial opioid antagonist. The only reason that Naloxone is in there is to keep addicts from taking it intravenously. Naloxone has a VERY low bioavailability when taken sublingually, therefore you really don't get any effect from taking it under your tongue. Intravenous use is a different story. I have been an opioid addict for 30+ years, have been on Subutex, Suboxone AND methadone, and am involved in medical research. So no, I didn't get my info "from my buddies". I got it from two different M.D's who are addiction specialists (one of whom was the addiction specialist for the Denver Nuggets NBA team) and I got it from my own research. The amount of misinformation on here is STAGGERING. All being presented as if it is from some "world's foremost authority". I only post facts on here; you don't want to believe me? Go ahead and take some Subutex after taking some full agonist opioids. Let me know how that works out for you. I don't give a crap if you ARE a pharmacist (there are plenty of pharmacists, including yourself, who are just plain wrong) but nope, sorry, the naloxone is ONLY in there to keep people from taking it intravenously. Heck, you can look on friggin WIKI and find that out. BUPRENORPHINE ITSELF IS A MIXED PARTIAL AGONIST, PARTIAL ANTAGONIST (BLOCKER) OPIOID RECEPTOR MODULATOR. Meaning, GENIUS, that the ANTAGONIST part is the "blocker" for lack of a more scientific term. Got it, pal? That clear to you? And if you are indeed a pharmacist, maybe you should do a bit more research. Or make a career change. You aren't doing anyone any good dispensing misinformation. And BTW, I know for a fact that you can NOT come up positive for ANY kind of opioids and be involved in the dispensing of pharmaceuticals. So you are full of it anyway. Good job, liar. Good job.

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442

You went through fioricet withdrawal? And it was ruff?....Damn how long were u on it?...Your talking about the pills with a slight barbituate in it and slight caffeine in it right? Usually comes in the pills with the imprint of the persons face/head with like a pounding headache look to it?...Wow....My x use to give those to me they never did a thing..Very weak..They dont make those ruff strong barbituates anymore that were screwing people up like tumanol and seconal....My brother in law who was a lot older then me told me about those things lol..He was an opiate addict at a time so he knew about drugs..He said the were pretty hardcore but they took them off the market years ago..Just like they took qualudes of the market years ago. In the 70's they were called the love drug...And they were prescribed but they became too popular for their own good and they pulled those off the market..They werent a barbituate but kinda in their own class..Only place they have them now is in south africa..Where back door chemists make queludes themselves lol.....Ohh but dont worry too much about the subutex ...Im on it....Too..Just dont ever ever mix it with methadone or u will have the worst withdrawal known..And naloxone in suboxone really has nothing to do with blocking lol..Its just a lil additive I believe recckitt benkster the pharm company added to regular buprenorphine which is subutex and has been patented in the 50's and used in the mid to late 80's I.M. As in the muscle by needle for opiate addicts because buprenorphine in itself is the real opioid/opiate blocker...Naloxone was added to the other companies as a cash cow full of lies..Lol..Buprenorphone/subutex itself is the blocker and will make u sick if u mess around the wrong way big time just like suboxone....And bupe aka subutex fills the 3 main mu opioid receptors and with about a few days or a week hit the "Ceiling effect" meaning any opiate u take will bounce off no matter how much...Including if u take 1 or 10 subutex u wont feel a thing..Might od or feel sick but thats it...Difference is suboxone is a garbage cash cow and u are not suppose to take naloxone every day it is like toxic on the body..First they found that it ****s the kidneys up..The suboxone from the naloxone..Now they say it ****s the liver up, and why do u think they take a woman off of suboxone and put her on regular buprenorphine aka subutex when prego or nursing.. Cuz its bad for the fetus, the baby...The naloxone in the suboxone...Cash cow doctor kick backs reckit benkster or whoever makes suboxone are in with the dea and feds lying and even giving them kick backs I think in some areas from what I have seen...Cuz most sub doctors do not want to write u subutex....Only suboxone...Lol..And ones excuse was cuz u can abuse subutex and it's diverted on the street...Lol..Yea and how many of us know *****s that abuse suboxone strips..For nothing..And sell them on the street....So...Uh yea there goes that theory suboxone makers...It depends on if the person is ready or not..They can abuse subutex or sell it; or suboxone...I myself have left over pills..Always and don't abuse it ...Heh..That is retarded....A waste...Heh....I'm just surprised u went though withdrawal from those weak things...

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441

The only way you go into withdrawal is if you take a Suboxone then take a pain pill. Subutex has no naloxone so you're good.

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440

So if your on sebutex and you get prescribed pain meds like tylenol 4 Will you even feel the tylenol 4s or not

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439

Your wrong I'm sad to say. Buprenorphine is NOT a "blocker" of any kind. It is in fact a partial opioid agonist. That means it sits very well on the mu receptors so much so that if any other pain meds come along they just float by because your body is sated with the buprenorphine. The full agonist opioid pain meds can attach to other receptors but the only receptor that makes you feel euphoric is the mu receptor, that's why people say pain pills don't work when on subutex. Now as for he "blocker" the only opioid antagonist is naloxone/narcan if given intravenously it will strip whatever opioid whether it be a full acting or partial acting opioid out of the receptor hence the precipitated withdrawal. So in conclusion you cannot say that buprenorphine is an opioid blocker. That is an untrue statement. I am a pharmD and I myself have been on subutex for years for chronic pain from a car accident and I had to have surgery while on subutex.

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438

I'm just curious how you got all your information. You claim to know everything about these drugs, are you a drug rep for suboxone? Are you a pharmacist, or pharmD? Or are you just commenting on things you've heard your buddy's say

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437

Subutex is buorenorphine which is a partial-agonist opioid. It is NOT an opioid blocker. You are the one giving false information. Opioid blockers are in suboxone which is buprenorphine and naloxone. Naloxone is a reversal/blocker at the mu opioid receptors. They actually give buprenorphine in the U.K. As an analgesic (thebaine) it works very well. Everyone is different and everyone's body is different. But to just flat out state that subutex is an opioid blocker is false information.

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436

Exactly. Someone i know takes oxy then will take subutex right after. Or mix em together on occasion. No precipitated withdrawals. That's caused from naloxone which is in subxone not subutex. Don't post misguided or uninformed health information on the internet. You could kill somebody because your "opinion" is wrong.. not directed at anyone specific but damn know your s*** or keep it to yourself. Me and this person seem to be the only ones with true knowledge in the field.

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435

RJ: Both things you took are in pretty small amounts, so you may be ok. Or you may not....what DID happen? You tell us? In the future, it is not recommended that a person take Bupe that close to a full-agonist opioid. This can throw you into Precipitated withdrawals, which are basically the 3rd circle of Hell. Not sure why you would WANT to take Bupe so close to an opioid, but that's your business I suppose. But it's not only counterproductive, its just plain not very smart. Look at it this way; you are taking an opioid, and then following up the opioid with an opioid BLOCKER....what is the logic in that?

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434

Taken Percocet 10 3 hrs later took burprophen 8 mg what will happen .

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433

GARY: It doesn't matter how many times you tell this to some people, they will INSIST that you can take full-agonist opioids, and then take Subutex and be perfectly fine. Already been there with these people, MANY times over. This woman on here, "Anna"? Wrote a whole PARAGRAPH of bad information, stating it as if it were the gospel. It's one thing to not know what you are putting into your OWN body, but to come on a forum like this and dispense just plain WRONG information to others when you don't have a clue is ridiculous.

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432

CRYSTAL: Valium is neither a painkiller, nor is it a muscle relaxer. Valium is a Benzodiazepine, which is a tranquilizer/anti-anxiety medication. It would NOT be prescribed for pain or muscle spasms.

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431

Your info is completely WRONG; Buprenorphine is a semisynthetic opioid derivative of thebaine. It is a mixed partial agonist opioid receptor modulator ...it is Suboxone. It will knock Percocet off the receptors and put you into precipitated withdrawal's if you take the Percocet's first and then take that but if you take that first and follow it up like an hour later with Percocet that will not happen and as far as your claim about Oxymorphone it is not new it's called Opana and has been around for a very long time.

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430

SLANT: Don't bother. Everything you just wrote? I have told them all this until I can't take it anymore. There are some on here that are just NOT going to believe you. When I hear someone say, yet again, that "as long as there is no Naloxone in it, you are fine", I just want to scream. Some of these people are just going to have to find out for themselves. And no, you DON'T want to find this out. I have personally been through it, and I was seriously contemplating jumping off of the roof. I thought I had been through bad withdrawals.....NOPE. Those Precips? Are no friggin JOKE!.

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429

If you are already taking sub then there should be NO reason what so ever unless you're trying to feel high that you would need another pain killer. I would ask your doctor for valium for any neck pain to help relax the muscles. I have three children that I gave birth to naturally without any pain killers or anything. Your body is not used to feeling any pain since your on that medication so giving birth since yes it is painful is going to seem worse than it really is because you've been numbing yourself. 12 years ago I was addicted to opiates and was put on suboxone so I can relate to NOT feeling any pain so that even the littlest word feels horrible. Again I suggest speaking with your doctor about going on something like valium and also since your pregnant your child is now already addicted to the subutex. I know that's the standard for pregnant women however it has changed the last few years because of the sad withdrawals the babies are going through. Please please please speak with your doctor. In fact I would even maybe start seeking out advice from another doctor.

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428

Wrong. The bupenorphine in either has THE strongest affinity for all three receptors. The naloxone is to prevent mainlining mostly. Yes naloxone/narcan IS what they give OD patients to bring them back. Trust me. If you take subutex after ANY narcotic analgesic you WILL never do it again. I promise.

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427

Yes, Subs are made to get you off of full-agonist opioids like Percs, Roxys, etc. Not made to be MIXED with those things.

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426

TASHA: May I ask what dosage of both that you are on? And this really isn't an "everybody's different" situation. This is what the drug is SUPPOSED to do.

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425

They dont make me sick. Subs get u off roxys or oxycodone. If mix sub a blocker wont allow u to feel the oxycodone. Hope that helps... Tasha.... I do both all rime. But everyone diff and effects everyone body diff

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