Active Ingredient(s): Collagenase Clostridium Histolyticum
FDA Approved: * February 2, 2010
Pharm Company: * AUXILIUM PHARMS
Category: Skin Care

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Xiaflex Overview

Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a virulence factor, facilitating the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.[1] Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secret...

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Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Collagenase

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Possible Dosages for this and Related Drugs:

Collagenase Clostridium Histolyticum
  • Injection
  • Ointment: 250IU/g, 250u/gram, 250unit/g
  • Solution: 0.92mg/vial, 0.9mg, 1.84mg/vial
  • Vial: 250u/gram
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Xiaflex: (1 result)

Sorted by National Drug Code
  • 66887-003 Xiaflex Kit by Auxilium Pharmaceuticals, Inc.

Other drugs which contain Collagenase Clostridium Histolyticum or a similar ingredient: (3 results)