Weight Gain After Stopping Trintellix (Top voted first)

Updated

I started Trintellix in December 2015. I did have nausea in the beginning but only short term. It worked pretty well for me-took it mainly for anxiety. I noticed I lost a couple pounds when I first started it but it seemed to normalize for the most part. At the first of this year I found out my insurance won't pay for it and the monthly cost is too much. I tapered off over about 10 days-was only on 5 mg. I have experienced multiple side effects, more than I bargained for-runny nose, fatigue, shortness of breath, feeling cold, bursts of irritability, decreased alcohol tolerance, and most disturbing: weight gain. I'm a small person-5,3", usually 112 pounds. But I am gaining 0.5-1 pound/week. Has anyone else experienced weight gain after stopping? The other side effects seem to be waning but not the weight gain.

4 Replies

Earliest Newest Votes
1

It is normal to experience discontinuation symptoms, which the FDA lists as possibly including headache, mood swings, anxiety, and sudden outbursts of anger.

Weight gain is not a normal withdrawal effect, but it could be due to the other symptoms causing you to eat more than usual and not be as active, since you aren't feeling that great.

Have you considered asking your doctor if you can try an alternative medication that your insurance might cover?

Was this helpful? 0
2

Thank you. I am considering doing that. I hoped I would do well off medication but it seems I may not be ready for that.

Was this helpful? 0
3

Yes, I continue to gain weight every SINGLE day. I stopped the Trintellix over a couple of weeks ago, when I noticed that the medication though initially, was like the panacea of depressive symptoms, but all my symptoms came back AND the weight gain continues. I am very unhappy about that. I wonder when the weight gain will stop. my diet is about exactly the same...I feel like it may be brain chemistry was altered for the two months I took the Trintellix ?

Was this helpful? 0
4

Re: Down on this med (# 3) Expand Referenced Message

I also had to stop the trintellex. I started on 5 then 10mg and ultimately ended up on 20mg. I am small framed at a whopping 5’2” and my normal body weight is between 120-125 ( I’m heavy chested). After the year mark on the trintellex it was doing nothing for my depression in fact I actually felt more depressed, but my anger was in check so I was stuck in what to do. Then literally “out of nowhere “ I gained 20lbs in two weeks. No change in diet or activity level and the bloating, omg I look six months pregnant. I’ve been off of it for almost a month an Cd still haven’t lost the weight or the bloating. I don’t want to go anywhere and I’m so uncomfortable. Has anyone else had this experience?? I’m scared that I’ll never get my flat stomach back.

Was this helpful? 0

More Discussions:

Regain weight after stopping Belviq

After you reach weight goal and come off the Belviq, any reports about re-gaining all your weight? ## Hello, Florida! Ho...

1 REPLY
Weight gain and depression after stopping Chlorthalidone

I have successfully lost 100lbs over the last 2 years. I went off chlorthalidone three weeks ago and I have gained about...

4 REPLIES
Massive weight gain after stopping oxybutynin

My 8yo daughter was on oxybutynin for 3 years for bladder issues. After doctors deciding she didn't need to be on it...

2 REPLIES
Weight gain with trintellix and klonopin

I need to know if I will gain weight while taking the medicines, Trintellix & Klonopin, together? ## There is a chan...

3 REPLIES
Weight gain on Seroquel or Trintellix

Which is more apt to cause weight gain, Seroquel (400mg) or Trintellix (10mg)? ## Hi Heather, Because everyone's bod...

1 REPLY
Weight loss after stopping Mirapex

I have gradually gained weight since starting .25 mg of Mirapex about 4 years ago. I have rapidly gained weight since my...

4 REPLIES
Stopping Purbac caused weight gain

Hi I have been taking Purbac, Aluvia, Tremoc and Activio vitamin for 3 years. My new doctor stop prescribing it upon see...

1 REPLY
Weight Gain after starting Xarelto

I just started (09/29/2016) Xarelto - 15 mg 2x/day for a large DVT and multiple PE's. In one month I have ballooned ...

32 REPLIES
Weight gain after taking citalopram /other anti-anxiety meds

I have been taking citalopram for a few years. It was fairly effective but switched to Paxil for a few months and then s...

1 REPLY
Weight gain after consuming regesterone

Hi doctor, I was taking regesterone medicine throughout May month due to spotting issue + hormonal imabalance..after the...