Watson Vs. Mylan Generic Lorazepam Side Effects.

Kitty Says:

Been on Sandoz mfr. lorazepam for 10 years; no problems; no need to increase dose. Sandoz stopped mfr. Now, can only get these generic's & Actavis. Having lots of troubles getting results; either nothing or zonked. Anyone else w/any experience which mfr. is closer to Sandoz (since FDA approves up to 2% differences in generics). Thank you.

531 Replies (27 Pages)

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Penny Says:

Hello! I have been getting 90 days supplies of Lorazepam 1MG from SANDOZ....my new Rx just came and it's from ACTAVIS.....it does not work or relieve any anxiety at all....I might as well take a placebo...it does not work at all....I took 2 pills...nothing and then 1hour later took 2 more....before with the other brand...I would probably be asleep....but,nothing with this new brand.....I do not know what to do about this.......

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Erkle 57 Says:

I have been getting 90 day supplies of Lorazepam 2MG from SANDOZ my new Rx is from ACTAVIS. It does not get rid of nervousness, panic attacks or help with my dysautonomia and I feel like I have electricity running through my body. My pharmacist said it was the binding ingredients and we would try a new generic next month. I hope I can keep it together that long. This generic is causing me more trouble and I feel like I am back where I started. Sorry for you other guys because I know how it feels.

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Verwon Says:

It is unlikely that the problem is solely related to the binders/fillers in the tablets.

The real problem with some generic medications stems from the fact that to be able to be sold on the market, they only have to be within plus or minus 20% of the amount of the active ingredient in the name brand. The FDA considers this an acceptable therapeutic window.

Where the problem arises is usually due to the fact that they only have to measure themselves against the name brand and be within that plus or minus 20% of it, they do not have to measure against each other.

This means that there can be dosage fluctuations between generics from different manufacturers.

Some manufacturers of Lorazepam that haven't been mentioned, that you may want to see if your pharmacy can order for you to try are: Biovail Corporation, Excellium Pharmaceutical, Mutual Pharmaceutical, Ranbaxy Pharmaceuticals and Teva Pharmaceuticals.


Is there anything else I can help with?

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Chuck Says:

same problem have been taking Ativan for 25 years for anxiety health insurance changed and now I get a 90 day supply from Actavis they do not relieve anxiety

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Linda Says:

I have been using Watson generic Lorazepam for years and occasionally the pharmacy has given me other generics. The problem is that the other generics are not as effective as the Watson. Why is that?

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Mary Says:

I have been on 1mg of Lorazapam for 5 yrs. manufactuerd by Sandoz when I got my new pills they were from Activas. Terrrible replacement.
Did nothing for anxiety only made me a little sleepy. It also gave me a terrible edgy feeling. I had to resort to buying the brand which is fine but costing a fortune. Does anyone know of a good replacement for the Sandoz Lorazapam

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Loraz Says:

Yes just last moth i was switched from "Watson" Lorazepam to the bed "Actavis" brand....NO effect at all, other than to put me to sleep.... I don't recomend it at all

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Mary Says:

Has anyone had any experience with the Randbaxy generic for Lorazepam.

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Loraz Watson Says:

242/2 round are great, dependable. Very little fillers & good active %

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Mary Says:

I tried the Ranbaxy brand did not work for me. I have had to go back to the brand. Has any one found a good replacement for the generic made by Sandoz the brand costs a fortune. I have been in contact with Actavis with their horrible product. The brand is good but gives you heartburn. Sandoz had the perfect generic. I also found out after talking to my doctor that since I was on their product fo 4 years and was switched to a new product Actavis which is not the same I am having withdrawal symptoms even though I was taking it but the brand works once you get started on it but not right away.

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frazzledzombie Says:

After having taken 1mg of Watson (I think) lorazepam PRN for years and years (and real Ativan, on a few lucky occasions), I ended up with a prescription from Actavis. The Watsons knocked out my anxiety/rage literally within five or six minutes and never gave me the slightest trace a side effect, even if I took two or three in a day. These Actavis pills are darn near useless and make me so tired! They're so tiny that at first, I thought that they were 0.5s; no wonder they don't work; there's probably hardly any actual lorazepam in them. Then again, I've had actual 0.5s that worked better.

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Mary Says:

Those Activis pills are awful. I have complained about them to the company. I tried Ranbaxy did not work. I am now on the brand works better but still not as good as the Sandoz. I am thinking of trying the Watson. I am so sorry you are having trouble. I know how awful it is.

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Mary Says:

I have written to the company and it is very easy to do. I f you are having problems with the drug you can email them or call them. They called me back and said by law they have to do an investigation. I am still working with them on this. I am not dropping. Everyone who has problems needs to contact them. I truly believe if you had a drug test with their stupid pill they would probably find no benzos in your system. It is not a pill. Of course you know I am talking about Activis!!!!!!

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AC Says:

I've been on Purepac/Actavis 0.5 lorazepam prn for sleep for about 8 years. My pharmacy just switched to Ranbaxy which I hate. I wake up groggy and sluggish. I found a pharmacy which still carries Actavis in my area and am going back to it.

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Mary Says:

Actavis worked for you not for me. I could not get any results from it. I was taking Sandoz now I am getting the brand.

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AC Says:

I'm happy for you.

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JodiJ Says:

I have been on the Watson brand for years from a local pharmacy. Last month I just switched my lorazepam prescription to Walgreens. I was skeptical because the pills looked different but figured it was no big deal; well they were Actavis. They do NOTHING but make me very, very tired. I called Walgreens and they had me call my local pharmacy that I used to be at to obtain the mfr. So Walgreens is going to check if they can order Watson, if not I will have to transfer back to my local pharmacy. I cannot believe the differences 2 of the "same" drugs can have!!!

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Penny Says:

I had my Doctor switch my RX to Xanax 0.5 mg,get the generic form Alprazolam. I only have to take 1/2 tablet. It has worked excellent for relieving my anxiety.
You may want to ask your Doctor's about changing.

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The Experienced Observer Says:

Service at Target pharmacy was so bad I finally walked out, had been getting 2 mg lorazepam from Watson, 242/2, very good, no problems.

Walgreens carries Purepac (Actavis) and it seems like real garbage.

Gotta do something about this. Stuff costs money.

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The Experienced Observer Says:

Yeah, Watson is good, Excellium and Mylan not bad, but Purepac just makes you feel like there is something wrong with you. That's not quite the idea...

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Most Recent Replies:

Sunset Says:

Re: Nora Taylor (# 36) Expand Referenced Message

Watson has been discontinued. That's my problem.

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Sunset Says:

Re: LP (# 31) Expand Referenced Message

I agree Watson was the best and now you cannot get it. Teva substitution doesn't work ):

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Sunset Says:

Re: kathie (# 28) Expand Referenced Message

Walgreens around here are completely overwhelmed and are not open on weekends. They are not like that with newcomers and I asked if they had a medicine in short supply and I could barely get to the counter.

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Sunset Says:

Re: Renee (# 26) Expand Referenced Message

I was on Watson did fine and now the discontinuation and I am on Teva and it feels like I am taking nothing.

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Sunset Says:

Re: brian (# 23) Expand Referenced Message

Was on Watson, now they are no longer making it and have changed to Teva and I am in withdrawal. You also cannot cut the Teva to decrease your dose.

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Jack Says:

Anyone ever try Ativan from Pakistan or Iran 2mg. Cuz I got o2o Roche clonazepam from Pakistan n it was awesome.

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Wez Says:

Re: Penny (# 1) Expand Referenced Message

Amen, me too. What did you, and how do we find Mylan pharmaceutical

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Landers Says:

Re: Deedee (# 508) Expand Referenced Message

Spot on. I take 8mg of ativan daily for the last 8 years. Taking that low of a dose i wouldn't panic. Keep getting the smaller MG until u cant.

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Cherry Says:

Re: Erkle 57 (# 2) Expand Referenced Message

Can you tell me the milligram of a Lorazepam that is a small white round pill with the capital letters E-P and underneath the number 905? It's a Lorazepam but I don't know what the milligram is. Please let me know. {edited for privacy}

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Landers Says:

Re: Betsyjane34 (# 521) Expand Referenced Message

I am not sure what is going on as far as Teva buying out Watson. I will research it. The last 3 refills I have gotten Leading Pharma brand and they are total junk. It had no sedative effects. And it takes the edge off sometimes. It's hit or miss. I have told my pharmacy to order me the Watson's and they said they would so if they were bought out this pharmacist didn't know it. I'll keep posting updates.

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