Syndopa Plus & Pramipex .5


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Hi Experts,

My father is suffering from Parkinson disease from last 5 years approx. Till last Dec-2014, he is taking the below medicine:
- Syndopa 110 (Half medecine - thrice a day)
- Pramipex 0.5 (2 tablets a day)

Now on 04 - Jan - 2015 due to arthritis problem, we have replaced his both knees - To recover from Knee surgery easily - Doctors (Nero expert) suggested to follow below medicine:
- Syndopa Pluc ( one tablet - thrice a day)
- Pramipex .05 ( One tablet - twice a day)

(Also instructed us -- there must be a gap of approx. 1 hour between administering syndopa and pramipex medicine)

Now i realized that from last 2 months (Post operation and change in medicine) my father is some time not even recognizing me, even every time in a day i need to guide him again the way to wash room and more), most of time i need to tell him whether it's day or night (am or pm).

Kindly guide what to do ? really too depressed i am...... :( till date no one guided me that i should give syndopa on a fixed time of day, no time deviations, no one guided me that there needed to be a gap of 1 hour approx. in giving syndopa and pramipex?

Please guide me on the uses of syndopa and pramipex... general instructions of giving these medications and I also want to know why the doctor changed Syndopa 110 to Syndopa Plus?

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