Fentanyl Does Not Last 48 Hours
(Newest posts first)

8 Replies Updated

Conversation Starter

Jeff Says:
I am currently on a Mylan Fentanyl patch 50mcg/hr. I was on 75mcg patch which worked well with my pain but the patches dont last 48 hours. After about 30-36 hours I start having major withdrawel symptoms and pain. I had these withdrawels with both doses of the fentanyl patches. My dr dropped my down to 50mcg to see if it would help but it does'nt. I have some Dilaudid for breakthrough pain but it does'nt work at all for pain or withdrawel syptoms. The dilaudid is basically useless to me. Has anyone had a Mylan Fentanyl patch thats doing this?? I saw my dr today and he's considering taking me off the patches and back to the pills again. This really sucks. The patches have worked well for about 10 months now.

Showing Replies 8 - 1 of 8 ( Newest posts first ) RSS Feed

Page of 1     Sorted By:

Samo Says:
via mobile
I had the same problem, not only with mylan, but with all patches. My PMD had my take a lab test which confirmed my rate of metabolism for this med and then prescribed them for once daily use. It took a reasonable time for my insurance to preauthorize this non label use, but I have changed patches every day since then and have no problems.

Post a Reply   Share page   Report post

Was this helpful?  1 0  
Juls Says:
Hi. Sorry to hear of your troubles.I wonder if your patch is adhering properly. Mine were only lasting 48 hrs. I spoke to doc about having some withdrawal symptoms, and he thought that may be the issue. I seem to have these issues with the long acting forms of meds..the 12 hr would have to be prescribed every 8, even though I was only getting a good 6 hrs! So he asked if I wanted to increase from 75mcg to 100. I asked if I could instead use the 75 for 48 hrs instead and thankfully, he OK d this. I use the Tegraderm covering on top of the patch as soon as I 'be applied it. It seems to be working well. I even surprised myself by declining an increase in break thru meds. I prefer the Watson brand, though I hear Mylan is good also. I have been using the patch for 2 mos, tho had used them 20 yes prior. I definitely prefer this over all the pills, which just were not working anymore. I wish you the best!

Post a Reply   Share page   Report post

Was this helpful?  0 0  
Butterfli Says:
My PMD had me on the Duragesic (name brand Fentanyl) 100's...I lost about 48 lbs in less than a month and cold turkeyed myself off them as I was HIGHLY overmedicated then..he was always adamant about using the name brand only,which has the gel inside of it and the membrane on the back. I was able to go about 3 months without using them ( I do take Norco name brand 7.5's 8 daily tho). When I needed to go back onto the Fentanyl I would only let him start me back on the 25's and when I went to fill them they did not have the name brand in stock so I agreed they could give me the generics. They gave me the Mylan ones,which I really liked much better without the gel...I firmly believe that the gel ones aren't as good at administering the med into my body because the gel is constantly moving around and not laying flush with the skin. As time went by I was given other generics at times...one had the gel and most recently I was given the Mallinckrodt by a pharmacy without my knowledge which is AWFUL cause it's made like a really stiff plastic. Currently I am only back up to the 50's (7 yrs later from starting back on the 25's) and I change them every 48 hours. I request the Mylan brand generic because I love the way I feel it evenly administers the med into my body. Even had to argue with the doc years back to get him to write my rx's for the generics! I know that the fentanyl peaks at 18 hrs and then tapers down and thus the need for our "breakthrough meds". With the experience with all the other generics IMHO the Mylan is def the best generic on the market. I can tell you that the Mallinckrodt's short on me in about 36-40 hours and I feel like I accidently went to bed and forgot to change mine the night before...like I've gone over my time by about 12 hours and am sick and having wd symptoms. I hope that your dr can work something out with yours for you maybe adding a 12.5 to your regimen and possibly having you put it on the opposite days of your current ones (thus maybe adding just enuf for you not to have that wd feeling period) Good luck and God bless.

Post a Reply   Share page   Report post

Was this helpful?  0 0  
via mobile
Yes yes yes!!! I have taken other patches but was getting rash- so I use MYLAN brand!!! Have noticed withdrawal symptoms from some of these patches after having had on for just 24 hours!!' It is hard to tell a defective MYLAN patch since the Fentynol is not visible as with the other ones!!! I will prob be calling them tmo cuz went thru a box of five in less then 8 days cuz definitely could tell was experiencing withdrawal symptoms!!! Call Milan and be sure to have lot # located on box or patch packaging!!' I love the MYLAN brand cuz doesn't cause rash but really think that some patches DO NOT have the dose stated on package!! Have been on duregesic for over 10 years so I KNOW when there is an issue... Went thru withdrawal once due to hospital negligence and KNOW symptoms!!!

Post a Reply   Share page   Report post

Was this helpful?  1 0  
Jeff Krout Says:
Unfortunately morphine has no effect on me. So thats that. I'm just suprised my patches are'nt doing what they should any more. If this keeps up, I'll just get a Medtronic pump and do away with all the other junk.

Post a Reply   Share page   Report post

Was this helpful?  0 0  
Verwon Says:
Jeff, that is correct, the controlled release Oxycodone is only available as the name brand Oxycontin.

However, Morphine is available in a time released formulation as a generic, the name brand for it would be MS Contin, so you may want to talk to your doctor about trying it.


Is there anything else I can help with?

Post a Reply   Share page   Report post

Was this helpful?  0 0  
Jeff Krout Says:
I actually got a new script today for Oxycodone SR 30mg. Unfortunatley its not available in generic form so my insurance wont cover it. I'll just have to tough it out this weekend and see what the dr will do on Monday. Not sure what my options are for something extended release. I'm not looking forward to taking the hcl every 4 hours.

Post a Reply   Share page   Report post

Was this helpful?  0 0  
Verwon Says:
Very sorry for what you are going through.

It is possible that you have already built up a tolerance to them, or that you simply absorb the medication too fast.

The medication can also be absorbed faster than normal if you are in a very warm environment, or are overheated.


What pills is he thinking of putting you on?

Post a Reply   Share page   Report post

Was this helpful?  0 0  

Possibly Related Threads:

I started the fentanyl patch 100 today after 3 years of OxyContin, the last dose of Oxy was 80OP 4 times per 24 hours. How does the patch fair? Hello, friends! I started the Fentanyl patch 100mc today after OxyContin treatment my highest dose was 80OP up to 4 per ... 4 replies
Does 100 mg morphine sulfate extended release pill taken every twelve hours (2 per day) equal 100 mcg. Fentanyl patch applied every 48 hrs.? My question concerns drug conversion. The Fentanyl works well, most of time, for my chronic pain, but my insurance now s... 7 replies
if used for 60 hours how long does it take fentanyl to cause withdrawal IF I ONLY USED TWO 50 MCG FENTANYL PATCHES, REMOVED THEN WITH SIXTY HOURS, HOW LONG WILL IT BE IN MY SYSTEM? ## Hello, O... 2 replies
How long does a Mylan 12mcg fentanyl patch really last? I am new to fentanyl treatment but no stranger to narcotic treatment for severe sciatica in my left leg. I was prescribe... 1 reply
how do I stop not able to controll movements after being on fentanyl patch 50mcg hr dr said waith a couple hours before taking oxycontin 30mg which i I am 72 and been on a fentanyl patch 50 mcg/hr for 9 months for sever back pain the dr thought it was no longer working ... 6 replies
Hello Ive Been On The Fentanyl Patchfor About 11 Years Starting At 25 Mcg Now 75 For Last 2 Yearsthe Problem Is It Does Help But Pain Iam I Besides being on the patch. It seems after the second day on. the night before I chang it every 3 days. I have much pain... 11 replies
Morphine does not work on me will fentanyl patch work Morphine does not work on me will fentanyl patch work right now I am taking oxycodone 30 milligram 6 times a day for the... 2 replies
i know fentanyl is supposed to be stronger than morphine however it does not control my severe back pain as well the ms continental 100 mg tr tid I know Fentanyl is supposed to be stronger than Morphine however it does not help me near as much! !! I wish so bad that... 6 replies
fentanyl withdrawal after 36 hours of use My mother was given a fentanyl patch (25mg/hr) after receiving radiation treatment for a cancerous tumour in her spine. ... 3 replies
Fentanyl patches turning pink within hours and falling off My father has recently started on these patches after a second full knee replacement and being on other pain killers for... 1 reply

Post a Reply

No registration is needed.
Simply fill out the form below.

Please be detailed.

You may use your first name, or for more privacy, make up a nickname.

Optional. Always hidden. This allows us to notify you when a reply is posted here.

- Health News Headlines + Free RX Savings Card

4) Word Verification: *
Prevents SPAM.

Click here to show the question

This form will be submitted securely
I'm on a public or shared computer

Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.