Active Ingredient(s): Tenecteplase, TNK-tPA
FDA Approved: * June 2, 2000
Pharm Company: * GENENTECH
Category: Heart (Cardiac)

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

TNKase Overview

Tenecteplase (sold under the trade names TNKase Metalyse and Elaxim ) is an enzyme used as a thrombolytic drug. Tenecteplase is a tissue plasminogen activator (tPA) produced by recombinant DNA technology using an established mammalian cell line (Chinese hamster ovary cells). Tenecteplase is a 527 amino acid glycoprotein developed by introducing the following modifications to the complementary DNA (cDNA) for natural human tPA: a substitution of threonine 103 with asparagine, and a substitut...

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Possible Dosages for this and Related Drugs:

Tenecteplase, TNK-tPA
  • Injection: 50mg
  • Vial: 50mg/vial
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for TNKase: (2 results)

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Other drugs which contain Tenecteplase, TNK-tPA or a similar ingredient: (1 result)