Simponi

Active Ingredient(s): Golimumab
FDA Approved: * April 24, 2009
Pharm Company: * CENTOCOR ORTHO BIOTECH INC
Category: Arthritis

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Simponi Overview

Golimumab (CNTO 148)[1] is a human monoclonal antibody which is used as an immunosuppressive drug and marketed under the brand name Simponi. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule[2] and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellaular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor (VEGF) demon...

Read more Simponi Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Golimumab

Recent Simponi Forums: RSS Feed

simponi usage

Is anybody get 150 ml infusion of simponi every two month? ## Hello, Felbons! How are you? Simponi is used to treat health conditions, such as RA, psoriatic arthritis and ulcerative colitis, as listed by the FDA. Possible side effects may include chills, night sweats, dry cough, skin rash and loss of appetite. Can anyone that's been on it chime in with their experiences? Have you started it already? If so, how are you doing on it? These medications work great for some people, but many others do seem to have problems with them. It really just varies from person to person.

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new drug

is Simponi better or not than embrel ## I used embrel for six months with no improvement. After a few of taking simponi along with methotrexate I have had great improvement. Its like a wonder drug for me. ## Hi I've just had my first injection today have tried Embrel for about 8 months to no avail, I have Rheumatoid Arthritis. After the Embrel I was then put on Humira and had sever reactions to this injection. Now trialling this Anti-TNF. praying that it works and I don't have any sever reactions as with Humira . It's my 4th biological medication now, 1st one Actemera was successful but was taken off due to some side effects. It's a really new drug hear in Australia with very strict guidelines on critera of those whom are given authority to take it.

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Possible Dosages for this and Related Drugs:

Golimumab
  • Injection: 50mg, 50mg/4ml
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Simponi: (2 results)

Sorted by National Drug Code
  • 57894-070 Simponi 50 mg/.5ml Subcutaneous Injection, Solution by Janssen Biotech, Inc.
  • 57894-071 Simponi 100 mg/ml Subcutaneous Injection, Solution by Janssen Biotech, Inc.

Other drugs which contain Golimumab or a similar ingredient: (2 results)

Related Simponi Topics:

simponi usage
Is anybody get 150 ml infusion of simponi every two month? ## Hello, Felbons! How are you? Simponi is used to treat heal... 1 reply
Intestinal bleeding from Simponi Aria
I just started simponi aria infusion 2 mos ago, Just got my second infusion, immediately the next day I started bleeding... 2 replies
Simponi
number of patient treated by simponi ## I take Simponi for Ankylosing Spondylitis and now I have Poison Ivy - what can I... 1 reply






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