Simponi

Active Ingredient(s): Golimumab
FDA Approved: * April 24, 2009
Pharm Company: * CENTOCOR ORTHO BIOTECH INC
Category: Arthritis

Golimumab is a human monoclonal antibody which is used as an immunosuppressive medication and sold under the brand name Simponi. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule[5] and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellaular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor (VEGF) demonstrates golimumab as an effe... [wikipedia]

* May have multiple approval dates, manufacturers, or labelers.
3 Discussions

Dosage List

Simponi 50 mg/.5ml Subcutaneous Injection, Solution
NDC: 57894-070
Labeler:
Janssen Biotech, Inc.
Simponi 100 mg/ml Subcutaneous Injection, Solution
NDC: 57894-071
Labeler:
Janssen Biotech, Inc.

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