Active Ingredient(s):Methylnaltrexone Bromide FDA Approved: * April 24, 2008 Pharm Company: *PROGENICS PHARMA Category:Laxative
Methylnaltrexone (MNTX, brand name Relistor), used in form of methylnaltrexone bromide (INN, USAN, BAN), is a medication that acts as a peripherally acting μ-opioid receptor antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without significantly affecting pain relief or precipitating withdrawals. Because MNTX is a quaternary ammonium cation, it cannot cross the blood–brain barrier, and so has antagonist effects throughout the body, counte...
* May have multiple approval dates, manufacturers, or labelers. 3 Discussions