Palbociclib

Category: Cancer

Palbociclib Overview

Palbociclib (codenamed PD-0332991, trade name Ibrance) is a drug for the treatment of HR-positive and HER2-negative breast cancer developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.[1][2] Palbociclib was the first CDK4/6 inhibitor to be approved as a cancer therapy.[3] Contents 1 Mechanism of action 2 Administration 3 Approvals and indications 3.1 HR+ breast cancer 4 Mechanisms of Resistance 4....

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Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Palbociclib

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• IBRANCE Palbociclib