MigranalActive Ingredient(s): Dihydroergotamine
FDA Approved: * December 8, 1997
Pharm Company: * VALEANT
Category: Migraine / Tension Headache
Dihydroergotamine (DHE), sold under the brand names D.H.E. 45 and Migranal among others, is an ergot alkaloid used to treat migraines. It is a derivative of ergotamine. It is administered as a nasal spray or injection and has an efficacy similar to that of sumatriptan. Nausea is a common side effect. It has similar actions to the triptans, acting as an agonist to the serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but a... [wikipedia]* May have multiple approval dates, manufacturers, or labelers.