Estring
Active Ingredient(s): EstradiolFDA Approved: * April 26, 1996
Pharm Company: * PHARMACIA AND UPJOHN
Category: Women's Health / Fertility
* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".
Estring Overview
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips, and a female-associated pattern of fat distribution and is important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus,...
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Estradiol
Recent Estring Forums: 
How Long can you safely remove estring if needed
I had to take my ring out for a week due to an yeast infection.I washed the ring really good and dried it off put in plastic bag and put in a drawer. I called the company and they had no answers on how long it could be out ,there are no studies at $600 a ring I rinsed it off good and put it back in. Has anyone else done this
Updated
I had to take my ring out for a week due to an yeast infection.I washed the ring really good and dried it off put in plastic bag and put in a drawer. I called the company and they had no answers on how long it could be out ,there are no studies at $600 a ring I rinsed it off good and put it back in. Has anyone else done this
Updated
Estring stuck
I've only used one Estring so far, and it is time to change it. But it feels stuck when I hook my finger around it & tug on it. I can push part of the ring away from the vaginal wall lower down, but it won't budge from higher up. It totally helped my symptoms & I want to put in a new ring, but I don't know what to do. I hate to have to go to my gyne for this Any suggestions? ## I have difficulty removing the estring because my uterus is retro verged and my fingers are too short to reach. Easy solution, bear down like you are constipated and the ring moves down to where you can reach it! ## I usually struggle to get my ring out to change it, but this time was a real bear. Usually if I can get a finger under the edge, I can loosen it enough to pull it out, but not this...
Updated
I've only used one Estring so far, and it is time to change it. But it feels stuck when I hook my finger around it & tug on it. I can push part of the ring away from the vaginal wall lower down, but it won't budge from higher up. It totally helped my symptoms & I want to put in a new ring, but I don't know what to do. I hate to have to go to my gyne for this Any suggestions? ## I have difficulty removing the estring because my uterus is retro verged and my fingers are too short to reach. Easy solution, bear down like you are constipated and the ring moves down to where you can reach it! ## I usually struggle to get my ring out to change it, but this time was a real bear. Usually if I can get a finger under the edge, I can loosen it enough to pull it out, but not this...
Updated
Removing Estring
I can't reach far enough to remove my estring - I can barely touch it but not hook on to remove - any suggestions? ## Did you resolve this issue? For future reference, if you are unable to remove it, you should contact your doctor, or go to your nearest urgent care facility, where they can assist you. ## I can not remove my estring. I have tried but can not reach it... ## I removed the estring and forgot to reinsert it for about 22 hours. Is it still effective? ## Is there any harm in the Estring staying in for 2 weeks past 90 days? I cant get an rx appt any earlier and am totally frustrated that I cant remove it! ## My Gynecologist prescribed Estring due to my prolapse. I used the Estring on Nov 17th and on Dec 6th after almost 3 weeks, I removed it because of breast pain. Today is...
Updated
I can't reach far enough to remove my estring - I can barely touch it but not hook on to remove - any suggestions? ## Did you resolve this issue? For future reference, if you are unable to remove it, you should contact your doctor, or go to your nearest urgent care facility, where they can assist you. ## I can not remove my estring. I have tried but can not reach it... ## I removed the estring and forgot to reinsert it for about 22 hours. Is it still effective? ## Is there any harm in the Estring staying in for 2 weeks past 90 days? I cant get an rx appt any earlier and am totally frustrated that I cant remove it! ## My Gynecologist prescribed Estring due to my prolapse. I used the Estring on Nov 17th and on Dec 6th after almost 3 weeks, I removed it because of breast pain. Today is...
Updated
Estring moves-uncomfortable
Ive been using the estring for about 1.5 years. I'm happy with it as far as relieving itching etc. but lately it is uncomfortable and seems to move around when I move and just doesn't feel good when I walk. Any suggestions. I have a dropped uterus. ## Hello Cherie oh, Really the only advice to give in this situation is to talk about it with your primary care doctor or OBGYN. I'm glad that it relieves your itching but if it has become uncomfortable it could be caused by a physical change or something to do with the ring shifting. Only a doctor would really be able to give you a reliable and accurate answer. Good luck hope you get this resolved soon.
Updated
Ive been using the estring for about 1.5 years. I'm happy with it as far as relieving itching etc. but lately it is uncomfortable and seems to move around when I move and just doesn't feel good when I walk. Any suggestions. I have a dropped uterus. ## Hello Cherie oh, Really the only advice to give in this situation is to talk about it with your primary care doctor or OBGYN. I'm glad that it relieves your itching but if it has become uncomfortable it could be caused by a physical change or something to do with the ring shifting. Only a doctor would really be able to give you a reliable and accurate answer. Good luck hope you get this resolved soon.
Updated
Estring questions about side effects
Has anyone been hit with constipation after starting to use estring? So strange, but that's the only change that I can pinpoint to have affected things. Also, is anyone experiencing a successful diet experience as a result? I am having better luck than ever losing weight and controlling my appetite. I'm just trying to figure out if either of these things are due to the extra estrogen. ## Hello, Attie! How are you? Constipation can happen due to the slightest change in your body, so yes, that's highly possible. Other side effects, as listed by the FDA, may possibly include nausea, dizziness, headache, irritability, breakthrough bleeding and PMS-like symptoms. The losing weight, however, is unusual, as these usually tend to cause weight gain. Have you experienced any other sid...
Updated
Has anyone been hit with constipation after starting to use estring? So strange, but that's the only change that I can pinpoint to have affected things. Also, is anyone experiencing a successful diet experience as a result? I am having better luck than ever losing weight and controlling my appetite. I'm just trying to figure out if either of these things are due to the extra estrogen. ## Hello, Attie! How are you? Constipation can happen due to the slightest change in your body, so yes, that's highly possible. Other side effects, as listed by the FDA, may possibly include nausea, dizziness, headache, irritability, breakthrough bleeding and PMS-like symptoms. The losing weight, however, is unusual, as these usually tend to cause weight gain. Have you experienced any other sid...
Updated
what is the differance between vaginal ring estring estradiol and femring acetate?
I am using Femring now and wonder if I could change to Estring if it might cost less? My insurance doesn't cover Femring, I've had breast cancer and told this was the best way for me to get hormone replacement safely. ## It is always best to follow your doctor's instructions. The typical side effects may possibly include dizziness, headache, nausea, mood changes, weight changes, and irregular bleeding. They both really do the same thing, which is preventing pregnancy. Which one have you chosen to try?
Updated
I am using Femring now and wonder if I could change to Estring if it might cost less? My insurance doesn't cover Femring, I've had breast cancer and told this was the best way for me to get hormone replacement safely. ## It is always best to follow your doctor's instructions. The typical side effects may possibly include dizziness, headache, nausea, mood changes, weight changes, and irregular bleeding. They both really do the same thing, which is preventing pregnancy. Which one have you chosen to try?
Updated
Stomach problems
I inserted the Estring and within two hours had diarrhea and cramping, then chills. I kept it in for six more hours but was really feeling sick, so removed it. Literally felt better within the hour. I'd like to try it again but wonder if this would likely be a permanent issue or if this stomach thing will resolve itself as my body gets used to it? ## Those can be side effects of using a hormonal supplement, and it may take about 3 months for them to go away, according to FDA reports. Other side effects can include mood changes, weight changes, and irritability. Have you tried it, again? Are you on any other medications? How old are you?
Updated
I inserted the Estring and within two hours had diarrhea and cramping, then chills. I kept it in for six more hours but was really feeling sick, so removed it. Literally felt better within the hour. I'd like to try it again but wonder if this would likely be a permanent issue or if this stomach thing will resolve itself as my body gets used to it? ## Those can be side effects of using a hormonal supplement, and it may take about 3 months for them to go away, according to FDA reports. Other side effects can include mood changes, weight changes, and irritability. Have you tried it, again? Are you on any other medications? How old are you?
Updated
Difficult removing and white substance on part of ring
I have been using Estring for several years and it has really helped with my vaginal dryness. The last time I went to take it out and replace it the Ring was very hard to remove. I pulled it loose from the vaginal wall and when I looked at it it had some white substance on it. I wasn't sure what that meant if anything. Since it has always been clean and easy to take out I wanted to find out if it was something to be concerned about or not. I have not put a new one in and won't until I get some answers. U ## How easy or hard it is to remove can depend on your hormonal cycle, since your cervix moves up and down throughout the month. Thus, if you're having a different hormonal surge, when the time comes to remove it, it could be harder to remove than at other times, as reported...
Updated
I have been using Estring for several years and it has really helped with my vaginal dryness. The last time I went to take it out and replace it the Ring was very hard to remove. I pulled it loose from the vaginal wall and when I looked at it it had some white substance on it. I wasn't sure what that meant if anything. Since it has always been clean and easy to take out I wanted to find out if it was something to be concerned about or not. I have not put a new one in and won't until I get some answers. U ## How easy or hard it is to remove can depend on your hormonal cycle, since your cervix moves up and down throughout the month. Thus, if you're having a different hormonal surge, when the time comes to remove it, it could be harder to remove than at other times, as reported...
Updated
Muscle Pain and coughing
I started the Estring after I went into menopause from Chemotherapy. I started to feel a heaviness in my chest, coughing and a lot of mucous along with muscle pain. I contacted my OB and she said she didn't think the symptoms I had were from the Estring. Did anyone else have these symptoms? ## The chest tightness is actually listed by the FDA as being possible allergic reaction, which could also encompass coughing and etc. How long have you been on it? Are you still on any other medications? Has there been any change? Have the symptoms worsened, or improved? ## Shortness of breath is a serious side effect (it looks like SOB from your symptoms. That's an allergic reaction and you should stop (I'm not a doctor, but I've had similar symptoms with other drugs)
Updated
I started the Estring after I went into menopause from Chemotherapy. I started to feel a heaviness in my chest, coughing and a lot of mucous along with muscle pain. I contacted my OB and she said she didn't think the symptoms I had were from the Estring. Did anyone else have these symptoms? ## The chest tightness is actually listed by the FDA as being possible allergic reaction, which could also encompass coughing and etc. How long have you been on it? Are you still on any other medications? Has there been any change? Have the symptoms worsened, or improved? ## Shortness of breath is a serious side effect (it looks like SOB from your symptoms. That's an allergic reaction and you should stop (I'm not a doctor, but I've had similar symptoms with other drugs)
Updated
Length of use?
I've been on Estring over 10 years with absolutely no negative side effects. Of course 15 lbs heavier but could be many factors, less active, wine etc! My question if anyone has ever heard of this is, has anyone heard of using this for such a long time. I once stopped for a couple of months and began the sweating, fogginess and the same feeling as if I were going through menopause again. My doctor seems to think I can use it indefinitely. Also mother and sister have had great cancer. ## Hello, Janet! How are you? The FDA warns that it does carry the same risks as hormonal contraceptives, including several types of cancer. The most common side effects are listed as possibly including headaches, increased secretions, and itching. It is normal, however, to experience such symptoms due ...
Updated
I've been on Estring over 10 years with absolutely no negative side effects. Of course 15 lbs heavier but could be many factors, less active, wine etc! My question if anyone has ever heard of this is, has anyone heard of using this for such a long time. I once stopped for a couple of months and began the sweating, fogginess and the same feeling as if I were going through menopause again. My doctor seems to think I can use it indefinitely. Also mother and sister have had great cancer. ## Hello, Janet! How are you? The FDA warns that it does carry the same risks as hormonal contraceptives, including several types of cancer. The most common side effects are listed as possibly including headaches, increased secretions, and itching. It is normal, however, to experience such symptoms due ...
Updated
Possible Dosages for this and Related Drugs:
Estradiol
- Cream: 0.01%
- Emulsion: 0.25%, 2.5mg/g
- Film, Extended Release: 0.014mg/24hr, 0.025mg/24hr, 0.025mg/day, 0.0375mg/24hr, 0.05mg/24hr, 0.06mg/24hr, 0.075mg/24hr, 0.1mg/24hr, n/a
- Gel: 0.06%, 0.1%, 0.1% (0.25gm/packet), 0.1% (0.25mg/packet), 0.1% (0.5gm/packet), 0.1% (0.5mg/packet), 0.1% (1gm/packet), 0.1% (1mg/packet)
- Gel, Metered: 0.06%, 0.06% (0.87gm/activation), 0.06% (1.25gm/activation)
- Injection: 10mg/ml, 1mg/ml, 20mg/ml, 3mg/ml, 40mg/ml, 5mg/ml
- Insert: 0.004mg, 0.01mg
- Insert, Extended Release: 0.0075mg/24hr, 0.05mg/24hr, 0.1mg/24hr, 2mg
- Powder: 100%
- Spray: 1.53mg/spray
- System: 0.014mg/24hr, 0.025mg/24hr, 0.025mg/day, 0.0375mg/24hr, 0.0375mg/day, 0.05mg/24hr, 0.05mg/day, 0.075mg/24hr, 0.075mg/day, 0.1mg/24hr, 0.1mg/day
- Tablet: 0.45mg, 0.5mg, 0.9mg, 1.5mg, 1.8mg, 10mcg, 10ugm, 1mg, 25mcg, 25mcg + 25ugm, 25ugm, 2mg
NDC Database Records for Estring: (3 results)
Sorted by National Drug Code- 0013-2150 Estring 2 mg/1 Vaginal Ring by Pharmacia and Upjohn Company
- 54868-5538 Estring 2 mg/1 Vaginal Ring by Physicians Total Care, Inc.
- 63539-021 Estring 2 mg/1 Vaginal Ring by U.S. Pharmaceuticals
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- ORTHO TRI-CYCLEN LO Ethinyl Estradiol + Norgestimate1 discussion
- ORTHO-CEPT Ethinyl Estradiol + Desogestrel2 discussions
- ORTHO-CYCLEN Ethinyl Estradiol + Norgestimate1 discussion
- ORTHO-NOVUM 1/35-28 Ethinyl Estradiol + Norethindrone
- ORTHO-NOVUM 10/11-28 Ethinyl Estradiol + Norethindrone
- ORTHO-NOVUM 7/7/7-28 Ethinyl Estradiol + Norethindrone1 discussion
- ORTHO-PREFEST Estradiol + Norgestimate1 discussion
- ORTHO-TRI-CYCLEN Ethinyl Estradiol + Norgestimate2 discussions
- OVCON 50 Ethinyl Estradiol + Norethindrone
- OVCON-35 Ethinyl Estradiol + Norethindrone
- OVRAL-28 Ethinyl Estradiol + Norgestrel2 discussions
- PHILITH Ethinyl Estradiol + Norethindrone1 discussion
- PIMTREA Desogestrel + Ethinyl Estradiol
- PIRMELLA 1/35 Ethinyl Estradiol + Norethindrone
- PIRMELLA 7/7/7 Ethinyl Estradiol + Norethindrone
- PORTIA-21 Ethinyl Estradiol + Levonorgestrel
- PREVEN Ethinyl Estradiol + Levonorgestrel3 discussions
- PREVIFEM Ethinyl Estradiol + Norgestimate9 discussions
- QUARTETTE Ethinyl Estradiol + Levonorgestrel
- QUASENSE Ethinyl Estradiol + Levonorgestrel4 discussions
- SAFYRAL Drospirenone + Ethinyl Estradiol + Levomefolate Calcium1 discussion
- SEASONALE Ethinyl Estradiol + Levonorgestrel1 discussion
- SEASONIQUE Levonorgestrel + Ethinyl Estradiol2 discussions
- SEGESTERONE ACETATE + ETHINYL ESTRADIOL
- SETLAKIN Ethinyl Estradiol + Levonorgestrel1 discussion
- SIMPESSE Ethinyl Estradiol + Levonorgestrel
- SPRINTEC Ethinyl Estradiol + Norgestimate268 discussions
- SYEDA Drospirenone + Ethinyl Estradiol6 discussions
- SYLEVIA Ethinyl Estradiol + Levonorgestrel
- TRI LO SPRINTEC Ethinyl Estradiol + Norgestimate3 discussions
- TRI-ESTARYLLA Ethinyl Estradiol + Norgestimate
- TRI-LEGEST 21 Ethinyl Estradiol + Norethindrone Acetate
- TRI-LEGEST FE Ethinyl Estradiol + Norethindrone Acetate
- TRI-LEVLEN Ethinyl Estradiol + Levonorgestrel
- TRI-LINYAH Ethinyl Estradiol + Norgestimate3 discussions
- TRI-LO-ESTARYLLA Ethinyl Estradiol + Norgestimate
- TRI-LO-MILI Ethinyl Estradiol + Norgestimate
- TRI-MILI Ethinyl Estradiol + Norgestimate
- TRI-NORINYL Ethinyl Estradiol + Norethindrone
- TRI-PREVIFEM Ethinyl Estradiol + Norgestimate36 discussions
- TRI-SPRINTEC Ethinyl Estradiol + Norgestimate31 discussions
- TRINESSA Ethinyl Estradiol + Norgestimate11 discussions
- TRIPHASIL-28 Ethinyl Estradiol + Levonorgestrel
- TRIVORA Ethinyl Estradiol + Levonorgestrel2 discussions
- TWIRLA Levonorgestrel + Ethinyl Estradiol
- TYBLUME Ethinyl Estradiol + Levonorgestrel
- TYDEMY Drospirenone + Ethinyl Estradiol + Levomefolate Calcium
- VALERTEST Estradiol + Testosterone
- VELIVET Ethinyl Estradiol + Desogestrel
- VIENVA Ethinyl Estradiol + Levonorgestrel
- VOLNEA Desogestrel + Ethinyl Estradiol
- VYFEMLA Ethinyl Estradiol + Norethindrone
- WERA Ethinyl Estradiol + Norethindrone4 discussions
- XULANE Ethinyl Estradiol + Norelgestromin7 discussions
- YAELA Drospirenone + Ethinyl Estradiol
- YASMIN Drospirenone + Ethinyl Estradiol29 discussions
- YAZ Drospirenone + Ethinyl Estradiol31 discussions
- ZOVIA 1/35E Ethinyl Estradiol + Ethynodiol Diacetate
- ZOVIA 1/50E Ethinyl Estradiol + Ethynodiol Diacetate
- ZUMANDIMINE Drospirenone + Ethinyl Estradiol
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