Durezol

Active Ingredient(s): Difluprednate
FDA Approved: * June 23, 2008
Pharm Company: * SIRION THERAPEUTICS
Category: Vision / Eye Health

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Durezol Overview

Difluprednate is a corticosteroid, It is chemically a butyrate ester of 6(alpha),9(alpha)-difluoro prednisolone acetate. Accordingly, difluprednate is sometimes abbreviated DFBA, for difluoroprednisolone butyrate acetate. Approval On June 24, 2008, the US Food and Drug Administration (FDA) approved difluprednate for the treatment of post-operative ocular inflammation and pain.[1] It is marketed by Alcon under the tradename Durezol. Clinical trials Difluprednate ophthalmi...

Read more Durezol Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Difluprednate

Recent Durezol Forums: RSS Feed

durezol and weight gain

I have been on Durezol drops 6x day for over a year and have gained 20 pounds! My IOP was so low that they could not get a reading and the Durezol is being used to increase the pressure. I will be on them indefinitely. Not happy about the weight gain. ## The FDA classifies this as a steroid class medication, so weight gain can be a typical side effect of it, along with dizziness, headache, eye irritation and acne. Are you also watching your diet and getting plenty of exercise? Such actions may help to mitigate the weight gain. ## Please get a second opinion asap. Durezol is not intended for that high of a dose. It is very strong and will increase inflammation and eye damage which actually lowers the eye pressure causing hypotony. This happened in my case and also caused macular edema. T...

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Act cataract surgery and eye drop side effects

after using dorezol drops I begin having nervousness feelings and anxiety I couldn't deal with anything or anybody. I also gained waiting for those 3 weeks or more. has anyone else have this problem? ## Durezol contains the active ingredient Difulprednate, which is a steroid class medication, so the types of side effects you experienced are common, including the weight gain. Learn more Difulprednate details here. These types of side effects can occur with any steroid class medication that's used. Are there any other comments or questions? ## I have been using durezol now at twice per day for over five weeks after having cataract surgery in one eye and then another. I have been having crazy nausea this is the only new medication. Just wondering if this is possible? I am at a loss...

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DUREZOL EYE DROPS

I've been on Durezol for 1-1/2 years for Iritis. I've had 6 eye surgeries in 2 years-2 macular holes, 2 cataracts, 2 eye shunts because of high IOP. I've gained 17 lbs. When you drop Durezol then pinch your eyes, you still get Durezol running into your tear ducts which then goes right into your system. Can't be helped. But also because Durezol makes your vision blurry and your eyes light sensitive, I've not been as physically active as I was prior to my eye surgeries and I went into a little depression. I think that is reason for my weight gain and maybe others.

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durezol and visine?

Can I use durezol and visine? The durezol is burning my eyes ## The burning can be a normal side effect of Durezol, as listed by the FDA. You may also experience blurred vision, watery eyes and mild headache. However, I'd not recommend mixing it with the Visine, unless your doctor approves, since it could affect how much of the Durezol you absorb. Is there anything else I can help with?

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durezol eye drop and weight gain

I am also rapidly gaining weight and have several more weeks to go on Durezol. 8 lbs in the first 9 days. Does it stop or just keep going up? How long did it take you to lose it? ## Hello, Liberty! How are you? Since this is a topical steroid that's just placed into the eye, you don't usually absorb enough of it to cause weight gain and the FDA doesn't list it as a known side effect of the ophthalmic solution, those typical include eye redness, trouble seeing at night, blurred vision and dry eyes. I'm not saying it's impossible, but rather that it hasn't been known to happen, so far. Have you consulted your doctor? Are you on any other medications? ## Doctor did call back today and said it's not happening. My scale and I know it is. No other drugs. No suddenl...

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Durezol

I am type 2 diabetic, currently on Glipizide. On long term Prednizone for polymalgia rheumatica for 2 years. Just had cataract surgery and have been on Durezol for 2 weeks t.i.d. Blood sugars are very erratic since doing the eyedrops. MD says no interaction ! but something is going on. Eye surgeon says NOT the eyedrops. Any idea why this is happening ? ## The Durezol contains the active ingredient Difluprednate, which is another steroid class medication, just like the Prednisone. So yes, it could be causing the problem, especially if you are still taking the Prednisone, since it means that there are now more steroids in your body and they are known to have an effect on blood sugar levels. Have you doctors given you any ideas for resolution, such as adjusting your diabetes medication? ##...

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durezol Rebate?

Rebates Cost for Me is $45.00 co-pay ## Hi, George! How are you? I'm sorry, but I didn't find any rebates or discounts listed for Durezol. Learn more Durezol details here. Have you tried asking your doctor if there is a cheaper alternative that you can use?

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Possible Dosages for this and Related Drugs:

Difluprednate
  • Emulsion: 0.05%
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Durezol: (2 results)

Sorted by National Drug Code
  • 0065-9240 Durezol .5 mg/ml Ophthalmic Emulsion by Alcon Laboratories, Inc.
  • 54868-6296 Durezol .5 mg/ml Ophthalmic Emulsion by Physicians Total Care, Inc.

Other drugs which contain Difluprednate or a similar ingredient: (1 result)

Related Durezol Topics:

durezol eye drop and weight gain
I am also rapidly gaining weight and have several more weeks to go on Durezol. 8 lbs in the first 9 days. Does it stop o... 3 replies
durezol and weight gain
I have been on Durezol drops 6x day for over a year and have gained 20 pounds! My IOP was so low that they could not get... 2 replies
Durezol
I am type 2 diabetic, currently on Glipizide. On long term Prednizone for polymalgia rheumatica for 2 years. Just had ca... 2 replies
durezol and visine?
Can I use durezol and visine? The durezol is burning my eyes ## The burning can be a normal side effect of Durezol, as l... 1 reply
durezol Rebate?
Rebates Cost for Me is $45.00 co-pay ## Hi, George! How are you? I'm sorry, but I didn't find any rebates or dis... 1 reply
DUREZOL EYE DROPS
I've been on Durezol for 1-1/2 years for Iritis. I've had 6 eye surgeries in 2 years-2 macular holes, 2 cataract...




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