Contrave

Active Ingredient(s): Bupropion Hydrochloride + Naltrexone Hydrochloride
FDA Approved: * September 10, 2014
Pharm Company: * OREXIGEN THERAPEUTICS INC
Category: Diet / Weight Loss

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Contrave Overview

Bupropion/naltrexone is a combination drug used for weight loss in those that are either obese or overweight with some weight-related illnesses.[1][2] It combines low doses of bupropion and naltrexone. Both drugs have individually shown some evidence of effectiveness in weight loss, and the combination has been shown to have some synergistic effects on weight.[3] In September 2014, a sustained release formulation of the drug was approved for mar...

Read more Contrave Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Bupropion/naltrexone

Recent Contrave Forums: RSS Feed

Contrave and smelly urine

OMGOSH... I can not believe I am asking this, but.... I am on month 4 of Contrave and my urine has an odor. I have looked at the side effects and I do not see that as one of them.... Does anyone else have this issue or is it just me? ## Almost any medication can cause such a side effect, according to NIH studies, since you are adding a new chemical to your body. However, if you start experiencing other symptoms, such as pain, burning when urinating, or blood in your urine, please see your doctor, as soon as possible. Are you on any other medications? ## I’m having the same issue. Going to see doctor to make sure it isn’t another problem, but I’m almost positive it’s the Contrave. Started about a month in as well. ## Yes, yes, yes. I am entering my third month on ...

Updated
Contrave and Vomiting

I have been on Contrave for 3 months. I have battled nausea all along, hoping it would go away. I've lost 15 pounds. The pill seems to make everything taste bad. Coffee, spicy food, even just scrambled eggs taste bitter and gritty. I didn't have any other side effect. This past week, the nausea has moved on to vomiting. I've used Tumms and Dramamine as well as a prescription anti nausea med on and off for all three months. I truly feel poisoned. I feel ridiculous that I have used this knowingly for 3 months and endured feeling sick. I've spent a lot of money and feel terrible even a week after stopping the drug. Please don't take this. I feel that fairly soon enough folks will complain enough to take it off of the market. ## I dont feel that it should be taken off th...

Updated
contrave and sleepiness

I started contrave 4 days ago, today being my 5th dose. every day, i take the pill about 8am and by 9:30-10am I am so sleepy I can't stand it. Days 1 and 2 I managed to fight it off until about 12-12:30, day 3 until about 1-1:30, and day 4 I fought it off until 3pm. If I take a 1-2 hour nap, I wake up fine, with energy and then cannot get to sleep until about 2am, sometimes 3am. Today is day 5, I'm having that "drunk" feeling and sleepy, but no where near how it has been. It seems this effect is slowly wearing off, but I haven't seen anywhere where this is a common side effect. I know all medications effect everyone differently, so I'm wondering if this is something I should be concerned about, or just another side effect that I will get used to as the weeks go o...

Updated
Killer Headaches

I'm on Contrave almost 3 mos and lost 29 lbs...that's the great part, but lately I am getting the worst headaches, usually over one eye . Lately I've been getting 3 headaches a week and all I could do is lay in bed. Sometimes ice on my head feels better or even the pressure from the pillow being on my head to block out the light helps. I went to my prescribing doctor and she said headaches are a side effect. Other than a headaches my only other side effect is dry mouth. My doctor said the headache should go away as this does happen to a few patients on this meds. Advil migraine doesn't seem to help so I really don't know what else I could take with contrave. If I wasn't on contrave this kind of headache would definitely be gone with a Vicodin! But I know I cannot...

Updated
Contrave Dosage Question

My doctor prescribed to take this as 2 pills 2x per day. Not a ramp up like I read about online - has anyone else done this? I have not started taking the pills yet. ## You really should gradually increase it. It isn't fun gradually, it has to really suck taking it all at once. I would think it could hurt you taking it all straight away. The dr will write the rx for the full amount but either tell the pt to gradually increase or give them a sheet of paper. He gave me a pamphlet from the company that makes it. Ive found this to be common with other medicines that had to be brought up to a full dose over time. You should call and ask your doctor what you should do and tell them about the titration schedule. He may not know about it. I've had to inform my doctors about a lot of thi...

Updated
wanting to quit taking contrave

I need to know how to stop taking contrave. Can I just quit cold turkey or do I wean off? If I wean off how do I do it? ## Hello, Janice! How are you? How long have you been taking it? Why do you want to stop it? The FDA lists Contrave as being used to aid in weight loss and its typical side effects may possibly include nausea, dizziness, nervousness, insomnia and anorexia. Have you consulted your doctor? It does require slow tapering for some people. ## I was looking up how to wean myself off of Contrave and found this comment on here. I've been taking Confrave for about a month or so. I just started the 2 pills in the morning and 2 pills at night dose Sunday (today is Friday). I've felt horrible all week since increasing it. Hot flashes in my face, horrible nausea, glands some...

Updated
how long does it take to get contrave out of your system

I need to reduce my intake of Contrave because of side affects. I'm cutting back from 4 pills to 3. How long does it take for Contrave to reduce in my system so that I don't have the severe symptoms? ## Hello, Penni! How are you feeling? Has there been any improvement, yet? What side effects have you been experiencing? When it comes to this medication, it depends on which ingredient is causing the symptoms. The Naltrexone in it only takes about a day, but the Bupropion may take about a week, based on the FDA listed half-lives. ## I saw my doctor yesterday. We have reduced my dosage to 2 pills a day to see if that helps. If not than next week I'll go down to 1 a day. My worst symptoms out of several are hot flashes & nausea. ## I've only been taking contrave for a wee...

Updated
contrave not working anymore

I took Contrave and lost 52 pounds in 10 months, which has put me back to my ideal body weight. The problem is that it has not been working after that 10 months. I don’t have any side effects, but have a ridiculous appetite now. Almost to the point of wanting to binge eat. Anybody else been on it a while and have it stop working? I’ve gained almost 10 pounds back in the last few months. I’m not sure whether to ask my doctor about stopping it, but I’m afraid my appetite will be even worse. Anybody? ## I had the same problem. I was starving hungry and wanted to eat and eat. Weirdest thing was that I felt constantly hungry even after a week? ## You are not the only people who have experienced such issues. Most people who have tried it have reported eventually hittin...

Updated
contrave and cymbalta

On day two of Contrave but also on 30mg of cymbalta. My doctor didn't seem to have any worries on both together. Has anyone been on both. I actually skipped my cymbalta for last nights dose because I want off of cymbalta. I have been on 30mg since last November. Any personal experiences?? ## Hello, Erica! How are you? They can increase the toxicity of each other, as well as increasing the risk of seizures, when they are combined, according to the FDA. Thus, they should not normally be prescribed together and it is advised that this only be done as a last resort, when someone is out of other options. Is there anything else I can help with? ## I am wondering the same thing. I am also on cymbalta fornthe past month and a half and now i started contrave a week ago. Everything i read say...

Updated
Taking contrave a second time around

I recently took contrave for a year and had wonderful success! I had all the horrible side effects in the beginning and wanted to quit. I talked to my Dr and he lowered my dose and the intolerable side effects went away! I originally lost 65lbs now after stopping it, I've gained back 30 lbs. After a while though I reached a plateau and it stopped working my appetite came back and I started to gain. I've been off contrave for two months and was wondering if I restarted taking it would it begin to work once more? I guess my question is how long do I have to be off of it for it to be out of my system so that I can start fresh again? ## Most people do report hitting a plateau point, after being on it for awhile, and it usually takes a few months for it to start working, again. I...

Updated

Possible Dosages for this and Related Drugs:

Bupropion Hydrochloride + Naltrexone Hydrochloride
  • Tablet, Extended Release: 8mg + 90mg, 90mg + 8mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Contrave: (2 results)

Sorted by National Drug Code
  • 50090-2868 Contrave Oral Tablet, Film Coated, Extended Release by A-s Medication Solutions
  • 64764-890 Contrave Oral Tablet, Film Coated, Extended Release by Takeda Pharmaceuticals America, Inc.

Drugs with one or more similar ingredients: (5 results)

Related Contrave Topics:

contrave and sleepiness
I started contrave 4 days ago, today being my 5th dose. every day, i take the pill about 8am and by 9:30-10am I am so sl... 77 replies
Contrave vs Belviq
I was on free 2 weeks of Belviq followed by 1 mo out of pocket Belviq. Lost and felt good with NO side effects at all. T... 73 replies
Contrave and Suboxone
I started today with my first dose of contrave, 1 pill in the AM. I also take suboxone 8mg (4 1 time a day). My doctor s... 63 replies
Contrave and alcohol consumption
I have filled my prescription of Contrive but have not yet started taking it. I read all the possible side effects and a... 52 replies
Contrave and High Fat Foods
I ate a high fat meal (stuffed baked potato) tonight and am wondering when it is safe to take my evening dose of Contrav... 46 replies
Contrave / ringing in ears
Has anyone suffered from ringing in ears from Contrave? I'm going insane :(. but losing weight :) ## Hello, Jojo! Ho... 36 replies
Contrave and Vomiting
I have been on Contrave for 3 months. I have battled nausea all along, hoping it would go away. I've lost 15 pounds.... 23 replies
Contrave and appetite control
I'm currently on week 3 of Contrave (2 pills in the AM/1 in the PM). When should I possibly be noticing a decrease i... 20 replies
contrave not working anymore
I took Contrave and lost 52 pounds in 10 months, which has put me back to my ideal body weight. The problem is that it h... 13 replies
contrave and cymbalta
On day two of Contrave but also on 30mg of cymbalta. My doctor didn't seem to have any worries on both together. Has... 13 replies






Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 15 December 2018.

We are committed to your privacy.

Copyright © 2005-2018 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA