Contrave

Active Ingredient(s): Bupropion Hydrochloride + Naltrexone Hydrochloride
FDA Approved: * September 10, 2014
Pharm Company: * OREXIGEN THERAPEUTICS INC
Category: Diet / Weight Loss

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Contrave Overview

Bupropion/naltrexone is a combination drug used for weight loss in those that are either obese or overweight with some weight-related illnesses.[1][2] It combines low doses of bupropion and naltrexone. Both drugs have individually shown some evidence of effectiveness in weight loss, and the combination has been shown to have some synergistic effects on weight.[3] In September 2014, a sustained release formulation of the drug was approved for mar...

Read more Contrave Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Bupropion/naltrexone

Recent Contrave Forums: RSS Feed

contrave and cymbalta

On day two of Contrave but also on 30mg of cymbalta. My doctor didn't seem to have any worries on both together. Has anyone been on both. I actually skipped my cymbalta for last nights dose because I want off of cymbalta. I have been on 30mg since last November. Any personal experiences?? ## Hello, Erica! How are you? They can increase the toxicity of each other, as well as increasing the risk of seizures, when they are combined, according to the FDA. Thus, they should not normally be prescribed together and it is advised that this only be done as a last resort, when someone is out of other options. Is there anything else I can help with? ## I am wondering the same thing. I am also on cymbalta fornthe past month and a half and now i started contrave a week ago. Everything i read say...

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Taking contrave a second time around

I recently took contrave for a year and had wonderful success! I had all the horrible side effects in the beginning and wanted to quit. I talked to my Dr and he lowered my dose and the intolerable side effects went away! I originally lost 65lbs now after stopping it, I've gained back 30 lbs. After a while though I reached a plateau and it stopped working my appetite came back and I started to gain. I've been off contrave for two months and was wondering if I restarted taking it would it begin to work once more? I guess my question is how long do I have to be off of it for it to be out of my system so that I can start fresh again? ## Most people do report hitting a plateau point, after being on it for awhile, and it usually takes a few months for it to start working, again. I...

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Side effects of Contrave

I'm on my third day. Today I have a severe headache. But my question is this, has anyone had bad diarrhea? I get cramps, then bam. But I was feeling better by night. Today is the worst. Should I continue or stop? ## Hello, Shercon! How are you doing? I'm very sorry about the way you're feeling. Those can be normal side effects of Contrave and it may take about a month for them to wear off, as your body gets used to the medication. Other side effects, as listed by the FDA, may possibly include dry mouth, dizziness and nausea. Have you consulted your doctor? Unless they feel there is some reason to be concerned, you should most likely continue taking it. ## Verwon -- are you taking Contrave? ## I'm on Contrave and the stomach discomfort wore off, very mild headache left to...

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Just started Contrave

Wow, I took my first pill this morning and in an hour I had bad diarrhea. Was on my way to work and had to turn around and go home. An hour and half later and I'm still feeling stomach cramps. Am I going to have this problem every time I take the pill? Should I take the pill with food? I had eaten breakfast an hour earlier. Help, I don't know what to do. ## Yes!! and more!! I had the same problem, took the first pill and within a couple of hours I had nausea and diarrhea with vomiting to follow. After laying down I felt better until I got back in the car. The motion brought back not only the nausea but also dizziness. I can't use a product that leaves me unable to eat, drink or do anything but lay down for the entire day. ## Hello Cynthia, According to the NIH diarrhea is a ...

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Contrave and Restless Leg Syndrome

Has there been any studies or anecdotal information on Contrave and Restless Leg Syndrome? ## Hello Walt, According to the NIH restless leg syndrome is not an adverse reaction that is associated with this drug, however that does not mean that it's impossible for it to be the root cause. According to the report given by the FDA only 3 individuals out of 2,778 reported restless syndrome as a condition they noticed after taking contrave. Are there any other medications that you are taking in addition to the contrave?

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Contrave and birth control

I have been on contrave for about 5 months now and ever since I have had spotting while on birth control pills. I normally take them continously for 3 months and then have a cycle that last week but now it seems to be causing a cycle every month. Has anyone else had this problem? ## Irregular menstruation is reported by the FDA as a possible side effect of Contrave. You may also experience nausea, dizziness, headache and insomnia. Have any other women experienced this? ## Yes I suffer from chronic migraines and my medication has caused me major weight gain so as a counter measure my doctor prescribed contrave to kick start me I am going on week 3 and I really thought that somethings else had gone horribly wrong, my first week contrave causes me spotting then these past two weeks my migr...

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Itching from Contrave

I have been taking Contrave for three weeks and have developed itching on the insides of my hands and the bottoms of my feet. Has anyone else experienced this? ## Hello, Arlie! How are you? Do you have a rash, or just the itching? Contrave has been known to cause a rash as a side effect, as listed by the FDA. You may also experience nausea, dizziness, headache and insomnia. Are you on any other medications? The itching could be due to a circulation problem. ## No rash. No other meds. Nothing new besides the Contrave. ## There's a chance that it's affecting your circulation, which can cause itching. Have you had it checked out by your doctor, yet? Has it improved, at all? ## I have cut the dosage in half (one pill in the morning and one in the evening) and no longer have the itch...

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Contrave / ringing in ears

Has anyone suffered from ringing in ears from Contrave? I'm going insane :(. but losing weight :) ## Hello, Jojo! How are you? Yes, tinnitus is among the possible side effects that are listed by the FDA. Other symptoms you may experience could possibly include nausea, dizziness, constipation, headache, upper abdominal pain, irritability, rash and muscle strains. How long have you been taking it? Most side effects are transient and will taper off in severity as your body gets used to the medication and will go away entirely after about 4 to 6 weeks. ## yes - please beware this was one of the most horrible experiences of my life...I started contrave - was on it for about a month and started experiencing ringing in my ears...it became so loud that I couldn't even hear...I immediate...

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Contrave - restarting and side effects

I've been taking Contrave for about 2 1/2 months. During week 6 or so I was hospitalized with a severe UTI and kidney infection (4 days). The hospital wouldn't give me Contrave during my stay but I resumed when I got home by taking 1 pill a day for a week, then back to the normal doesage of 4/day. I am not noticing any benefits from the Contrave now. 1. I'm wondering if the UTI was a side effect of the Contrave (it's listed as a possible side effect) and 2. Why am I not having any of the benefits? How do I get back to losing? ## Hello Kim, Sorry to hear about your severe UTI but I'm glad to hear that you're doing better now. I have been browsing the Contrave official website for a few minutes and I noticed that I don't see UTI listed as a potential side effec...

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Is it worth it to continue?

I have been taking this pill now for 2 weeks. I lost the 3 lbs the 1st week. Since then I have gained like 6lbs. However, I can tell that it's curbing my appetite, but no more weight loss. I'm trying to decide if I continue. I'm totally sleep deprived and constipated to the max degree...Is it worth it to continue? ## Hello Meme, I would like to help you but I need some information to go off of. What medication are you taking and was it prescribed to you? Just some information that may help you. Eating less food does not necessarily mean that you will lose weight. The only way to lose weight is to burn more calories than you are consuming in a day, so no matter how low your intake is you could theoretically still gain weight if you were to burn less energy. If you don't f...

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Possible Dosages for this and Related Drugs:

Bupropion Hydrochloride + Naltrexone Hydrochloride
  • Tablet, Extended Release: 8mg + 90mg, 90mg + 8mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Contrave: (2 results)

Sorted by National Drug Code
  • 50090-2868 Contrave Oral Tablet, Film Coated, Extended Release by A-s Medication Solutions
  • 64764-890 Contrave Oral Tablet, Film Coated, Extended Release by Takeda Pharmaceuticals America, Inc.

Drugs with one or more similar ingredients: (5 results)

Related Contrave Topics:

contrave and sleepiness
I started contrave 4 days ago, today being my 5th dose. every day, i take the pill about 8am and by 9:30-10am I am so sl... 75 replies
Contrave vs Belviq
I was on free 2 weeks of Belviq followed by 1 mo out of pocket Belviq. Lost and felt good with NO side effects at all. T... 73 replies
Contrave and Suboxone
I started today with my first dose of contrave, 1 pill in the AM. I also take suboxone 8mg (4 1 time a day). My doctor s... 63 replies
Contrave and alcohol consumption
I have filled my prescription of Contrive but have not yet started taking it. I read all the possible side effects and a... 52 replies
Contrave and High Fat Foods
I ate a high fat meal (stuffed baked potato) tonight and am wondering when it is safe to take my evening dose of Contrav... 46 replies
Contrave / ringing in ears
Has anyone suffered from ringing in ears from Contrave? I'm going insane :(. but losing weight :) ## Hello, Jojo! Ho... 36 replies
Contrave and Vomiting
I have been on Contrave for 3 months. I have battled nausea all along, hoping it would go away. I've lost 15 pounds.... 22 replies
Contrave and appetite control
I'm currently on week 3 of Contrave (2 pills in the AM/1 in the PM). When should I possibly be noticing a decrease i... 20 replies
contrave and cymbalta
On day two of Contrave but also on 30mg of cymbalta. My doctor didn't seem to have any worries on both together. Has... 13 replies
contrave not working anymore
I took Contrave and lost 52 pounds in 10 months, which has put me back to my ideal body weight. The problem is that it h... 12 replies






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