Active Ingredient(s): Bupropion Hydrochloride + Naltrexone Hydrochloride
FDA Approved: * September 10, 2014
Category: Diet / Weight Loss

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Contrave Overview

Bupropion/naltrexone is a combination drug used for weight loss in those that are either obese or overweight with some weight-related illnesses.[1][2] It combines low doses of bupropion and naltrexone. Both drugs have individually shown some evidence of effectiveness in weight loss, and the combination has been shown to have some synergistic effects on weight.[3] In September 2014, a sustained release formulation of the drug was approved for marketing in the United States under the brand name...

Read more Contrave Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Contrave Forums: RSS Feed

How long will it take to lose 20 pounds on Contrave?
2 Replies RSS
Hello. I am just on day 2 of Contrave and was wondering, as I only really need to lose 20 pounds, is this the right drug for me? I don't mind if it takes a few months. I just need to stop sugar and carb cravings that I have had which added these 20 to my 5'2" small frame. At my height, that's a whole new wardrobe that I don't want to buy. ## There is no set schedule anyone can give you, since we are all different, plus it depends on your diet and activity levels. The FDA warns that it may cause side effects, such as nausea, dizziness, headache, nervousness, insomnia, and anorexia. How are you doing on it? Can anyone else that's taken this medication chime in? I'm currently converting most of wardrobe to Lularoe clothing, not because I need to, just because I ...
Updated 8 minutes ago.
Not Working Anymore
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I have been on Contrave for 7 months. It started out great. I've lost 70 pounds and it controlled my appetite well. Over the past month, I have noticed it has stopped controlling my eating habits and I am starting to crave and eat like I used to. Is it possible that your body becomes immune to Contrave?
Updated 6 hours ago.
Itching from Contrave
36 Replies RSS
I have been taking Contrave for three weeks and have developed itching on the insides of my hands and the bottoms of my feet. Has anyone else experienced this? ## Hello, Arlie! How are you? Do you have a rash, or just the itching? Contrave has been known to cause a rash as a side effect, as listed by the FDA. You may also experience nausea, dizziness, headache and insomnia. Are you on any other medications? The itching could be due to a circulation problem. ## No rash. No other meds. Nothing new besides the Contrave. ## There's a chance that it's affecting your circulation, which can cause itching. Have you had it checked out by your doctor, yet? Has it improved, at all? ## I have cut the dosage in half (one pill in the morning and one in the evening) and no longer have the itch...
Updated 2 days ago.
Contrave and alcohol consumption
40 Replies RSS
I have filled my prescription of Contrive but have not yet started taking it. I read all the possible side effects and am weary about taking in and wanting to continue to socially drink (glass of wine, socially drink on weekends) ## @pnj, According to's drug interaction checker, there ARE potentially dangerous interactions between Contrave and Alcohol. These statements go on to note the following: Consuming alcohol with Bupropion (one of the active ingredients in Contrave) may lead to an increased risk of seizures, decreased tolerance to alcohol, muscle spasms, confusion, and changes in cognitive awareness. For those reasons mentioned above, I would not encourage anyone to take the two together or even within the same day. Hope this helps! ## OK, I read the notice about alco...
Updated 3 days ago.
Contrave and suboxone
35 Replies RSS
I started today with my first dose of contrave, 1 pill in the AM. I also take suboxone 8mg (4 1 time a day). My doctor stated that the interaction of the two should be minimal..yeah NO! I got diarrhea, hot flashes, chills, body aches, and pretty much every withdrawal symptom known to man. I now dont want to take the contrave because I am not ready to stop the suboxone. Should I just stop the contrave and continue the sub? Or how should I go about this? ## Hello, Kiat! How are you? I'm very sorry about what happened. Yes, the Naltrexone in Contrave can cause you to go into withdrawal from any opiate, as listed by the FDA, and you were doubling it up with the Naloxone in the Suboxone that does that same thing. As to how to continue, it usually takes about 3 days, before you can safely...
Updated 3 days ago.
Side effects of Contrave
9 Replies RSS
I'm on my third day. Today I have a severe headache. But my question is this, has anyone had bad diarrhea? I get cramps, then bam. But I was feeling better by night. Today is the worst. Should I continue or stop? ## Hello, Shercon! How are you doing? I'm very sorry about the way you're feeling. Those can be normal side effects of Contrave and it may take about a month for them to wear off, as your body gets used to the medication. Other side effects, as listed by the FDA, may possibly include dry mouth, dizziness and nausea. Have you consulted your doctor? Unless they feel there is some reason to be concerned, you should most likely continue taking it. ## Verwon -- are you taking Contrave? ## I'm on Contrave and the stomach discomfort wore off, very mild headache left to...
Updated 3 days ago.
Anyone prescribed, Contrave as well as Phentermine & Belviq at once?
14 Replies RSS
I began taking Phetermine in October of '14, weighing in at 272 big ones! Yikes! I had weight loss--but in December my doctor suggested we pair the Phen with Contrave. He said it would help in the evening when I usually like my snacks. My weight loss was minimal but still there. By Feb. '15, I'm down 55lbs, but again weight loss was moving slower. So my doctor wants me to add Belviq. I've been taking all three and so far no major side effects. Just thirsty for water. I feel like contrave is supposed to be this miracle drug, but I don't feel like it does anything. Am I the only one being prescribed all these at the same time? Side note, I just has full blood work completed to make sure none of my organs are shutting down from this. Since day 1, I've eaten better a...
Updated 5 days ago.
Contrave and Effexor
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My doctor put me on Effexor for hot flashes and other symptoms associated with menopause. Can this be taken with Contrave?
Updated 5 days ago.
Contrave Evening Dose
7 Replies RSS
I'm starting my 2nd week on Contrave tomorrow and the prescription says to take 1 in the morning and one in the evening. If I take the morning dose around 7 a.m., what time should I take the evening dose? I haven't been able to find any information on how far apart the doses should be taken. Thanks. ## Hello, Bobbye! How are you? It's usually taken at meal times, so with breakfast and dinner, but are supposed to avoid taking it with a very high fat meal. The FDA lists its typical side effects as possibly including nausea, dizziness, headache and dry mouth. Is there anything else I can help with? ## When exactly should I take the medication? Everything I read so far only says with a meal....but does it mean before or after the meal? I was wondering if it made a difference. Th...
Updated 5 days ago.
Contrave and appetite control
12 Replies RSS
I'm currently on week 3 of Contrave (2 pills in the AM/1 in the PM). When should I possibly be noticing a decrease in appetite/cravings? Evenings are the worst for me, and I'm finding absolutely NO decrease in my desire to eat. Am I being too impatient? I was on Phentermine for 4 months, and had lost 30 lbs. I had started to plateau, and that's why my Dr. switched me to Contrave. Since I started with this medication, I've gained 8-10 lbs. because my evening appetite is back. I'm currently on a diet/exercise program where I'm eating typically 1000-1200 calories per day. ## I am having the exact problem if anyone can help answer this question I'm willing to listen. ## Regarding when Contrave starts working, I think the answer is going to be quite different for ...
Updated 6 days ago.

Possible Dosages for this and Related Drugs:

Bupropion Hydrochloride + Naltrexone Hydrochloride
  • Tablet, Extended Release: 8mg + 90mg, 90mg + 8mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Contrave: (2 results)

Sorted by National Drug Code
  • 50090-2868 Contrave Oral Tablet, Film Coated, Extended Release by A-s Medication Solutions
  • 64764-890 Contrave Oral Tablet, Film Coated, Extended Release by Takeda Pharmaceuticals America, Inc.

Drugs with one or more similar ingredients: (5 results)

Possibly related Contrave Topics:

Contrave vs Belviq I was on free 2 weeks of Belviq followed by 1 mo out of pocket Belviq. Lost and felt good with NO side effects at all. T... 71 replies
contrave and sleepiness I started contrave 4 days ago, today being my 5th dose. every day, i take the pill about 8am and by 9:30-10am I am so sl... 54 replies
Contrave and alcohol consumption I have filled my prescription of Contrive but have not yet started taking it. I read all the possible side effects and a... 40 replies
Contrave and suboxone I started today with my first dose of contrave, 1 pill in the AM. I also take suboxone 8mg (4 1 time a day). My doctor s... 35 replies
Contrave / ringing in ears Has anyone suffered from ringing in ears from Contrave? I'm going insane :(. but losing weight :) ## Hello, Jojo! Ho... 24 replies
Contrave and High Fat Foods I ate a high fat meal (stuffed baked potato) tonight and am wondering when it is safe to take my evening dose of Contrav... 21 replies
Contrave and appetite control I'm currently on week 3 of Contrave (2 pills in the AM/1 in the PM). When should I possibly be noticing a decrease i... 12 replies
contrave and cymbalta On day two of Contrave but also on 30mg of cymbalta. My doctor didn't seem to have any worries on both together. Has... 10 replies
Contrave and Vomiting I have been on Contrave for 3 months. I have battled nausea all along, hoping it would go away. I've lost 15 pounds.... 10 replies
Contrave Evening Dose I'm starting my 2nd week on Contrave tomorrow and the prescription says to take 1 in the morning and one in the even... 7 replies

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