Active Ingredient(s):Nelarabine FDA Approved: * October 28, 2005 Pharm Company: *SMITHKLINE BEECHAM Category:Cancer
Nelarabine, sold under the brand names Arranon (US) and Atriance (EU), is a chemotherapy medication used for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL).
Nelarabine is a prodrug of arabinosylguanine nucleotide triphosphate (araGTP), a type of purine nucleoside analog, which causes inhibition of DNA synthesis and cytotoxicity. Pre-clinical studies suggest that T-cells are particularly sensitive to nelarabine. In Oc...
* May have multiple approval dates, manufacturers, or labelers.