Active Ingredient(s):Everolimus FDA Approved: * March 30, 2009 Pharm Company: *NOVARTIS PHARMS Category:Cancer
Everolimus, sold under the brand name Afinitor among others, is a medication used as an immunosuppressant to prevent rejection of organ transplants and as a targeted therapy in the treatment of renal cell cancer and other tumours.
It is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR).
It is marketed by Novartis under the trade names Zortress (US)...
* May have multiple approval dates, manufacturers, or labelers. 3 Discussions