Acetohydroxamic Acid

Category: Urinary System

Acetohydroxamic acid (also known as AHA or by the trade name Lithostat) is a drug that is a potent and irreversible enzyme inhibitor of the urease enzyme in various bacteria and plants; it is usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by urease;[1] it thus disrupts the bacteria's metabolism through competitive inhibition. Orphan drug In 1983 the US Food and Drug Administration approved acetohydroxamic acid (AHA) as an ... [wikipedia]

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