Cresp (Vials) is a low-cost version of long-acting anemia drug darbepoetin alfa (Aranesp).
Crep Vials Cost USD 175$ for 100 mcg.
Darbepoetin is a much longer-acting version of epoetin alfa which is used in the treatment of severe anaemia in chronic kidney conditions and cancer.
Cresp is the worldâ€™s first generic version of darbepoetin alpha in the world and the only darbepoetin alfa in India (manufactured by Dr Reddyâ€™s)
Drug Controller general of India has given approval for Cresp for the treatment of anaemia due to chronic kidney disease and anaemia due to chemotherapy.
Darbepoetin alfa is a modified version of epoetin alfa (rHuEPO), which is engineered to have a longer half life, increasing (up to 3 times) the time it remains in the blood. This results in a reduced frequency of doses, providing a simpler and more convenient treatment option for patients and physicians as compared to treatment of anaemia with epoetin which is the current standard of care in India.
Cresp is available in both vials and prefilled syringes (PFS), â€œCresp will offer patients an improved treatment regimen at affordable pricing,â€ The launch of Cresp by Dr Reddyâ€™s is a significant step in redefining the treatment of anaemia.
Reditux, launched three years ago, was the first, and still the only biosimilar monoclonal antibody in the world. Cresp represents another important first as the only biosimilar Darbepoetin alfa in the world. Globally, darbepoetin is marketed by Amgen under the trade name Aranesp. Darbepoetin was approved in September 2001 by the Food and Drug Administration for treatment of anemia in patients with chronic renal failure.
Darbepoetin alfa injection causes the bone marrow to produce red blood cells. If the body does not produce enough red blood cells, severe anemia can occur. This often occurs in people with chronic kidney failure whose kidneys are not working properly. Darbepoetin may be used for patients on kidney dialysis or for those not on dialysis. Anemia can also occur in people who are receiving chemotherapy to treat cancer
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