Efudex Forums

Recently active Efudex forums and community discussion threads. Post your question or story about Efudex and connect with others who have experience with the same medications. No registration is required and your identity remains anonymous.

Popular Threads

Recently Active Discussions

of 2    Next Page     New Thread    RSS Feed
Efudex with Dovonex

Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50% Dovonex (vitamin D) and it was very fast and easy. Four days of application of the combo "lit up" my face and 7 days later my face and scalp were virtually back to normal. Minimal pain, like a sunburn, and no scabbing, pus, etc. I was really scared to do the longer treatment after reading blogs and looking at pictures, but the new treatment is a piece of cake. Plus, according to related articles, it actually works better. A real win-win! "SCOTTSDALE, ARIZ. – A four-day topical combination regimen of 5-fluorouracil (5-FU) and calcipotriene removed almost 90% of facial actinic keratoses – significantly more than with 5-FU monotherapy, in a rando...

Applying efudex to my face and how often to shave

I am applying efudex to my face. I usually shave every 2 days. Should I shave everyday so that my facial hairs do not interfere with spreading the cream on my face?

can i reduce efudex application from twice a day to once

I’m in week 4 of a prescribed 5 week treatment on my chest with Efudex . My skin has all the worst symptoms described in blogs. I felt that my skin was too raw to handle the cream twice a day. I have decided to only apply Efudex once a day for the rest of the treatment (12 days). Will this be a problem for my outcome? ## It would be best to speak with your doctor, before making any changes to your usage regimen. The FDA lists its typical side effects as possibly including skin burning, soreness, hyperpigmentation, photosensitivity, and scarring. Which ones are you experiencing? ## All of them. I had to sleep with a cold pack on the treated skin. Now 1 week after my last application (6 weeks total) Less pain and weeping but possibly weeks away to get back to normal. I have learned ...

Efudex on scalp - side effects on hair?

Has anyone used Efudex on their head? I'm interested in any side effects on hair deterioration or loss. ## Hello Hoody, Reportedly this will be determined by the amount of efudex that you need to apply. If applied topically then the medicine will not be absorbed into the bloodstream and thus will not cause hair loss like other forms of chemotherapy treatment. If it is necessary to apply enough cream that it will absorb into the blood stream then you will start to experience typical symptoms associated with chemotherapy such as nasuea, vomiting, hair loss etc. Below is a link to the source of my information. [1] Efudex Treatment I hope this answers your question. Let me know if you would like to know anything else regarding this medication. ## Thanks so much Kevin. Will be a 14 light...

use of Fluorouracil 5% on your scalp

I read that you should wash the site before application. Are you to wash your hair everyday, twice a day if you apply Fluorouracil 2 x per day? Is it ok to use your regular shampoo. I understand that use of Fluorouracil cream can spread to areas that may not already show signs of precancerous spots. Has anyone noticed this to happen? How far has it spread, entire scalp? Please share any experience you have had with treating scalp.

Headaches with Efudex treatment

I am on Day 30 of Efudex treatment on the top of my nose and a small area on my chest. I stopped the cream on Day 28 as the skin was starting to erode. I've had headaches the past two weeks that won't go away with ibuprofen, Goody's headache powders, tylenol... nothing. It's caused me to generally feel like crap. Anyone else have these headaches? ## Headaches are a possible side effect of Effudex, according to FDA reports, other side effects may include skin burning, dizziness, chills, and nasal irritation. How long has it been since you stopped using it, now? Has there been any change? Have you informed your doctor of the problem?

The 3-week Efudex / Fluorouracil nightmare is now unnecessary!!

Harvard Medical recently discovered a new treatment regime for AK. This new four-day Harvard Medical protocol is going to save us all from the Efudex & Fluorouracil nightmare: Adding calcipotriene to 5-FU dramatically reduced AKs I used this 4-day treatment for AK in Dec '18 and it works!! Save yourself from the 3 week fluorouracil nightmare and do this 4-day treatment instead. I made this Youtube video of my experience with this protocol: The treatment resolves actinic keratosis in only 4 days. No longer is the pain and discomfort of the commonly prescribed 3 week Flouracil necessary to clear your skin of these pre-cancerous lesions. Mix 5% Fluoroucil and Calcipotriene 50/50 and apply twice per day for four days. Both of these creams can be purchased through prescription. Your ...

Efudex doesn't have to be a nightmare

I was prescribed Efudix to treat spots on the back of my hands. I have been applying a thin layer daily for 4 weeks. I have had no side effects, no irritation, burning sensations, blistering or pain. The spots have become slightly redder and that's all. Efudix does not have to a nightmare and every case is different. ## That is correct, we are all different, so not everyone will experience side effects while using it. The typical side effects may include skin redness, burning, sun sensitivity, and swelling. Are you still experiencing good results with it? ## Hi. I will touch base with you again early next week. I am meeting the skin doctor on Monday to get their opinion. Still little or no change after 6 weeks. The Pharmacist has suggested twice daily application but I will be guide...

Efudex "Improved Formula"??

I am scheduled to start Efudex Nov. 2 and am apprehensive based on a friend's bad experience and other things I've read. My Dr. said that things have improved dramatically within the last year with a better formula. He said I will use the cream twice daily for 5 days, then he will see me to place a neutralizer on my face, and then I will heal the 2nd week; reducing the experience from a 4 to 2 week timeframe. Has anyone else heard of this or experienced this? ## Hello, Gina! How are you? What type of bad experience did your friend have? As to an improved formula, that might be true, but the active ingredient that could cause any side effects remains the same, so the FDA still lists them as possibly including skin redness, flaking, itching, and peeling. It isn't really a neut...

efudex on forearms and back of hands

I have been using Efudex on my fore arms and the back of my hands for two weeks. Three weeks will be the total time of application. I put the cream on at night and try to sleep. I leave it on overnight and wash it off carefully about noon the next day. How soon after application can I use soap and water on the treated areas? Does it help to wash the Efudex off after an hour? I have been leaving it on for hours. When sleeping should i wear cotton gloves and a long sleeved t shirt? I have done that and now have stopped but I am concerned about accidently getting the cream in my eyes during the night. Thanks for any help with these questions. When I lower my arms, I have a lot of pain, especially when I lower them quickly. Is this normal?

Efudex 5% and Silkis 3

My new dermatologist has prescribed a one-week per month treatment over four months, applying Silkis 3 in the morning and Efudex 5% at bedtime. I have used Efudex before in one spot, with the expected itching and scabs. What happens when I apply these creams all over my face and scalp, which don't have many particular keratosis spots? My job involves working with the public. ## My dermatologist prescribed Efudex and Desonide last week! Beginning tonight... 7 days Efudex and Desonide am and Desonide pm, followed by Desonide twice a day for 3 days, then stop for 3 weeks. Repeat 4 times after that ! ## How did this protocol work for you? Do you react quickly. How soon did the redness go away? I’m using a Efudex and a synthetic D3 derivative gel called Calcipotriol. I mix them 50-...

Treating wound after 12 weeks of Efudex

My wound is on my forearm & is about a 1 1/2” square. The skin is eroded and indented. Was told to use Neosphorin, keep covered & change bandages twice daily. Does this sound like good advice? ## This procedure is often advised for some types of wounds, but it depends on the severity, cause of the wound, and etc. Neosporin has been known to cause some skin reddening, rash, and itching, as side effects, in some people that use it. What has your doctor advised you to do?

Very Sore Lips

I am a new Efudix user (week 3) with solar keratosis patches on my face, 8 of them. I am coping OK though as expected, not feeling pretty at this stage! I've read and re-read patient info. but don't see anything about very swollen and sore lips as being a possible side effect of Efudix cream. My AK patches are down each side of my face, nowhere near my lips. My worst patch is starting to ulcerate/crust, so another fortnight to go at least. I can cope with the discomfort, all except for my lips - any ideas? Hats off to all you guys for your encouragement! ## Have you consulted your doctor? Efudex has been known to cause some generalized reactions, including skin pain, irritation, and sun sensitivity. Are you on any other medications? Are you making sure to stay out of bright sunl...

Allergic reaction?

Used Efudex on back of my hand a year ago with little reaction. Had to use again & this time hand turned into Krakatoa! Scabs & weeping spread beyond immediate application site but understand this can happen. However, also have tiny pin head size blisters among & around the crusting with accompanying itching which I haven’t noted in other experiences on here & wonder if it’s an allergic reaction or part of the “process” & I just need to find something to ease the itching. Any advice really welcome as this time of use is becoming quite scarey ## While those can be normal side effects, it is always best to have your doctor check things out to be sure. Other side effects to Efudex may include skin color changes, swelling, and dryness (the last of...

Efudex-40 (fluorouracil)

Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this crazy? ## Not really. It is listed in the drug monograph that it can be used topically to treat certain cancerous or possibly cancerous conditions. ## Has anyone used it on their lips? Won't it just keep bleeding non-stop? ## Heidi- I've used it on my lips three times. Each time it was an application morning and at bedtime. Though about the second week it gets very sensitive and blister-like lesions appear that means it's working. I applied a product called Acquafor (like Vaseline Jelly) to seal it and protect). The healing takes some time but the outcome is worth it. ## I just used Efudex for 2 weeks on lower lip. from day 7 blistered and ulcerated and wept...

Efudex, Dovonex and Desonide

My husband has been prescribed Efudex for 10 days (morning and evening on his scalp). Also, Dovonex twice daily and pop-Desonide twice daily (as needed). Which cream does he put on first, second...? Thank you.

Efudex treatment effects

I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What should i do? ## Hello, Judy! How are you? Have you informed your doctor, yet? The U.S. FDA does list the dryness/crusting as being possible side effects of using it. It may also cause abdominal pain, headache and mouth sores. How long has your doctor instructed you to use it? ## Medline Plus states "If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil. If you are using fluorouracil to treat basal cell carcinoma, you should continue using it until the...

Efudex 5%

Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swelling or any sign of side effects. Does this mean the spot on my lip is non-cancerous? I was under the impression I was to have swelling and pain, and that this cream kills everything allowing the good cells to regrow. ## have to start the efudex 5% cream once a day on upper and lower lips. I am extremely worried about the pain. Is there anything besides aquafor or Vaseline to he help with pain? ## It contains the active ingredient fluorouracil, which is used to treat areas of skin that have been heavily exposed to the sun, or those that have been tested to have Basal Cell Carcinoma. The FDA lists its typical side effects as possibly including skin redness, irritation,...

Help with pain while using Efudex cream

I am on week 5 of using Efudex just above my baby toe. Really hard to wear shoes so pretty housebound. The pain has been excruciating the last few days. Tried Tylenol, Tylenol 3 and Ibuprofen - and nothing works. Can anyone recommend something? ## It might be best to speak to your doctor to find out what might help you the most, and do so safely. Efudex has been known to cause some pain, redness, and irritation, to the treated area as side effects, along with itching, and darkening of the skin. Has there been any change? Are you on any other medications?

Redness after Efudex treatment

I have used Efudex twice over several years. I wonder what will help the redness that happens after the crust has peeled away? The affected area is upper lip and side of nose. ## Hi Ren, have you finished taking the course of Efudex at this point? Medline Plus says "If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil." It also says that the redness is normal, except in cases of a severe red skin rash (which should be reported as a serious side effect). Would you consider your case severe? As to treating the redness, you may be able to apply an over the counte...


2 pages of forums were found.

Next Page >

Discuss Efudex

No registration needed.
Simply fill out the form below.

Discuss: Efudex

What are the main keywords of your topic?



Required to start a new discussion.

5) Text Verification: *
Prevents SPAM.

Show Verification Text

with the privacy policy (20210315).

This form will be submitted securely
Privacy policy cookies information


Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use and Privacy Policy. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.

Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 29 March 2021.

We are committed to your privacy.

Copyright © 2005-2021 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA