Diovan And Benicar

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Forrest Says:


I have been taking Benicar 20mg for high blood pressure and it was working in combination with two other meds. My drug plan had my doctor change it to Diovan 160mg. Does the Diovan need to be such a large dose compared to the Benicar? Both are angiotensin II receptor meds so do they work the same way?


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David Says:

Hi Forrest,

Even though both of these medications are angiotensin II receptor antagonists and both work by blocking the binding of angiotensin II to the AT1 receptor in many tissues, they still have completely different chemical structures by which the drugs themselves are synthetically constructed.

It's really just this factor along with any other inactive ingredients (binders and fillers) that are put in each tablet, which can determine how each drug is metabolized by your body. In light of this and because everyone is different, your body may agree with one medication over the other, due to how you feel after absorbing the drug or based on whatever side effects present themselves.

I hope this helps explain everything!

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Gmommap Says:
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My husband was on benicar for about a month but he had so much anal pain he couldn't sit, sleep, or even walk... Thought he had developed a hemorhoid but came out negative. Since only change was adding benicar he stopped taking it to see if it helped. It took a couple of weeks, But he started feeling better... Doctor said benicar couldn't have been the cause, so he tried it again. Pain was back in a couple of days, so he stopped it for Good.

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