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contrave and sleepiness

I started contrave 4 days ago, today being my 5th dose. every day, i take the pill about 8am and by 9:30-10am I am so sleepy I can't stand it. Days 1 and 2 I managed to fight it off until about 12-12:30, day 3 until about 1-1:30, and day 4 I fought it off until 3pm. If I take a 1-2 hour nap, I wake up fine, with energy and then cannot get to sleep until about 2am, sometimes 3am. Today is day 5, I'm having that "drunk" feeling and sleepy, but no where near how it has been. It seems this effect is slowly wearing off, but I haven't seen anywhere where this is a common side effect. I know all medications effect everyone differently, so I'm wondering if this is something I should be concerned about, or just another side effect that I will get used to as the weeks go o...

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Contrave and weight gain

I've only been on Contrave for 4 days and I've gained 6 pounds. My legs, feet and stomach are swollen, so I assume it's retention of water? Anyone else had this reaction? ## The FDA does list that as a possible side effect, along with nausea, dizziness, irritability, nervousness, and insomnia. Have you consulted your doctor? That is always the best thing to do to be sure. Such rapid weight gain can also be a sign of other potential risky health issues, such as congestive heart failure. Are you on any other medications? ## I have been drinking a ton of water since I started the meds last week. I would be sure you are drinking a lot. That will help with the fluid retention. ## Hello everyone, I am at the beginning of week 5 and have not really lost any weight. Maybe a pound or...

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Contrave and High Fat Foods

I ate a high fat meal (stuffed baked potato) tonight and am wondering when it is safe to take my evening dose of Contrave. All the warnings say is do not take with a high fat meal. Well, how long do you have to wait? There is no information on that! Has anyone heard? ## Hello, MrsMeck! How are you? Have you tried asking your doctor? Unfortunately, I'm only finding the same thing you are, not to take it with a high fat meal, but no specific time frame. Taking it with a high fat meal creates the risk of seizures. Other typical side effects, as listed by the FDA, may possibly include nausea, dizziness, headache, nervousness and anorexia. Does anyone know more? ## I spoke to a consultant at Takeda today and they recommended that I call my dr. But the problem would be that the doctor wou...

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Buproprion Users

I take Bupropion for depression already and it is the second of the active drugs in Contrave. I was concerned about that but the doctor knew I was on it at the time of prescription. I am only on day 3. I feel a tad less bloated and found I lost a pound already. Day 2 wasn't great - had nausea, but it finally passed. I'm wondering if high fat foods bring on nausea as I had 2 modest size servings of pizza but heavy on the cheese. I think that had something to do with it. I'm a little concerned as I kick up in dosage on Contrave with the Buproprion already in my system but we'll see and I'll update. Curious if anyone else uses Buproprion as well. BTW, yes it does curb smoking tendencies. ## The manufacturer does warn that it shouldn't be taken with other medications...

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Does Contrave make anyone else's hands shake?

I'm on my 4th week (2 pills each am & pm) of Contrave and I find my hands shaking when i'm holding something and my heart rate is way up. Anyone else go through this? Also, is it safe to stop Contrave all at once or should you gradually go down the same as it was started. ## Yes.. I have been on Contrave for about 5 months and I actually had a different symptom…I was having Phantosmia (Phantom Smells) like I smell smoke when there is none. It has been bothersome… but then I also started feeling shaky and even noticed a true tremor in my right ring finger. I started freaking out because I looked all over the Contrave sight and didn't see this as a side effect. If you look up those two symptoms its points to brain tumor or Parkinsons! I went to my Doc who presc...

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Contrave and Restless Leg Syndrome

Has there been any studies or anecdotal information on Contrave and Restless Leg Syndrome? ## Hello Walt, According to the NIH restless leg syndrome is not an adverse reaction that is associated with this drug, however that does not mean that it's impossible for it to be the root cause. According to the report given by the FDA only 3 individuals out of 2,778 reported restless syndrome as a condition they noticed after taking contrave. Are there any other medications that you are taking in addition to the contrave? ## Since taking contrave, my severe rls is much improved!

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Dosage after taking a break from Contrave

I took Contrave for about four months and lost 10 lbs. Decided I would stop and didn't take it for a month. I immediately started craving sweets again and started gaining weight, so I decided to start taking it again. Got a refill today but not sure if I should start over, with the minimum dosage, or go back to the maximum dosage. Or maybe somewhere in between..maybe two a day? I also seemed to develop a bit of a tremor when I was taking the medication and that got better when I stopped. However, I am diabetic and don't want to gain a lot of weight again. ## I would definitely start slow if I restarted at all. The dosage needs to build up in your system or you may be subject to more severe side effects. GLTU. ## @Rick, Ultimately I think it would be best to consult your doctor f...

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Wanting to quit taking Contrave

I need to know how to stop taking contrave. Can I just quit cold turkey or do I wean off? If I wean off how do I do it? ## Hello, Janice! How are you? How long have you been taking it? Why do you want to stop it? The FDA lists Contrave as being used to aid in weight loss and its typical side effects may possibly include nausea, dizziness, nervousness, insomnia and anorexia. Have you consulted your doctor? It does require slow tapering for some people. ## I was looking up how to wean myself off of Contrave and found this comment on here. I've been taking Confrave for about a month or so. I just started the 2 pills in the morning and 2 pills at night dose Sunday (today is Friday). I've felt horrible all week since increasing it. Hot flashes in my face, horrible nausea, glands some...

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Contrave and Suboxone

I started today with my first dose of contrave, 1 pill in the AM. I also take suboxone 8mg (4 1 time a day). My doctor stated that the interaction of the two should be minimal..yeah NO! I got diarrhea, hot flashes, chills, body aches, and pretty much every withdrawal symptom known to man. I now dont want to take the contrave because I am not ready to stop the suboxone. Should I just stop the contrave and continue the sub? Or how should I go about this? ## Hello, Kiat! How are you? I'm very sorry about what happened. Yes, the Naltrexone in Contrave can cause you to go into withdrawal from any opiate, as listed by the FDA, and you were doubling it up with the Naloxone in the Suboxone that does that same thing. As to how to continue, it usually takes about 3 days, before you can safely...

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Contrave and Celexa

I just filled my prescription and will be starting tomorrow. I'm excited but nervous as I'm on Celexa and I've read that there is a possibility of major side effects. Has anyone else experienced anything? ## The Bupropion in the Contrave can increase the effect of Celexa, so you do need to be careful of that and your doctor may need to adjust your dosage of it. The FDA lists the typical side effects as possibly including nausea, dizziness, headache, insomnia, nervousness and anorexia. Is there anything else I can help with? ## I'm taking contrave and Celexa. I have been on for 2 months. My last period was very very light and this month not at all. I took a pregnancy test and it was negative. I use Nuva ring and usually start as soon as I take it out. Could this combo of ...

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contrave not working anymore

I took Contrave and lost 52 pounds in 10 months, which has put me back to my ideal body weight. The problem is that it has not been working after that 10 months. I don’t have any side effects, but have a ridiculous appetite now. Almost to the point of wanting to binge eat. Anybody else been on it a while and have it stop working? I’ve gained almost 10 pounds back in the last few months. I’m not sure whether to ask my doctor about stopping it, but I’m afraid my appetite will be even worse. Anybody? ## I had the same problem. I was starving hungry and wanted to eat and eat. Weirdest thing was that I felt constantly hungry even after a week? ## You are not the only people who have experienced such issues. Most people who have tried it have reported eventually hittin...

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Stopping Contrave prior to surgery? How long???

I've been on Contrave for 6 months with some slight success. I've lost about 6 lbs, but I also have not gained any weight, which is at least a step in the right direction. I don't follow all the rules and don't exercise enough. I was initially scheduled to have ENT surgery for a severe sinus infection in 2 days (Wednesday). Surgery has now been moved to 8 days (following Tuesday). My GP told me today that I should off Contrave for 2 weeks prior to surgery because of the naltrexone, because it might interfere with anesthesia. I've looked online and cannot find any mention this. She also told be that because the naltrexone dose (8mg) is so I need to check with the anesthesiologist to be sure. I called the surgeon's office and his nurse called the anesthesiologist w...

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Contrave stopped working week 4

I am finishing up my fourth week on contrave. The first two weeks were pretty brutal with all of the terrible side effects. But my appetite was definitely diminished and I did not have the urge to binge eat. Now that I am on week four most of the side effects are gone but I also don't feel like contrave is working at all. My appetite is almost back to normal, I think about food all the time. I'm pretty disappointed. Has anyone else experienced this? ## Yes, most people do report experiencing a period of time where it seems to stop working, for a brief period, but then starts again, after a few weeks. (This is going by user reports as posted online.) The FDA lists its typical side effects as possibly including nausea, dizziness, nervousness, headache, and insomnia. How are you do...

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Contrave and smelly urine

OMGOSH... I can not believe I am asking this, but.... I am on month 4 of Contrave and my urine has an odor. I have looked at the side effects and I do not see that as one of them.... Does anyone else have this issue or is it just me? ## Almost any medication can cause such a side effect, according to NIH studies, since you are adding a new chemical to your body. However, if you start experiencing other symptoms, such as pain, burning when urinating, or blood in your urine, please see your doctor, as soon as possible. Are you on any other medications? ## I’m having the same issue. Going to see doctor to make sure it isn’t another problem, but I’m almost positive it’s the Contrave. Started about a month in as well. ## Yes, yes, yes. I am entering my third month on ...

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Contrave and Vomiting

I have been on Contrave for 3 months. I have battled nausea all along, hoping it would go away. I've lost 15 pounds. The pill seems to make everything taste bad. Coffee, spicy food, even just scrambled eggs taste bitter and gritty. I didn't have any other side effect. This past week, the nausea has moved on to vomiting. I've used Tumms and Dramamine as well as a prescription anti nausea med on and off for all three months. I truly feel poisoned. I feel ridiculous that I have used this knowingly for 3 months and endured feeling sick. I've spent a lot of money and feel terrible even a week after stopping the drug. Please don't take this. I feel that fairly soon enough folks will complain enough to take it off of the market. ## I dont feel that it should be taken off th...

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Killer Headaches

I'm on Contrave almost 3 mos and lost 29 lbs...that's the great part, but lately I am getting the worst headaches, usually over one eye . Lately I've been getting 3 headaches a week and all I could do is lay in bed. Sometimes ice on my head feels better or even the pressure from the pillow being on my head to block out the light helps. I went to my prescribing doctor and she said headaches are a side effect. Other than a headaches my only other side effect is dry mouth. My doctor said the headache should go away as this does happen to a few patients on this meds. Advil migraine doesn't seem to help so I really don't know what else I could take with contrave. If I wasn't on contrave this kind of headache would definitely be gone with a Vicodin! But I know I cannot...

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Contrave Dosage Question

My doctor prescribed to take this as 2 pills 2x per day. Not a ramp up like I read about online - has anyone else done this? I have not started taking the pills yet. ## You really should gradually increase it. It isn't fun gradually, it has to really suck taking it all at once. I would think it could hurt you taking it all straight away. The dr will write the rx for the full amount but either tell the pt to gradually increase or give them a sheet of paper. He gave me a pamphlet from the company that makes it. Ive found this to be common with other medicines that had to be brought up to a full dose over time. You should call and ask your doctor what you should do and tell them about the titration schedule. He may not know about it. I've had to inform my doctors about a lot of thi...

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how long does it take to get contrave out of your system

I need to reduce my intake of Contrave because of side affects. I'm cutting back from 4 pills to 3. How long does it take for Contrave to reduce in my system so that I don't have the severe symptoms? ## Hello, Penni! How are you feeling? Has there been any improvement, yet? What side effects have you been experiencing? When it comes to this medication, it depends on which ingredient is causing the symptoms. The Naltrexone in it only takes about a day, but the Bupropion may take about a week, based on the FDA listed half-lives. ## I saw my doctor yesterday. We have reduced my dosage to 2 pills a day to see if that helps. If not than next week I'll go down to 1 a day. My worst symptoms out of several are hot flashes & nausea. ## I've only been taking contrave for a wee...

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contrave and cymbalta

On day two of Contrave but also on 30mg of cymbalta. My doctor didn't seem to have any worries on both together. Has anyone been on both. I actually skipped my cymbalta for last nights dose because I want off of cymbalta. I have been on 30mg since last November. Any personal experiences?? ## Hello, Erica! How are you? They can increase the toxicity of each other, as well as increasing the risk of seizures, when they are combined, according to the FDA. Thus, they should not normally be prescribed together and it is advised that this only be done as a last resort, when someone is out of other options. Is there anything else I can help with? ## I am wondering the same thing. I am also on cymbalta fornthe past month and a half and now i started contrave a week ago. Everything i read say...

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Taking contrave a second time around

I recently took contrave for a year and had wonderful success! I had all the horrible side effects in the beginning and wanted to quit. I talked to my Dr and he lowered my dose and the intolerable side effects went away! I originally lost 65lbs now after stopping it, I've gained back 30 lbs. After a while though I reached a plateau and it stopped working my appetite came back and I started to gain. I've been off contrave for two months and was wondering if I restarted taking it would it begin to work once more? I guess my question is how long do I have to be off of it for it to be out of my system so that I can start fresh again? ## Most people do report hitting a plateau point, after being on it for awhile, and it usually takes a few months for it to start working, again. I...

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