Itchy Skin
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I've been taking simvastatin for about 4 months and have had a really bad itchy skin reaction, but nothing is relieving it. I do not see this posted as a side effect. Not using grapefruit juice, what else might it be interacting with to cause this great discomfort?

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49

I got my wife Benadryl tabs to see if the work will let you know.

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48

I started simvastatin and after just a few weeks I started to get itchy all over. I would say the itching is head to toe. My eyes and throat even itch. I have allergies and sometimes my face itches and I would say that the all over itching feels similar after taking the simvastatin.

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47

I have been taking Lipitor 10 mg for about 10 years. In early August my pcp (who is a cardiologist) changed my dose to 40 mg daily. I developed a generalized itch (no rash) and did the usual process of elimination to determine the cause. Benadryl was minimally helpful. After about 2 weeks of this misery I contacted my pcp and Phenergan was ordered. Another 2 weeks, and an office visit- suggested xanax. It makes you dopey, but no relief. After multiple attempts at discussion, I stopped the Lipitor (2 days so far). I was surprised to see how many people had very similar stories. This itch is awful. All of my blood work in mid-August was normal. I would appreciate any feedback. How long after the Lipitor was stopped did the itch go away?

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46

Re: Texas Red (# 1) Expand Referenced Message

Yes I've been taking it for a long while but all of a sudden I began itching and I always take it in the evening. I eliminated everything else . First thought it was the juice I took the med with . Well I eliminated that then after no itching I thought it was that but on taking my med it returned. I know it's the simastatin 40 MG.

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45

I agree with you about the medicine Statin. I am a 61 year old female. I have been taking simvastatin for like 20 years now and I have so many problems. PLEASE read the side effects. I have every single side effect. Please stop the simvastatin. I feel like things are crawling on me. I feel things under my skin. I'll look to reach for it and it's not there. Sometimes it feels like ice or water is on my skin but when I touch it, it's as dry as ever. Very scary. My muscles are sore, my legs tingle, I can not remember a lot of stuff family members ask, "girl what is going on with you you don't remember that?" It saddens my heart for me not to remember beautiful memories. NOW, I have a lump on my collarbone and these doctors don't understand why? They are running several test. The lump is hard. The lump does not hurt but the area does from my head to toe. I have to have a colonoscopy to have my thyroid checked and a few other tests. I am fine until the certain part of the day. 7/22/2017

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44

Was on a statin years ago. Assumed I had allergies to perfumed laundry detergent. Tried fragrance free stuff as the itchiness was just always in my trunk stomach area. and sides. VERY bothersome. Doc said my cholesterol wasnt good enough, he doubled my meds (this was generic lipitor). Days later I broke out in boils on my ears. Ceased taking this, DAYS later itch gone that I had had for YEARS. Doctor did not support my decision, didn't believe me, said I NEEDED a statin, nothing else works. Im also diabetic, and I have also found out that statins also raise your blood sugar. It is a vicious cycle. Recently switched doctors, this one is more holistic, prescribed 2000 mg fish oil. OK, I got a great kind, salmon oil, etc. taking over 2000 mg/day. Have blood work done, cholesterol and triglycerides are out of control. I have been off the lipitor for years and feeling wonderful. Old doc put me on Crestor, after 4 weeks, I have itching behind my knees, and on my stomach. It is VERY intense and wakes me up at night. Topicals do not much of anything. Maybe relief for an hour or less. I feel frustrated and that nothing will help me. I hears Zetia isnt a statin? ANyone tried this?

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43

I itched from head to toe. Stopped taking statins for about 6 weeks and the itching finally stopped. My doctor agreed and he still tries to prescribe statins but I refuse them. Taking zetia and Vascepa and no side effects. Just don't take more than two Vascepa at a time or you will feel very light headed.

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42

Yes....Face, scalp and forehead.Been on Simvistatin 2 months.

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41

I've been on Pravastatin, 20 mil for at least 5 years. This is really weird because I've noticed every time I get a new refill (every 6 months) that's when I feel itchy mostly on my arms and legs. Then after few days it goes away. But just recently the itchiness lingers much longer. It itches in my neck, sides of my chin and arms. I tried to put lotion thinking its due to dry skin but it didn't work. So I googled it and found that one of the effects of the statin is an itchy skin.

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40

crestor causing extreme intense itching. do all statins cause itching?

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39

I started simvastatin about 3 weeks ago and have had unbearably itchy arms over the last couple of weeks. I haven't changed anything else so, after reading all these posts I'm convinced it must be the statins that are the culprit. And it really feels like things crawling under my skin, waking me up at night. It's making me feel really quite miserable! Does anyone have an alternative to statins for reducing cholesterol? I've been advised to try Amla supplements (indian gooseberry) so may give it a go and see what my next blood test shows because I can't live with this constant itching :-(

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38

On statin drug for years. 6 months ago started having an itch, no rash, on my chest. Itch has progressed and now is is more frequent, more intense and over a larger area.Ran out of statin medication a month ago and while waiting for the mail delivery of new script the itch was much improved. Can statin's cause itch? Is it possible the itch would occur after years of statin use?

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37

I have been taking Atorvastatin for 3 months I have the Itchy Rash on my upper chest and neck going up into my hair also my lower arms it was so bad I had to have an ice pack on my neck to get any relief at all.I went back to my doctor who said it was a light reaction rash and gave me cream which was no help.Going to stop taking them to see if itching stops will go back to my doctor.

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36

I went on simvastatin for two weeks and developed a rash and itching on my arms and hands. I thought it was from flea or gnat bites but my house is pest-free. I'm convinced the rash was statin-caused and have quit them. The itch and rash have also diminished in the two days since I quit them. My total chol. is 181; hdl 32 and ldl fairly low w trigs so I don't think I need to be on statins at all, despite what my pcp thinks. (Docs get financial incentives for pushing pills on us, you know.)
Forget it. No statins for me anymore,

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35

I am another Simvastatin user who has been putting up with this terrible itching for several years, ever since I started taking it. My itching is very much like that described by others, feels like tiny invisible bugs crawling and burrowing in your skin. I get this frequently on my hands, fingers, lower arms, armpits, back, belly, on my neck behind my ears, scalp, groin, and on the tops of my feet. If if scratch it at all red whelps swell up, almost like poison ivy.

I've stopped taking it for a couple of days now and it seems to have diminished slightly, but I am going to stay off of it and see if it goes away completely. I have another checkup in 6 months and want to see if this drug even reduces my cholesterol, as my levels on it have been good, but my liver levels have also been elevated, so it may be damaging my liver as well. I don't plan to take it again.

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34

I WAS ON STATINS AND HAD A BAD ITCH IN MY BACK AND A RARE CANCAER GREW WERE THE ITCH WAS IT WAS A SOFT TISHUE SARCOMER HIGH GRADE

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33

I was on statins and had a itch for five years and a rare cancer grew were the itch was had a1.5kg tumer removed

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32

I was on statins they gave me accute mussle wastage also never had a heart problem in my life and the mytrol vavle in my heart collapsed after being on them for about a month I have an uncontolable itch in my right side back near the shoulder blade I had the wife scratch it but she used to say there was nothink there I had my heart done but was having trouble walking all my joints were seizing up I gave up the statins and within weeks was getting mobile again the itch was still there and a lump started to grow were the itch was first the lump was about the size of a grape but was growing went to the doctors was told it was a fatty lypoma leave it I said no I want a second opinion three months on fianaly got an oppintment with the local hospital almost 5 months on by this time it was the size of a duck egg again told to leave it I said I wanted it out first went to the doctors end ofJune had byopsey in November told I needed major opp has it was a rare high grade cancer and i was operated on 18th Dec they took out a 1.point 2 klg high grade sarcomer right at the spot were the itching started also had 6 weeks radio theroppy I was told not to take statins ever again and they would take six months to leave my body it is now five years on

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31

Yes I have exactly the same problem on my forehead

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30

Been on Simvastatin for 3 weeks and started with the itch on my legs above my knees 4 days ago. First 2 weeks I was using the tablets from the hospital pharmacy and this last week I have taken some from a local pharmacy. Dr said she hadn't heard of this as a side-effect, however has told me to stop taking the tablets for a few days to see if it stops. Now after reading the comments I wonder if a few days is enough. My over-all cholesterol is not really high so I am tempted to stop the statins. I am also on amlodipine and clopidogrel so I wonder if the Simvastatin is reacting with them.

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