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 Sibrafiban
Sibrafiban (Ro 48-3657, proposed brand name Xubix) is the double prodrug of Ro-44-3888, which is a platelet aggregation inhibitor. It was being developed for secondary prevention of arterial thrombosis following unstable angina pectoris and acute myocardial infarction (MI). On August 6, 1999, Hoffmann-La Roche announced that the preliminary results from Phase III clinical trials had not shown that sibrafiban was better than aspirin in preventing recurrent ischemic events in patients suffering...
 Sibutramine
Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which is no longer marketed. Until 2010, it was marketed and prescribed as an adjunct in the treatment of obesity along with diet and exercise. It has been associated with increased cardiovascular events and strokes and has been withdrawn from the market in several countries and regions including Australia,[1] Canada,[2] China,[3] the European Union,[4] Hong Kong,[5] India,[6] Mexico, New Zealand,...
 Sigmart Nicorandil
Nicorandil is a vasodilatory drug used to treat angina. It is marketed under the trade names Ikorel (in the United Kingdom, Australia and most of Europe), Angedil (in Romania, Poland), Dancor (in Switzerland), Nikoran,PCA (in India), Aprior (in the Philippines), Nitorubin (in Japan), and Sigmart (in Japan, South Korea and Taiwan). Nicorandil is not available in the United States. Angina is chest pain that results from episodes of transient myocardial ischemia. This can be caused by diseases s...
 Signifor Pasireotide Diaspartate
Pasireotide (SOM230, trade name Signifor[2]) is an orphan drug approved in the United States[3] and Europe[4] for the treatment of Cushing's disease in patients who fail or are ineligible for surgical therapy.[5][6] It was developed by Novartis. Pasireotide is a somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs. Pasireotide was approved for Cushing's disease by the EMEA in October 2009[7] and by the FDA in December 2012.[8]...
 Signifor Lar Pasireotide
Pasireotide (SOM230, trade name Signifor[2]) is an orphan drug approved in the United States[3] and Europe[4] for the treatment of Cushing's disease in patients who fail or are ineligible for surgical therapy.[5][6] It was developed by Novartis. Pasireotide is a somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs. Pasireotide was approved for Cushing's disease by the EMEA in October 2009[7] and by the FDA in December 2012.[8]...
 Sil-Tex Guaifenesin + Phenylephrine
Guaifenesin INN /wafnsn/ or guaiphenesin (former BAN), also glyceryl guaiacolate,[2] is an expectorant drug sold over the counter and usually taken orally to assist the bringing up (expectoration) of phlegm from the airways in acute respiratory tract infections. Contents 1 Medical use 2 Side-effects 3 Mechanism of action 4 History 5 Availability 6 Veterinary use 7 Past Research 8 See also 9 References 10 External links Medical use Guaifenesin is used to control cough and is someti...
 Sildaflo Silver Sulfadiazine
Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection.[1] Tentative evidence has found other antibiotics to be more effective and therefore it is no longer generally recommended.[2][3] Common side effects include itching and pain at the site of use.[4] Other side effects include low white blood cell levels, allergic reactions, bluish grey discoloration of the skin, red blood cell breakd...
 Sildec DM Drops Carbinoxamine + Dextromethorphan + Pseudoephedrine
Dextromethorphan (DXM or DM) is a drug of the morphinan class with sedative, dissociative, and stimulant properties (at higher doses). It is a cough suppressant in many over-the-counter cold and cough medicines including generic labels and store brands, Benylin DM, Mucinex DM, Camydex-20 tablets, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, TheraFlu, Cheracol D, and others. Dextromethorphan has also found numerous other uses in medicine, ranging from pain relief (as either the prim...
 Sildec-DM Syrup Brompheniramine + Dextromethorphan + Pseudoephedrine
Brompheniramine (Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane), commonly marketed as its salt brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. It is a first-generation antihistamine. Brompheniramine is part of a series of antihistamines including phenirami...
 Sildenafil
Sildenafil, sold as the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension.[3] Its effectiveness for treating sexual dysfunction in women has not been demonstrated.[3] Common side effects include headaches and heartburn, as well as flushed skin. Caution is advised in those who have cardiovascular disease. Rare but serious side effects include prolonged erections, which can lead to damage to the penis, and sudden-onset hearing...
 Silenor Doxepin Hydrochloride
Doxepin, sold under the brand names Sinequan and Silenor among others, is an antidepressant and sleep aid medication used to treat depression and trouble sleeping.[1] It belongs to a class of antidepressants known as the tricyclic antidepressants (TCAs). It is believed to counteract depression by inhibiting the reuptake of serotonin and norepinephrine (via blocking their transporters), thereby increasing the concentrations of these neurotransmitters in the synapse and increasing the activity ...
 Silexin Dextromethorphan + Guaifenesin
Guaifenesin INN /wafnsn/ or guaiphenesin (former BAN), also glyceryl guaiacolate,[2] is an expectorant drug sold over the counter and usually taken orally to assist the bringing up (expectoration) of phlegm from the airways in acute respiratory tract infections. Contents 1 Medical use 2 Side-effects 3 Mechanism of action 4 History 5 Availability 6 Veterinary use 7 Past Research 8 See also 9 References 10 External links Medical use Guaifenesin is used to control cough and is someti...
 Siliq Brodalumab
Brodalumab (US trade name Siliq Europe Kyntheum ) is a human monoclonal antibody designed for the treatment of inflammatory diseases.[1][2] In February 2017 it received US FDA approval to treat moderate to severe psoriasis in people who have not improved with other treatments.[3] Use is linked to an increased risk of suicide.[3] Mechanism of action Brodalumab binds to the interleukin-17 receptor and so prevents interleukin 17 (IL-17) from activating the receptor. (This mechanism is similar ...
 Silodosin
Silodosin (trade names Rapaflo (USA), Silodyx (Europe and South Africa), Rapilif (India), Silodal (India), Sildoo(India) Urief (Japan), Thrupas (South Korea), Urorec (Russia)) is a medication for the symptomatic treatment of benign prostatic hyperplasia. It acts as an α1-adrenoceptor antagonist with high uroselectivity (selectivity for the prostate). Contents 1 History 2 Pharmacology 3 References 4 External links History Silodosin received its first marketing approval in Japa...
 Siltussin DM Dextromethorphan + Guaifenesin
Guaifenesin INN /wafnsn/ or guaiphenesin (former BAN), also glyceryl guaiacolate,[2] is an expectorant drug sold over the counter and usually taken orally to assist the bringing up (expectoration) of phlegm from the airways in acute respiratory tract infections. Contents 1 Medical use 2 Side-effects 3 Mechanism of action 4 History 5 Availability 6 Veterinary use 7 Past Research 8 See also 9 References 10 External links Medical use Guaifenesin is used to control cough and is someti...
 Siltuximab
Siltuximab (INN, trade name Sylvant; also known as CNTO 328, anti-IL-6 chimeric monoclonal antibody or cCLB8) is a chimeric (made from human and mouse proteins) monoclonal antibody. It binds to interleukin-6.[1][2] Siltuximab has been investigated for the treatment of neoplastic diseases:[3] metastatic renal cell cancer,[4] prostate cancer,[5] and Castleman's disease,[6][7] among other types of cancer.[8] It has undergone a phase I clinical trial in patients With B-cell non-Hodgkin's lymphoma...
 Silvadene Silver Sulfadiazine
Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection.[1] Tentative evidence has found other antibiotics to be more effective and therefore it is no longer generally recommended.[2][3] Common side effects include itching and pain at the site of use.[4] Other side effects include low white blood cell levels, allergic reactions, bluish grey discoloration of the skin, red blood cell breakd...
 Silver Nitrate
Silver nitrate is an inorganic compound with chemical formula AgNO 3. This compound is a versatile precursor to many other silver compounds, such as those used in photography. It is far less sensitive to light than the halides. It was once called lunar caustic because silver was called luna by the ancient alchemists, who believed that silver was associated with the moon.[8] In solid silver nitrate, the silver ions are three-coordinated in a trigonal planar arrangement.[5] Contents 1 Di...
 Silver Sulfadiazine
Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection.[1] Tentative evidence has found other antibiotics to be more effective and therefore it is no longer generally recommended.[2][3] Common side effects include itching and pain at the site of use.[4] Other side effects include low white blood cell levels, allergic reactions, bluish grey discoloration of the skin, red blood cell breakd...
 Simbrinza Brinzolamide + Brimonidine Tartrate
Brinzolamide (trade names Azopt, Alcon Laboratories, Befardin,[1] Fardi Medicals,[2] ) is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Contents 1 Chemistry 2 Indications 3 Pharmacodynamics 4 Pharmacokinetics 4.1 Absorption 4.2 Distribution 4.3 Metabolism 4.4 Excretion 5 Cautions 5.1 Side effects 5.2 Precautions 6 Combination with timolol 7 References Chemistry Brinzolamide is a carbonic anhydra...

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