Collagenase

Drug Index

Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a virulence factor, facilitating the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.[1] Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secret...

Is there a substitute for Santyl ointment (a collagenase treatment)to debride wounds? ## Substitute for Santyl ## Are you having some bad reaction to this ointment? The FDA states that it doesn't usually cause adverse reactions, unless someone is allergic to it, in which cases it could cause breathing problems, swelling, skin irritation, and redness. The former means of debridement were much worse, since they involved having to have the wound scrubbed with a very rough brush, and it was quite painful. This is a much better option. Can you please post back with why you are seeking an alternative?

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can i use this ointment for fongus on my hand ## This ointment is usually used to debride chronic skin ulcers and severe burns. That said, it is probably not the best choice to treat a fungal infection, as it is not an antifungal agent and it could make your skin very sensitive, so the fungus could spread and get worse. Have you consulted your doctor?

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When referring to Santly Collagenase ointment what is meant by " and help to facilitate the spread of gas gangrene" ? "Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in pathogenesis of bacteria such as Clostridium. They are an exotoxin (a virulence factor) and help to facilitate the spread of gas gangrene. " ## Hi Robert, Based on my research, I believe that "to facilitate the spread of gas gangrene" means that this product is intended to treat a Gas gangrene infection. The ointment must stop the spread of the infection and kill the bacteria. Gas gangrene is rare in the United States. The condition is most often caused by a bacteria called Clostridium perfringens. However, it also can be cause...

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Collagenase Clostridium Histolyticum-aaes

Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a virulence factor, facilitating the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.[1] Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secret...

Collagenase

Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a virulence factor, facilitating the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.[1] Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secret...

Collagenase Clostridium Histolyticum

Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a virulence factor, facilitating the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.[1] Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secret...

i think that it is local antibiotic ## Iruoxol contains the active ingredients Collagenase and Chloramphenicol, it is actually used as a wound debridement ointment. It helps to clean to wound and slough away dead skin in the event of necrosis. Common side effects may include: wound pain and a burning sensation. Are there any other questions or comments? ## How much post pain and burning is a hint that you may be allergic to this solution?

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What are the current thoughts on the use of accuzyme as a topical debrider for a wound with high bioburden? ## Accuzyme is very very good. it debrides 90% faster than collagenase. you must know when to stop using it. never had apatient who reacted to it. wound closure is way faster. less pain for the patient. will use it anytime over collagenase, which works like a snail. panafil very very very good for fot ulcers.

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I nee information about collagenase santyl ointment 25o unts/g.

where to buy in us? Thanks, Frankie ## Iruxol contains Chloramphenicol and Collagenase and as far as I am aware, this combination isn't available here. Have you tried asking your doctor about helping you find something similar?

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NDC Database

Collagenase Santyl 250 [arb'u]/G Topical Ointment by Healthpoint, Ltd ## Package Codes: 0064-5010-15, 0064-5010-30, 0064-5010-90 ## Active Ingredients: Collagenase Clostridium Histolyticum

NDC Database

Collagenase Santyl 250 [arb'u]/G Topical Ointment by Smith & Nephew, Inc ## Package Codes: 50484-010-15, 50484-010-30, 50484-010-90 ## Active Ingredients: Collagenase Clostridium Histolyticum

NDC Database

Xiaflex Kit by Auxilium Pharmaceuticals, Inc. ## Package Codes: 66887-003-01, 66887-003-02 ## Active Ingredients: Collagenase Clostridium Histolyticum

NDC Database

Kimchi Vitamin (Lactic Acid 30 mg / Ascorbic Acid 180 mg / Thiamine 0.195 mg / Pyridoxine 0.285 mg / Vitamin a 0.675 mg / Alpha-tocopherol 1.875 mg / Folic Acid 0.03 mg / Collagenase 5.625 mg / Riboflavin 0.24 mg / Cholecalciferol 0.375 mg / Niacinamide 0.045 mg) by Tobico ## Markings: 3;hp;x ## Shape: Round ## Color: Pink ## Package Codes: 52102-1001-1