PulmozymeActive Ingredient(s): Dornase Alfa
FDA Approved: * December 30, 1993
Pharm Company: * GENENTECH
Category: Genetic Disorders
Dornase alfa (proprietary name Pulmozyme from Genentech) is a highly purified solution of recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus of cystic fibrosis patients and reduces viscosity in the lungs, promoting improved clearance of secretions. This protein therapeutic agent is produced in Chinese hamster ovary cells. Contents 1 Cystic fibrosis 2 Contraindications 3 Economy 4 Off label use ... [wikipedia]* May have multiple approval dates, manufacturers, or labelers.