Active Ingredient(s): Dornase Alfa
FDA Approved: * December 30, 1993
Pharm Company: * GENENTECH
Category: Genetic Disorders

Dornase alfa (proprietary name Pulmozyme from Genentech) is a highly purified solution of recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus of cystic fibrosis patients and reduces viscosity in the lungs, promoting improved clearance of secretions. This protein therapeutic agent is produced in Chinese hamster ovary cells. Contents 1 Cystic fibrosis 2 Contraindications 3 Economy 4 Off label use ... [wikipedia]

* May have multiple approval dates, manufacturers, or labelers.

Dosage List

Pulmozyme 1 mg/ml Respiratory (Inhalation) Solution
NDC: 50242-100
Genentech, Inc.