Active Ingredient(s):Dantrolene FDA Approved: * January 15, 1974 Pharm Company: *PROCTER AND GAMBLE Category:Muscle Relaxer
Dantrolene sodium, sold under the brand name Dantrium among others, is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. It is the primary drug used for the treatment and prevention of malignant hyperthermia, a rare, life-threatening disorder triggered by ...
* May have multiple approval dates, manufacturers, or labelers. 4 Discussions