Apotex Vs Pliva Trazodone (Page 6)
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My pharmacy just switched manufacturers of my prescription trazodone 50mg. It used to be made by apotex now it is pliva and I am finding that the new pills are having little to no effect and I am starting to suffer discontinuation syndrome. I talked to my pharmacist and doctor and neither one could tell me what was causing this. I was just wondering if there is anyone out there who could shed some light on the subject.

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Thanks for this info. I'm having the exact same issues after pharmacy switched me to Pliva. I'm very sensitive to meds, so your explanation makes a lot of sense.

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No that about covers it. Thank you so much for taking the time to respond.

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Yes, I can.

Under Federal Law, by way of the Hatch Watchman Act of 1984, generics are allowed to differ from their name brand counterparts by as much as plus or minus 20% in the active ingredient.

Many people are not aware of this, including doctors, but the FDA considers this to be a very minor difference that does not affect the therapeutic dosing of medications.

So, the medication you were getting from Apotex may have had the proper amount of the active ingredient Trazodone or perhaps a little more.

Now, the one you are getting from Pliva might have a variation so you are not getting as much as you were, before.

There are some people who are unaffected by such differences, but some people are very sensitive to it.

The only thing you can really do is ask your pharmacy if they can get the one made by Apotex back in for you, or try other pharmacies and see if they have it.

https:/­/­rxchat.com/­wiki/­Trazodone/­

Do you have any questions?

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