Cyclic Ex

Drug Index

Exisulind (tentative trade name Aptosyn) is an antineoplastic agent. It acts by inhibiting the enzyme cyclic guanosine monophosphate phosphodiesterase type 5 (EC 3.1.4.17).[1] It is the sulfone derivative of sulindac, an NSAID. Unlike sulindac, it has known effects on prostaglandin synthesis.[2] It was developed as the potential treatment of several conditions including familial adenomatous polyposis (FAP), precancerous sporadic colonic polyps, cervical dysplas...

Exisulind

Exisulind (tentative trade name Aptosyn) is an antineoplastic agent. It acts by inhibiting the enzyme cyclic guanosine monophosphate phosphodiesterase type 5 (EC 3.1.4.17).[1] It is the sulfone derivative of sulindac, an NSAID. Unlike sulindac, it has known effects on prostaglandin synthesis.[2] It was developed as the potential treatment of several conditions including familial adenomatous polyposis (FAP), precancerous sporadic colonic polyps, cervical dysplas...

Exisulind

Exisulind (tentative trade name Aptosyn) is an antineoplastic agent. It acts by inhibiting the enzyme cyclic guanosine monophosphate phosphodiesterase type 5 (EC 3.1.4.17).[1] It is the sulfone derivative of sulindac, an NSAID. Unlike sulindac, it has known effects on prostaglandin synthesis.[2] It was developed as the potential treatment of several conditions including familial adenomatous polyposis (FAP), precancerous sporadic colonic polyps, cervical dysplas...

I have a CVS (Cyclic Vomiting Syndrome) condion. I experience alot of pain during a cycle. Lyrica works so far. I have experienced no vomiting or nausea during these days. But the side effects are kicking my butt. Dizziness, blurred vision, hyper, I can't stay seated. Staying up very late. Do these side effects subside or go away after the body get adjusated? I'm wired! I'm 43 years old and need to relax. ## I wanted to talk to the person that has CVS! My son has it too, was wondering how they diagnosed you and how often episodes occur. ## I had to see a GI doctor who did a stomach emptying test to rule out gastroparesis, an h. pylori test to rule that out, I had an upper endoscopy years ago otherwise they would do that. They have to just rule out everything else it could be...

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Can taking debendox result in humans developing behavioural disorders that are cyclic in the way they present.my daughter (35yrs old now) can appear quite normal for weeks at a time then she will exhibit borderline pshchotic behaviour then after a few days she will be OK again. ## This contains Pyridoxine and Doxylamine, it isn't used in the U.S., so I have to admit my information on it is limited. Her symptoms, however, sound similar to those of bipolar disorder. Learn more Bipolar disorder details here. Have you consulted a doctor? ## I took debendox when pregnant with my noiw 33 year old daughter. She has problems emotionally but is very bright. I have friends who also took this drug and their children have the same problems. Its almost like they dont grow up and over react to ma...

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I was on Wellbrutrin about 12 years ago and experienced severe nausia for weeks before giving up. A subsequent doctor convinced me to try it again. I has frequent nausea that seemed to ease after a few weeks. Shortly thereafter I experienced cyclical vomiting about every 4-5 weeks. It would last from a few hours to a few days. The doctor said it didn't make sense that Wellbutrin is the cause. I went on that way for a year until I began a clinical trial requiring me to stop Wellbutrin. The vomiting stopped. Months later, after the clinical trial, I restarted Wellbutrin. The vomiting began again within 3 weeks. Has anyone else had a similiar experience? ## Hello, Citygirl! How are you doing? This has been known to happen as a side effect in various medications for some people that try...

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Five years ago I was put on Seroquel during a very anxious, cyclic, bipolar episode due to tremendous stress in my world. What should have been a short term medication (for me), turned into an endless health nightmare. Weight gain, high blood pressure, trouble with making simple sentences in speech, extensive pain from weight I just could not fight, immune system compromised. After a while my anxiety increased and my Dr. increased the Seroquel and just kept pumping it in without listening to me about how physically miserable I was. I changed Dr.'s in November, and he is a Godsend. He put me on Lamactil and I have no side effects from it. However, even though I tapered off the Seroquel, I still suffered a horrible withdrawal that virtually lasted almost 7 weeks. I had a few good days...

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My Dr wants to switch me off of fentanyl because my insurance won't cover it (except under extreme circumstances). I might qualify for those circumstances because I'm allergic to almost every pain med. But we're not sure and I need some other options. What are some of the other long acting opiates that aren't going to cause servere nausea (I have cyclic vomiting syndrome) or are patches like the fentanyl? ## Hi, CD! Sorry about the problems that you're having. However, nausea and vomiting can be a side effect of all opiates, so there's really no way to say which ones may work for you, without causing it. But you may want to talk to your doctor about Butrans and see if your insurance will cover it. It's a transdermal patch, similar to the Fentanyl, that contai...

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52 year old male. Never diagnosed with Covid. For a week I've been extremely fatigued in the morning accompanied with terrible pain, stiffness, and the worst headache pain I've ever had above my right eye. Extremely fatigued until the pain lessens. Happens twice at about 2 am and 10 am, lasts about an hour then slowly the pain is gone. But these actions repeated the following day at 3pm and 6pm. Fine now on the third day. Any ideas? Sound familiar? ## What you are describing sounds very much like a cluster headache. I would certainly go in for a check-up. "Cluster headaches, which occur in cyclical patterns or cluster periods, are one of the most painful types of headache. A cluster headache commonly awakens you in the middle of the night with intense pain in or around one e...

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