MedsChat.com

The People's Medicine Community ®
Drug Index: 

Linzess

Active Ingredient(s): Linaclotide
FDA Approved: August 30, 2012
Pharm Company: FOREST LABS INC
Category: Laxative

Welcome to the Linzess information hub. Scroll down to read supplemental details and discuss this drug.


Linzess Overview

Linaclotide (marketed under the trade name Linzess and Constella) is an peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well.[1] The drug was developed by Ironwood Pharmaceuticals, based in Cambridge...

Read more Linzess Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: http://en.wikipedia.org/wiki/Linaclotide

Recent Linzess Forums: RSS Feed

linzess weight gain
I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Actually, since it usually causes gastrointestinal side effects, including diarrhea, it's usually known to cause the opposite problem of weight loss. You should also be informed that some people develop serve, ongoing diarrhea, so you need to watch out for that and contact your doctor if it happens. Learn more Linzess details here. Is there anything else I can help with? ## I've gained 4 pounds in 3 days since I started taking Linzess. I am on weight watchers so I count points so I know it is not my food intake. I don't usually fluctuate in pounds so I think it's the new meds. I am still taking Miralax but it doesn't seem like either are working. I loo...
Updated 9 minutes ago.
   9  Subscribe to thread 247630
How fast
How fast will the lizness begin to work? I have to go to work and don't want to be running up and down statues all day.
Updated 4 days ago.
   0 
Linzess and strange dreams
Has anyone had any realistic, but odd dreams upon just drifting off to sleep? I just started the 290mcg. Took it 2 days in the AM...nothing, just more bloating but it did help some with the pain. However after reading up some, and considering my work schedule, I thought I should switch to a bedtime dose. WELL...Its working now! But thats ok! I think most of us agree after suffering with being back up for years, hey, whats a lil diarrhea. Problem is, I awoke...well tried to..from a most horrific dream, right upon drifting off. Im usually not a vivid dreamer. Anyone else have this AT ALL? ## Hello, Kris! How are you? Yes, others have reported having this happen, while taking Linzess and it's actually fairly common with most medications, since they often have a direct effect on brain c...
Updated 24 days ago.
   1  Subscribe to thread 267913
Itching or rash while taking Linzess??
Has anyone experienced itching or a rash while taking Linzess? ## Hello, Louloubell! How are you? Yes, those can be side effects of it, though they are very rare. Have had it checked out? It's important to do so to make sure that you aren't having an allergic reaction to it. Other side effects may include heartburn, stomach pain and weakness.
Updated 27 days ago.
   1  Subscribe to thread 267553
linzess help
I have been on linzess fir a week now and no results yet besides bad bloating! Will the bloating go away? How long does is nnormally take to start working? ## How are you feeling? Have your symptoms improved any? It can take several weeks for a medication to reach its full efficacy level in your body and for the side effects to peak and begin to taper off, usually 4 to 6 weeks.
Updated 1 month ago.
   1  Subscribe to thread 265397
different mcg dosage
My doctor gave me samples of Linzess for constipation I though that 290 mcg would work faster, but didn't have any movement, so I tried the 145 mcg and had great results, I'm. Out of the 145 mcg and was wounding if mcg's are different then mg. Is the larger number 290mcg less in strength then the 145mcg? Will I have to take 2 to get the 145 mcg? ## Hello, B J! How are you? And no, it most likely worked because you had those dosages in your system so close together, so they overlapped and combined to help. But to put it in milligrams for you, 145mcgs is 0.145mg and 290mcgs would be 0.290mgs. Is there anything else I can help with?
Updated 4 months ago.
   1  Subscribe to thread 257176
How effective is Linzess
I was diagnosed with impacted bowels today and prescribed 290 mcg of Linzess. My pcp indicated this would get my bowels cleaned out (that I would basically have diarrhea until I am cleaned out) and then I will use it for maintaining good bowel movements. I am wondering how long it will take for it to start working for the cleanout as I need to go back to work but can't until I get this process over. ## Hello, Rena! How are you doing? It has passed the same FDA panel for approval as other medications used for the same or similar conditions. However, the only way to see if it will work for you is by actually trying it. Have you started it, yet?
Updated 5 months ago.
   1  Subscribe to thread 260133

Possible Dosages for this and Related Drugs:

Linaclotide
  • Capsule: 145mcg, 290mcg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Linaclotide or a similar ingredient: (1 result)


Possibly related Linzess Topics:

linzess weight gain I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Act...  9
Linzess and strange dreams Has anyone had any realistic, but odd dreams upon just drifting off to sleep? I just started the 290mcg. Took it 2 days ...  1
linzess help I have been on linzess fir a week now and no results yet besides bad bloating! Will the bloating go away? How long does ...  1
How effective is Linzess I was diagnosed with impacted bowels today and prescribed 290 mcg of Linzess. My pcp indicated this would get my bowels ...  1
Itching or rash while taking Linzess?? Has anyone experienced itching or a rash while taking Linzess? ## Hello, Louloubell! How are you? Yes, those can be side...  1