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Linzess

Active Ingredient(s): Linaclotide
FDA Approved: August 30, 2012
Pharm Company: FOREST LABS INC
Category: Laxative

Welcome to the Linzess information hub. Scroll down to read supplemental details and discuss this drug.


Linzess Overview

Linaclotide (marketed under the trade name Linzess and Constella) is an peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well.[1] The drug was developed by Ironwood Pharmaceuticals, based in Cambridge...

Read more Linzess Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Linaclotide

Recent Linzess Forums: RSS Feed

i am taking linzess at the wrong time will start tomorrow morning when I eat.
I have been taking linzess at night before bed. great stools but very runny and causing burning in that area. Will start taking tomorrow morning after breakfast. I am feeling very bloaty after the 3rd day of taking it.
Updated 4 minutes ago.
   0 
linzess weight loss
how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss, so there is no time frame I can give you for this. It is used to treat symptoms of IBS that are associated with constipation. And while that may cause weight loss, in some instances, it can be dangerous to try to lose weight via giving yourself diarrhea, since it creates the risk of malnourishment and dehydration. Common side effects to this drug may include nausea, dizziness and stomach pain. Was it prescribed for weight loss?
Updated 4 days ago.
   1  Subscribe to thread 275238
How long before Linzess starts to work?
I was prescribed Linzess for my IBS-C. I have been taking Linzess for two days now and very bloated with no bowel movement. From what I had read, it would work rather quickly, but for me that is not the case. I took one 145 mcg the first morning as directed and 2 of the 145 mcg the second morning and still nothing. How long does it usually take before I will start seeing results. I have the urge to have a bowel movement, but nothing is produced. Any advise will be appreciated. ## Hello, CJ! How are you doing? Has it worked, yet? There's really no way to give a time frame, it can vary from person to person. Some people have good luck with it, some don't. One person posted recently that it was only resting in one BM a week for them. Have you consulted your doctor for advice? ## I ...
Updated 17 days ago.
   3  Subscribe to thread 273446
Rumbling in tummy are pretty intense...
I have been on Linzess for 2 months and continue to have constant rumbling in my stomach and intestine if I eat 30 minutes after taking the medication. Sometimes it gets pretty intense and I get sick to my stomach. If I don't eat until lunch, it happens and by then I am nauseous from not eating so it's even worse. Anyone else have this problem and what do you do??? ## Hey tummytrouble, Hope you've managed to tame the rumbling in your stomach. From what I could gather, most of the side effects associated with Linzess are gastrointestinal related... with symptoms ranging from unusual & severe stomach pain, gas, swelling, or pressure in the stomach region. Ref: nlm.nih.gov/medlineplus/druginfo/meds/a613007.html#side-effects If it hasn't gone away yet, I would suggest co...
Updated 25 days ago.
   1  Subscribe to thread 273876
When will the bloating Stop
I have been on Linzess for about a month. I have not had any of the severe side effects mentioned, just the bloating and gas. Does anyone know when those side effects will stop? For the most part the Linzess has worked, I am having regular bowel movements. Since I am so bloated it is hard to eat and therefore I have lost weight that I did not need to loose. Any way any insights would be appreciated! ## Hello, Ag! How are you? I'm sorry about the problem that you're having. Have you looked into taking anything that may ease the gas and bloating? I'm not sure, but you may be able to take Simethicone with it, if your doctor approves it.
Updated 26 days ago.
   1  Subscribe to thread 270314
Itching and rash
I started taking Linzess in early August and around the end of August I broke out with a rash and had severe itching and had to go to a dermatologist. She thinks I had a allergic reaction so I am taking the linzess twice a week. Its not owrking as well as before, but I was miserable for a month with the itching. ## Hello, Lulu! How are you? The problem is that even just taking it twice a week may not be safe, if you are allergic to it, because such reactions tend to get worse with time. Have you consulted an allergist or immunologist? That might be a good idea, in order to get a better idea of what's going on. ## Thanks Verwon, I will talk to my doctor about seeing a allergist. I am allergic to aspirin, penicillin, so I need to check into this. again thanks!
Updated 27 days ago.
   2  Subscribe to thread 273863
Medicationstogether
I take my Linzess in the morning, I love it. I was wondering if I could take the rest of my morning medication at the same time as I take the Linzess? I see no food or drink for 30 minutes but other than that... ## What other medications do you take? I'm sorry, but I'll need more details in order to answer your question. ## Strattera and verapamil are the two main ones that get me going in the morning, also I take vitamin D, magnesium, tramadol, meloxicam, and biotin. I have dysautonomia so the strattera and verapamil are important for get up and go.
Updated 1 month ago.
   2  Subscribe to thread 273415
linzess
Have been taking linzess two weeks only got two bowel movements, should I keep taking it? ## Hello, Brenda! How are you? Is that more or less than usual for you? What has your doctor advised? Do you take any other medications?
Updated 1 month ago.
   1  Subscribe to thread 272985
Linseed
Is it okay to take linzess every other day or when needed dose linzess cause weight gain ## Hello, Bailey! How are you? This medication will work best if you take it exactly as prescribed by your doctor. Side effects may include heartburn, loss of appetite, weakness and diarrhea, so no, it doesn't usually cause weight gain. Is there anything else I can help with?
Updated 1 month ago.
   1  Subscribe to thread 271399
linzess weight gain
I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Actually, since it usually causes gastrointestinal side effects, including diarrhea, it's usually known to cause the opposite problem of weight loss. You should also be informed that some people develop serve, ongoing diarrhea, so you need to watch out for that and contact your doctor if it happens. Learn more Linzess details here. Is there anything else I can help with? ## I've gained 4 pounds in 3 days since I started taking Linzess. I am on weight watchers so I count points so I know it is not my food intake. I don't usually fluctuate in pounds so I think it's the new meds. I am still taking Miralax but it doesn't seem like either are working. I loo...
Updated 2 months ago.
   10  Subscribe to thread 247630

Possible Dosages for this and Related Drugs:

Linaclotide
  • Capsule: 145mcg, 290mcg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Linaclotide or a similar ingredient: (1 result)


Possibly related Linzess Topics:

linzess weight gain I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Act...  10
linzess weight loss how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss,...  1
linzess Have been taking linzess two weeks only got two bowel movements, should I keep taking it? ## Hello, Brenda! How are you?...  1
Linzess and strange dreams Has anyone had any realistic, but odd dreams upon just drifting off to sleep? I just started the 290mcg. Took it 2 days ...  1
linzess help I have been on linzess fir a week now and no results yet besides bad bloating! Will the bloating go away? How long does ...  1
i am taking linzess at the wrong time will start tomorrow morning when I eat. I have been taking linzess at night before bed. great stools but very runny and causing burning in that area. Will start...  0
How long before Linzess starts to work? I was prescribed Linzess for my IBS-C. I have been taking Linzess for two days now and very bloated with no bowel moveme...  3
How effective is Linzess I was diagnosed with impacted bowels today and prescribed 290 mcg of Linzess. My pcp indicated this would get my bowels ...  1
Itching or rash while taking Linzess?? Has anyone experienced itching or a rash while taking Linzess? ## Hello, Louloubell! How are you? Yes, those can be side...  1