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Linzess

Active Ingredient(s): Linaclotide
FDA Approved: August 30, 2012
Pharm Company: FOREST LABS INC
Category: Laxative

Welcome to the Linzess information hub. Scroll down to read supplemental details and discuss this drug.


Linzess Overview

Linaclotide (marketed under the trade name Linzess and Constella) is an experimental peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well.[1] The drug was developed by Ironwood Pharmaceuticals, based...

Read more Linzess Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: http://en.wikipedia.org/wiki/Linaclotide

Recent Linzess Forums: RSS Feed

linzess weight gain
I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Actually, since it usually causes gastrointestinal side effects, including diarrhea, it's usually known to cause the opposite problem of weight loss. You should also be informed that some people develop serve, ongoing diarrhea, so you need to watch out for that and contact your doctor if it happens. Learn more Linzess details here. Is there anything else I can help with? ## I've gained 4 pounds in 3 days since I started taking Linzess. I am on weight watchers so I count points so I know it is not my food intake. I don't usually fluctuate in pounds so I think it's the new meds. I am still taking Miralax but it doesn't seem like either are working. I loo...
Updated 5 minutes ago.
   4  Subscribe to thread 247630
different mcg dosage
My doctor gave me samples of Linzess for constipation I though that 290 mcg would work faster, but didn't have any movement, so I tried the 145 mcg and had great results, I'm. Out of the 145 mcg and was wounding if mcg's are different then mg. Is the larger number 290mcg less in strength then the 145mcg? Will I have to take 2 to get the 145 mcg? ## Hello, B J! How are you? And no, it most likely worked because you had those dosages in your system so close together, so they overlapped and combined to help. But to put it in milligrams for you, 145mcgs is 0.145mg and 290mcgs would be 0.290mgs. Is there anything else I can help with?
Updated 25 days ago.
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How effective is Linzess
I was diagnosed with impacted bowels today and prescribed 290 mcg of Linzess. My pcp indicated this would get my bowels cleaned out (that I would basically have diarrhea until I am cleaned out) and then I will use it for maintaining good bowel movements. I am wondering how long it will take for it to start working for the cleanout as I need to go back to work but can't until I get this process over. ## Hello, Rena! How are you doing? It has passed the same FDA panel for approval as other medications used for the same or similar conditions. However, the only way to see if it will work for you is by actually trying it. Have you started it, yet?
Updated 1 month ago.
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Possible Dosages for this and Related Drugs:

Linaclotide
  • Capsule: 145mcg, 290mcg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Linaclotide or a similar ingredient: (1 result)


Possibly related Linzess Topics:

linzess weight gain I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain? ## Act...  4
How effective is Linzess I was diagnosed with impacted bowels today and prescribed 290 mcg of Linzess. My pcp indicated this would get my bowels ...  1