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Acetaminophen + Butalbital + Caffeine

Butalbital/acetaminophen, sold under the brand name Butapap among others, is a combination medication used to treat tension headaches and migraine headaches.[1][2][3] It contains butalbital, a barbiturate and paracetamol (acetaminophen), an analgesic.[2] Versions also containing caffeine are sold under the brand name Fioricet among others.[4] It is taken by mouth.[2][5] The combinat...

Amiodarone

Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias.[4] This includes ventricular tachycardia (VT), ventricular fibrillation (VF), and wide complex tachycardia, as well as atrial fibrillation and paroxysmal supraventricular tachycardia.[4] Evidence in cardiac arrest, however, is poor.[5] It can be given by mouth, intravenously, or intraosseously.[4] When used by mouth, it...

Bacillus Calmette-Guerin Vaccine, BCG

Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB).[6] It is named after its inventors Albert Calmette and Camille Guérin.[7][8] In countries where tuberculosis or leprosy is common, one dose is recommended in healthy babies as soon after birth as possible.[6] In areas where tuberculosis is not common, only children at high risk are typically immunized, while suspected cas...

Paclitaxel

Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer.[3] This includes ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer.[3] It is administered by intravenous injection.[3] There is also an albumin-bound formulation.[3] Common side effects include hair loss, bone marrow suppressio...

Drug Index

Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer.[3] This includes ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer.[3] It is administered by intravenous injection.[3] There is also an albumin-bound formulation.[3] Common side effects include hair loss, bone marrow suppressio...

Drug Index

Pacritinib, sold under the brand name Vonjo, is an anti-cancer medication used to treat myelofibrosis.[1][2] It is a macrocyclic Janus kinase inhibitor. It mainly inhibits Janus kinase 2 (JAK2) and Fms-like tyrosine kinase 3 (FLT3). Common side effects include diarrhea, low platelet counts, nausea, anemia, and swelling in legs.[2] Contents 1 Medical uses 2 History 3 Society and culture 3.1 Names 4 References 5 External links Medical us...

Enfortumab Vedotin-ejfv

Enfortumab vedotin,[2] sold under the brand name Padcev, is an antibody-drug conjugate[3] designed for the treatment of cancer expressing Nectin-4.[4] Enfortumab refers to the monoclonal antibody part, and vedotin refers to the payload drug (MMAE) and the linker. The most common side effects are fatigue, peripheral neuropathy (nerve damage resulting in tingling or numbness), decreased appetite, rash, alopecia (hair loss), nausea, altered taste, ...

Drug Index

Padimate O is an organic compound related to the water-soluble compound PABA (4-aminobenzoic acid) that is used as an ingredient in some sunscreens. This yellowish water-insoluble oily liquid is an ester formed by the condensation of 2-ethylhexanol with dimethylaminobenzoic acid. Other names for padimate O include 2-ethylhexyl 4-dimethylaminobenzoate, Escalol 507, octyldimethyl PABA, and OD-PABA. Photobiology Padimate O absorbs ultraviolet rays, thereby preventing direct DNA damage by UV...

Drug Index

Pafolacianine, sold under the brand name Cytalux, is an optical imaging agent.[1][2][3][4] The most common side effects of pafolacianine include infusion-related reactions, including nausea, vomiting, abdominal pain, flushing, dyspepsia, chest discomfort, itching and hypersensitivity.[2][3] It was approved for medical use in the United States in November 2021.[2][5] ...

Drug Category

Paget's disease of bone is a chronic disorder that can result in enlarged and misshapen bones. The excessive breakdown and formation of bone tissue causes affected bone to weaken, resulting in pain, misshapen bones, fractures, and arthritis in the joints near the affected bones. Paget's disease typically is localized, affecting just one or a few bones, as opposed to osteoporosis, for example, which usually affects all the bones in the body. Decisions about treating Paget's disease can be comp...

Drug Index

Pagoclone is an anxiolytic agent from the cyclopyrrolone family, related to better-known drugs such as the sleeping medication zopiclone. It was synthesized by a French team working for Rhone-Poulenc & Rorer S.A.[1] Pagoclone belongs to the class of nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures. It was never commercialised. It binds with roughly equivalent high affinity (0.7–9.1 nM) to t...

Menthol

.mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1} Menthol Names Preferred IUPAC name 5-Methyl-2-(propan-2-yl)cyclohexan-1-ol Other names 2-Isopropyl-5-methylcyclohexan-1-ol2-Isopropyl-5-methylcyclohexanol3-p-MenthanolHexahydrothymolMenthomentholPeppermint camphor Identifiers CAS Number 2216-51-5 (levomenthol)Y89-78-1 (racement...

Drug Category

An analgesic is any member of the group of drugs used to achieve analgesia, relief from pain. The word analgesic derives from Greek αν - ("without") and λγος - ("pain").[1] Commonly known as painkillers, analgesic drugs act in various ways on the peripheral and central nervous systems. They are distinct from anesthetics, which reversibly eliminate sensation, and include paracetamol (known in the US as acetaminophen or simply APAP), the non-steroidal anti-inflamma...

Drug Category

An analgesic is any member of the group of drugs used to achieve analgesia, relief from pain. The word analgesic derives from Greek αν - ("without") and λγος - ("pain").[1] Commonly known as painkillers, analgesic drugs act in various ways on the peripheral and central nervous systems. They are distinct from anesthetics, which reversibly eliminate sensation, and include paracetamol (known in the US as acetaminophen or simply APAP), the non-steroidal anti-inflamma...

Drug Category

An analgesic is any member of the group of drugs used to achieve analgesia, relief from pain. The word analgesic derives from Greek αν - ("without") and λγος - ("pain").[1] Commonly known as painkillers, analgesic drugs act in various ways on the peripheral and central nervous systems. They are distinct from anesthetics, which reversibly eliminate sensation, and include paracetamol (known in the US as acetaminophen or simply APAP), the non-steroidal anti-inflamma...

Drug Index

Palbociclib, sold under the brand name Ibrance among others, is a medication developed by Pfizer for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.[1][2] Palbociclib was the first CDK4/6 inhibitor to be approved as a cancer therapy.[3] Contents 1 Mechanism of action 2 Administration 3 Approvals and indications 3.1 HR+ breast cancer 4 Adverse effects 5 ...

Carbinoxamine

Carbinoxamine is an antihistamine and anticholinergic agent. It is used for hay fever, vasomotor rhinitis, mild urticaria, angioedema, dermatographism and allergic conjunctivitis. Carbinoxamine is a histamine antagonist, specifically an H1-antagonist. The maleic acid salt of the levorotatory isomer is sold as the prescription drug rotoxamine. It was patented in 1947 and came into medical use in 1953.[1] It was first launched in the United States by the McNeil Corporation under...

Carbinoxamine + Pseudoephedrine

Carbinoxamine/pseudoephedrine is an antihistamine and decongestant combination, marketed as Rondec, Ceron and Coldec. It contains two active ingredients: carbinoxamine and pseudoephedrine. References https://www.drugs.com/cdi/rondec.html .mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-...

Drug Index

Palifermin (trade name Kepivance, marketed by Biovitrum) is a truncated human recombinant keratinocyte growth factor (KGF)[1] produced in Escherichia coli. KGF stimulates the growth of cells that line the surface of the mouth and intestinal tract.[2] Contents 1 Therapeutic use(s) 2 Drug target and mechanism of action 3 Side effects 4 Administration 5 Drug interactions 6 Pre-clinical trials 6.1 Toxicology studies 7 Clinical trials 7.1 Phase I 7.2 Phase II ...

Drug Index

Paliperidone, sold under the trade name Invega among others, is an atypical antipsychotic. It is mainly used to treat schizophrenia and schizoaffective disorder. It is marketed by Janssen Pharmaceuticals. An extended release formulation is available that uses the OROS extended release system to allow for once-daily dosing. Paliperidone palmitate is a long-acting injectable formulation of paliperidone palmitoyl ester. It is on the World Health Organization's List of Essential Medicines.&#...