How Long Should I Use Prolia

I have taken Prolia in 2013, I received 2 shots, felt ache, tired, hips hurt, stopped it in 2015 because I had osteopenia, just went for a Bone Density and now I have very bad osteoporosis, I am still on the fence if I should take the Prolia shot again...How do I make my decision....I don't want to break any bones but so scared of all the side effects... ## This medication can cause some serious side effects, such as nausea, dizziness, administraton site irritation, worsening of asthma symptoms, as well as severe joint/muscle aches, according to FDA reports. Did your doctor offer you any other options? Are you on any other medications? Prolia is not the only medication, there are others you can try. Do you take any calcium and vitamin D supplements? ## You have a valid reason for no...

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How many inj's. of Prolia are safe to take? Over how many years? ## Hi Judy, From my personal investigation, there doesn't appear to be a set number of inj's or time frame for the duration of therapy associated with Prolia. I have a feeling it's solely based on your doctor's discretion... And if that is the case, perhaps your prescribing doctor can provide more specific details on that. Additionally, there's a popular discussion thread here comprised of patient comments & reviews from their experience with Prolia therapy that may help you with your research at: Prolia Side Effects. ClinicalTrials.gov provides some insight on Prolia as well. I hope this helps, as I too would be interested in knowing what the cut off point is, if any...

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Denosumab

Denosumab (trade names Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.[1][2] Denosumab is contraindicated in people with low blood calcium levels. The most common side effects are joint and muscle pain in the arms or legs.[3] Denosumab is a inhibitor of RANKL (receptor activator of nuclear factor kappa-Β ligand),[1&...

So, do I take the Prolia shot because I have osteoporosis, high risk for fracture, and higher risk because I just started Arimidex. I have been on Arimidex for one month, and no side effects so far. I don't like what I have been reading about Prolia and I don't want any more issues. I'm 59 still work full time, walk an hour twice a week, and weights on the other days, do the best I can on eating right. I don't want to feel bad and can't work, but I also don't want to end up in a wheel chair,so my husband can take care of me. That's not quality of life! I have an appointment June 26 but going out of town on the 29th don't know what to do? ## Hi, Irene! There have been many complaints about problems with the Prolia shot. What I would suggest is going in and...

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I had my first injection on Feb.16th. I am 72 years young. I have neck and shoulder pain off and on. Aqua Relaxing class at the Y has helped this but since the shot I am having more pain in neck and across my shoulders on both sides. Not sure if injection could cause this. I have a lot of stress in my life and also slept in a twin bed for a few days after shot and thought pain started with that. Not sure if that was the cause? Should I call the Dr.,or Chiropractor or get a massage?It seems to come and go but it has me worried. ## You should contact your doctor. There have been quite a few reports of Prolia causing pain in some people and it has often resulted in their no longer being able to use it. Only your doctor is going to be able to help you discover if it is from the Prolia and h...

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After the forth shot of Prolia I am experiencing leg pain. I will stop taking the injection but are the side effects able to reverse? ## Hello, Estelle! How are you feeling? I am very sorry about the problem that you've run into. You are not the first to complain about Prolia and I am expecting many more still to follow, it just doesn't seem to work well for many people. And yes, though it will take time, most side effects do eventually wear off. Is there anything else I can help with? ## Ive had 2 shots so far 60 mlgs in 12 months. My dexa scan was very bad all over me . since shots my bonescache 5x worse and head aches cant sleep anxiety. An more. I have other medical problems. Scared not sure if i should stop are go on and do the other 4 shots he ask me to take..... Idk ## Si...

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My bone density loss was -2.6 on December 2015, but after my third shot, my bone scan came back as -2.0 and I am going for a 4th shot this month. Can you tell me how many more shots I can go for, in order to become normal? I know my doctor might not be able to tell me how long. Please give me advice. Thank you! ## It sounds like your bone density loss has improved since the third shot. Do you find that to be the case as well based on how you feel? Have you gotten your 4th shot yet? And have any bone density results came back after the 4th shot to help determine your progress? In regards to how many shots one may need in order for bone density to become normal, my conclusion based on other Prolia discussion threads here, is that there's no way to know for certain because we all respo...

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I take ldn for ms...it does help my energy level. My dr wants me to start Prolia for osteoporosis. This drug effects the immune system. I know ldn helps to boost the immune system. Can these 2 drugs be taken together? I need to make a decision soon. I'd like to hear about anyone with ms using Prolia.....I'm scared. ## I just had a Prolia injection 2 weeks ago. I can tell you this, I would rather be in a wheelchair in a nursing home than have this in my system. It completely and totally DELETES YOUR IMMUNE SYSTEM. I'm really sick and need to go to the ER but I cannot be around other sick people without an immune system. I will NEVER have another one in my lifetime. Also have a couple of very needed surgeries scheduled that will most probably be cancelled because I have NO IMM...

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I have had 3 Prolia injections. I was diagnosed with Osteoporosis when I had a severe fracture of my ankle. I knew I had Osteopenia but had to stop Fosamax due to severe foot cramping. The first cycle of Prolia I was fine. The second cycle I experienced horrible relux problems about 1 month out from injection - this continued for several months. Then I broke out in a rash on my back - very itchy - scratched til it bled. Dermatologist swears it cannot be from the Prolia. Well the rash calmed down on my back and I went ahead with the third injection in April. Within weeks my back started itching and now its in my scalp itchy plaque like lesions - GROSS! I will not get another of these injections. I don't think anyone knows what this drug does. I have not had a followup Dexa scan yet. ...

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I had a shot about 4-5 months ago(due for another one), doubt I'll put that into my system again ! I now am havin bi-lateral hip pain that awakes me every night, and when I walk, I'm stiff !!! Never had these things before, so it seems to me, that the longer it's in your body, the worse off you are ! JMHO. Sent a letter to MD that gace it to me w/black box warning and it said "druge not to take". I have not heard fromher on that note. She probably has nothing else to offer me. She stopped RECLAST after 4 doses,b/c she was getting lomg bone crumbling fractures in some of her patients. So we shall see what the next round of "poison" people will think of for us !!! Good Luck to you all ## Hello, Antonette! Sorry about the pain that you're experiencing. You a...

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Took my first Prolia shot 4 days ago. I am having severe jaw pain. Most people can hear my jaw moving and it feels and sounds like it is cracking. I am going to report to FDA and of course make an appointment with my dentist. I just finished treatment for breast cancer and have to take an aromatase inhibitor for 5 years which causes weakining of bones which is why they prescribed Prolia. I am just beginning but I will never take another dose of Prolia. ## HI! Very sorry that you're in pain and miserable. There have actually been many complaints about Prolia causing these types of issues and many people are refusing to continue on it. Hopefully, it's just some inflammation or something from it and not a more serious problem. Can you post back after you see the dentist and let mw ...

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I have just had the Prolia injection. So far no side affects that I am aware of. Is there anyone who has continued with Prolia (Denosumab) and had positive results after three years? thanks ## There are many people that have experienced good results from Prolia. What you have to remember though, is that most of them have no reason to go hunting up a site like this to find more information on it. The people that usually post on sites like this one are those that have had a problem and are looking for help, or support. Typical side effects of this medication, according to the FDA, may include administration site reactions, muscle/bone pain, cough, swollen joints, and loose teeth. Can anyone that's done well on Prolia chime in with their experience? ## I just completed 2 shots (one ful...

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I had my first inyection by the end of June. I am 57 and had an spine fracture. Befo re prolia I was taken biophosphonates. So far so good, no side effects. Worried about the comments read. ## Hope everything is going well for you and that you will get improvements in your bones strenth. For me, unfortunately, taking a single injection of PROLIA on May 24, 2013 has resulted in ongoing suffering, as I have described in my earlier comments on this website. Would be Interested to know if you are still feeling no side effects 2-3 weeks after injection? ## Just had my first shot Monday feeling kinda like I've been poisoned. Hope this gets better , on my 4th day. Please tell me it gets better. I won't take it again.

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Have had osteopenia for few yrs., recently diagnosed with osteoporosis in lower spine. First prolia inj. Nov. 2013 and felt good for a few months. Then UTI which I rarely ever had before - bladder feels tender all the time. I am now 76. Use treadmill 20 min when able and yoga stretches. Plan to increase exercises regardless and just rest often. After 2nd inj. I had severe reflux for several weeks, then abdomenal pain and bloating, bowel issues. Now Ive had a headache, jaw and face pain for several days. Stiff neck. Nothing has helped it. I suffer from hypothroidism,osteoarthritis and fibromyalgia, so widespread pain is no stranger to me, but this is different. Keep pain Medications to a minimum. Wake up stiff for longer than usual. Currently taking ice packs to bed for burning hands and...

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I am under 100 lbs and have had 2 prolia shots and now experience hip pain. Should I have had a smaller dose due to my low weight? ## Hello, Jane! How are you? Yes, the dosage isn't adjusted due to weight or age. As to the hip pain, that can actually be a normal side effect of this medication, as listed by the FDA. You may also experience administration site irritation, redness, headache and nausea. Is there anything else I can help with?

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AMGEN has now admitted to us that PROLIA can cause SEIZURES. My 84 year old mother had a prolia shot in April 11th, and by May 8th she was in hospital with urinary infections and seizures. Doctors couldn't figure out what caused it. Again in September she was again admitted with urinary infections and seizure like symptoms. Mother has been in hospital for months due to this and now needs 24 hour care. I believe AMGEN should pay for this and am looking for a lawyer to take it on. I will post more when we get more results and proof, but BEWARE OF PROLIA.... IF YOU HAVE TAKEN IT, MAKE SURE IT IS ON YOUR DRUG LIST FOR PARAMEDICS AND DOCTORS AT THE HOSPITAL... as it is administered only twice a year, it is easily left off the list. ## I am very sorry about what happened to your mother. I...

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My Mum was given a 60mg injection of Prolia on 2nd May 2014. Ever since she has had severe abdominal pain, can't keep off the toilet and her lips have blistered and bled! This is awful and she wishes she had not had it. At 79 years old she suffers with osteoporosis and quite honestly was better off before the injection. I sincerely hope these side effects don't last for six months because she sure as hell won't be having a second dose. Be warned people, it seems that there are so many problems with this drug. ## Hello, Janet! How is your mother feeling? Yes, there have been many complaints about Prolia, there have even been people who managed to take it without a problem the first few times, then suddenly had a reaction.

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I've just recently had my second Prolia shot. So far so good...a little back pain. I continually have stress fractures on my feet and have also taken fosamax. My current problem is hair loss & I wondered if anyone else was having that problem? ## Hello, Gracie! How are you? No, this isn't listed from what I can find, but I'll check a couple more sources to be sure and post back. Are you on any other medications? How old are you? ## I'm 57. On no other meds except evista and a pill for reflux. A friend sent me a website that stated that there was a study with some hair loss ## Yes, after my second shot of Prolea, I had two UTIs, fatigue, huge bumps under the skin on my face and all over my scalp, an array of unexplained symptoms like peripheral neuropathy (not diabeti...

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On 11/6/12 I received a 60 mg dose of Prolia intravenously . Shortly afterwards ( a couple of days) I had severe diarrhea and flu like symptoms which cleared up in a week or so. THEN the jaw pain took over my life----- It was excruciating. I went for a scan of my jaw and was told that I have osteonecrosis of the jaw. Today, 11/1/13 some of the pain has eased but it is still difficult for me to eat chewy foods and to get a good night's sleep. To cough, sneeze or yawn causes severe pain. I get sharp pain in my ear mostly at night. My family doctor prescribed Alleve twice a day and a narcotic pain killer in between when the pain gets unbearable. I contacted the company (Amgen) and was told they were sorry for my problems but had nothing to reverse the symptoms. It has been nearly a yea...

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Hello, First I want to say I am 56 and almost never have medicaton problems. I had 4 rounds of chemo in 2010 and am doing great. My oncoligist said it would be benifical for me to have Prolia every 6 months. My T score waas good but he thought it would help me later. I had my first (and only) Prolia injection on 12/01/11. Six days later I was in severe pain and went to see my primary care physician and he sent me streight to the emergancy room.I had upper left abdominal pain and fever. I haven't been to the emergancy room in 25 years. Well I had all the usual tests and they thought it might be diverticulitis. New to me I never had that before. My primary doc and my ortho docs told me he didn't think it was diverticulitis and I should not have Prolia again. I am now having some j...

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