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Rifamycin

The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis rifamycinica or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex (MAC) infections. The rifamycin group includes the "classic" rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, r...

Desloratadine

Desloratadine (trade names Clarinex and Aerius) is a tricyclic H1 antagonist that is used to treat allergies. It is an active metabolite of loratadine. It was patented in 1984 and came into medical use in 2001.[3] Contents 1 Medical uses 2 Side effects 3 Interactions 4 Pharmacology 4.1 Pharmacodynamics 4.2 Pharmacokinetics 4.3 Pharmacogenomics 5 Society and culture 5.1 Economics 6 See also 7 References 8 External links Medical uses Desloratadine is used to treat ...

Chloroxylenol + Hydrocortisone + Pramoxine

Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953[1] and used as an antipruritic. During research and development, pramocaine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.[1] Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and ...

Flunisolide

Flunisolide (marketed as AeroBid among others) is a corticosteroid often prescribed as treatment for allergic rhinitis.[1] Intranasal corticosteroids are the most effective medication for controlling symptoms. [2] The principal mechanism of action of flunisolide is to activate glucocorticoid receptors, meaning it has an anti-inflammatory action. The effects of topical corticosteroids is not immediate and requires regular use and at least a few days to start exp...

Flunisolide

Flunisolide (marketed as AeroBid among others) is a corticosteroid often prescribed as treatment for allergic rhinitis.[1] Intranasal corticosteroids are the most effective medication for controlling symptoms. [2] The principal mechanism of action of flunisolide is to activate glucocorticoid receptors, meaning it has an anti-inflammatory action. The effects of topical corticosteroids is not immediate and requires regular use and at least a few days to start exp...

Povidone-Iodine

Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery.[1][2] It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for.[2] It may also be used for minor wounds.[2] It may be applied to the skin as a liquid or a powder.[2] Side effects include skin irritation and sometimes swelling.[1&...

Chlorpheniramine + Methscopolamine

Chlorphenamine (CP, CPM), also known as chlorpheniramine, is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis (hay fever).[2] It is taken by mouth.[2] The medication takes effect within 2 hours and lasts for about 4-6.[2] Common side effects include sleepiness, restlessness, and weakness.[2] Other side effects may include dry mouth and wheeziness.[2] It is a first-genera...

Flunisolide

Flunisolide (marketed as AeroBid among others) is a corticosteroid often prescribed as treatment for allergic rhinitis.[1] Intranasal corticosteroids are the most effective medication for controlling symptoms. [2] The principal mechanism of action of flunisolide is to activate glucocorticoid receptors, meaning it has an anti-inflammatory action. The effects of topical corticosteroids is not immediate and requires regular use and at least a few days to start exp...

Amphotericin B Lipid Formulations

Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis.[2] The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis.[3] For certain infections it is given with flucytosine.[4] It is typically given by injection into a vein.[3] Common side effects include a reaction with fever, chills, and headaches soo...

Drug Index

Abemaciclib (trade names Verzenio, Verzenios and Ramiven) is a drug for the treatment of advanced or metastatic breast cancers. It was developed by Eli Lilly and it acts as a CDK inhibitor selective for CDK4 and CDK6.[1] It was designated as a breakthrough therapy for breast cancer by the U.S. Food and Drug Administration (FDA) in October 2015.[2] On 28 September 2017, it was approved for use in the United States by the FDA for the treatment of certain breast ...

Drug Index

Abetimus (trade name Riquent) is an immunosuppressant.[1] It is a synthetic biological called a tolerogen. It is made of four double-stranded oligodeoxyribonucleotides that are attached to a carrier platform and are designed to block specific B-cell anti double stranded DNA antibodies.[2] It may also complex anti dsDNA antibodies together, therefore disabling them. This way abetimus was supposed to help treat systemic lupus erythematosus and specifically lupu...

Drug Index

Acebutolol,[1] sold under the brand names Sectral among others, is a beta blocker for the treatment of hypertension and arrhythmias. Acebutolol is a cardioselective beta-1 blocker and has intrinsic sympathetic activity. It is commonly used in the treatment of angina. It was patented in 1967 and approved for medical use in 1973.[2] Contents 1 Medical uses 2 Contraindications 3 Side effects 4 Pharmacology 5 Pharmacokinetics 6 References 7 External links M...

Drug Index

Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It was patented in 1983 and approved for medical use in 1992.[4] Contents 1 Side effects 2 Chemistry 3 Society and culture 3.1 Availability 4 References 5 External links Side effects Aceclofenac should not be given to people with porphyria or breast-feeding mothers, an...

Drug Index

Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It was patented in 1983 and approved for medical use in 1992.[4] Contents 1 Side effects 2 Chemistry 3 Society and culture 3.1 Availability 4 References 5 External links Side effects Aceclofenac should not be given to people with porphyria or breast-feeding mothers, an...

Drug Index

Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is generic, so is marketed under many brand names worldwide.[1] References .mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{colum...

Perindopril

Perindopril is a medication used to treat high blood pressure, heart failure, or stable coronary artery disease.[1] As a long-acting ACE inhibitor, it works by relaxing blood vessels and decreasing blood volume. As a prodrug, perindopril is hydrolyzed in the liver to its active metabolite, perindoprilat. It was patented in 1980 and approved for medical use in 1988.[2] Perindopril is taken in the form of perindopril arginine (trade names include Coversyl, Cove...

Drug Index

Medical foods are foods that are specially formulated and intended for the dietary management of a disease that has distinctive nutritional needs that cannot be met by normal diet alone. In the United States they were defined in the Food and Drug Administration's 1988 Orphan Drug Act Amendments[1] and are subject to the general food and safety labeling requirements of the Federal Food, Drug, and Cosmetic Act. In Europe the European Food Safety Authority established definitions...

Acetaminophen + Codeine

Codeine/paracetamol, also known as codeine/acetaminophen and co-codamol, is a compound analgesic consisting of a combination of codeine phosphate and paracetamol (acetaminophen). Co-codamol tablets are used for the relief of mild to moderate pain when paracetamol or NSAIDs such as ibuprofen, aspirin or naproxen alone do not sufficiently relieve a patient's symptoms, or where their use is ill-advised. In 2019, it was the 173rd most commonly prescribed medication in the United States, with more...

Acetylcysteine

Acetylcysteine, also known as N-acetylcysteine (NAC), is a medication that is used to treat paracetamol (acetaminophen) overdose, and to loosen thick mucus in individuals with chronic bronchopulmonary disorders like pneumonia and bronchitis.[2] It has been used to treat lactobezoar in infants. It can be taken intravenously, by mouth, or inhaled as a mist.[2] Some people use it as a dietary supplement.[6][7] Common side effects in...

Drug Index

Paracetamol, also known as acetaminophen,[a] is a medication used to treat fever and mild to moderate pain.[11][12] At a standard dose, paracetamol only slightly decreases body temperature;[11][13][14] it is inferior to ibuprofen in that respect,[15] and the benefits of its use for fever are unclear.[11][16][17] Paracetamol may reliev...