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Nanoparticle Albumin-Bound Paclitaxel

Protein-bound paclitaxel, also known as nanoparticle albumin–bound paclitaxel or nab-paclitaxel, is an injectable formulation of paclitaxel used to treat breast cancer, lung cancer and pancreatic cancer, among others. Paclitaxel kills cancer cells by preventing the normal breakdown of microtubules during cell division.[1][2][3] In this formulation, paclitaxel is bonded to albumin as a delivery vehicle.[4] It is manufacture...

Drug Index

Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) or aspirin, for the treatment of pain and headache. The various formulations combined with codeine are FDA-approved for the treatment of tension headaches. Butalbital has the same chemical formula as talbutal but a different structure—one that presents as 5-allyl-5-isobutylbarbituric acid.[2] Contents 1 Preparati...

Drug Index

Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) or aspirin, for the treatment of pain and headache. The various formulations combined with codeine are FDA-approved for the treatment of tension headaches. Butalbital has the same chemical formula as talbutal but a different structure—one that presents as 5-allyl-5-isobutylbarbituric acid.[2] Contents 1 Preparati...

Drug Index

Melatonin is a hormone primarily released by the pineal gland at night, and has long been associated with control of the sleep–wake cycle.[2][4] In vertebrates, melatonin is involved in synchronizing circadian rhythms, including sleep–wake timing and blood pressure regulation, and in control of seasonal rhythmicity including reproduction, fattening, moulting and hibernation.[5] Many of its effects are through activation of the melato...

Lactulose

Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy.[1][4] It is used by mouth for constipation and either by mouth or in the rectum for hepatic encephalopathy.[1] It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation.[2][3] Common side effects include abdominal bloating and cramps.[1] A potential exist...

Rabeprazole

Rabeprazole, sold under the brand name Aciphex, among others, is a medication that decreases stomach acid.[6] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and excess stomach acid production such as in Zollinger–Ellison syndrome.[6] It may also be used in combination with other medications to treat Helicobacter pylori.[7] Effectiveness is similar to other proton pump inhibitors (PPIs).[8] It is ...

Drug Index

Aciclovir (ACV), also known as acyclovir,[3] is an antiviral medication.[4] It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles.[5] Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein–Barr virus infection.[5][6] It can be taken by mouth, applied as a cream, or injected.[5] Common ...

Drug Category

Anthelmintics or antihelminthics are drugs that expel parasitic worms (helminths) from the body, by either stunning or killing them. They may also be called vermifuges (stunning) or vermicides (killing). Contents 1 Pharmaceuticals 2 Natural anthelmintics 3 Anthelmintic resistance 4 References 4.1 Footnotes 4.2 General references 5 External links Pharmaceuticals Benzimidazoles: Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms...

Drug Index

Alitretinoin, or 9-cis-retinoic acid, is a form of vitamin A. It is also used in medicine as an antineoplastic (anti-cancer) agent developed by Ligand Pharmaceuticals. It is a first generation retinoid. Ligand gained Food and Drug Administration (FDA) approval for alitretinoin in February 1999. Contents 1 Medical uses 1.1 Kaposi’s sarcoma 1.2 Chronic hand eczema 2 Adverse effects 2.1 Systemic use 2.2 Topical use 2.3 Contraindications 2.4 Interactions 2.5 Overdose 3 Mechanism of ...

Fexofenadine

Fexofenadine, sold under the brand name Allegra among others,[10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria.[11] Therapeutically, fexofenadine is a selective peripheral H1 blocker. It is classified as a second-generation antihistamine because it is less able to pass the blood–brain barrier and cause sedation, compared to first-generation antihistamines.[12][13...

Fexofenadine Hydrochloride

Fexofenadine, sold under the brand name Allegra among others,[10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria.[11] Therapeutically, fexofenadine is a selective peripheral H1 blocker. It is classified as a second-generation antihistamine because it is less able to pass the blood–brain barrier and cause sedation, compared to first-generation antihistamines.[12][13...

Fexofenadine Hydrochloride + Pseudoephedrine Hydrochloride

Fexofenadine, sold under the brand name Allegra among others,[10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria.[11] Therapeutically, fexofenadine is a selective peripheral H1 blocker. It is classified as a second-generation antihistamine because it is less able to pass the blood–brain barrier and cause sedation, compared to first-generation antihistamines.[12][13...

Fexofenadine + Pseudoephedrine

Fexofenadine, sold under the brand name Allegra among others,[10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria.[11] Therapeutically, fexofenadine is a selective peripheral H1 blocker. It is classified as a second-generation antihistamine because it is less able to pass the blood–brain barrier and cause sedation, compared to first-generation antihistamines.[12][13...

Acetaminophen + Butalbital

Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) or aspirin, for the treatment of pain and headache. The various formulations combined with codeine are FDA-approved for the treatment of tension headaches. Butalbital has the same chemical formula as talbutal but a different structure—one that presents as 5-allyl-5-isobutylbarbituric acid.[2] Contents 1 Preparati...

Drug Index

Alvimopan (trade name Entereg) is a drug which behaves as a peripherally acting μ-opioid receptor antagonist. With the limited ability to cross the blood–brain barrier and reach the μ-opioid receptors of the central nervous system, the clinically undesirable effects of centrally acting opioid antagonists (like reversal of opioid-mediated analgesia) are avoided without affecting the intended blockade of μ-opioid receptors in the gastrointestinal tract.[1]&a...

Drug Category

Anthelmintics or antihelminthics are drugs that expel parasitic worms (helminths) from the body, by either stunning or killing them. They may also be called vermifuges (stunning) or vermicides (killing). Contents 1 Pharmaceuticals 2 Natural anthelmintics 3 Anthelmintic resistance 4 References 4.1 Footnotes 4.2 General references 5 External links Pharmaceuticals Benzimidazoles: Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms...

Drug Index

Amifampridine is used as a drug, predominantly in the treatment of a number of rare muscle diseases. The free base form of the drug has been used to treat congenital myasthenic syndromes and Lambert–Eaton myasthenic syndrome (LEMS) through compassionate use programs since the 1990s and was recommended as a first line treatment for LEMS in 2006, using ad hoc forms of the drug, since there was no marketed form. Around 2000 doctors at Assistance Publique – Hôpitaux de Paris crea...

Drug Index

Azor is a city in Israel. Azor may also refer to: Azor, small town in the Tel Aviv District of Israel Azor (landowner), an 11th-century landowner Azor (horse) (foaled 1814), a British Thoroughbred racehorse The trade name of the following pharmaceutical drugs: Olmesartan/amlodipine (in the US) Alprazolam (in South Africa) Azor (film), an Argentine–French–Swiss drama See also Asor Azores Azur (disambiguation) Azure (disambiguation) Hazor (disambiguation) Topics referred to by th...

Drug Index

Lansoprazole, sold under the brand name Selanz SR among others, is a medication which reduces stomach acid.[2] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome.[3] Effectiveness is similar to other proton pump inhibitors (PPIs).[4] It is taken by mouth.[2] Onset is over a few hours and effects last up to a couple of days.[2] Common side effects include...

Dalfampridine

4-Aminopyridine (4-AP, fampridine, dalfampridine) is an organic compound with the chemical formula C5H4N–NH2. The molecule is one of the three isomeric amines of pyridine. It is used as a research tool in characterizing subtypes of the potassium channel. It has also been used as a drug, to manage some of the symptoms of multiple sclerosis,[6][7] and is indicated for symptomatic improvement of walking in adults with several variations of the disease.&am...